Doctor Timothy Tan

Doctor Timothy Tan

Conjoint Professor,
School of Medicine

Biography

Organisational Unit (School / Division)

  • School of Medicine

Contact

Email: T.Tan@westernsydney.edu.au
Phone:

Mobile:
Location:

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Publications

Journal Articles

  • Soares, J., Carvalho, V., Lodi-Junqueira, L., Fonseca, I., Athayde, G., de Sales, I., Caldas, A., Carvalho, P., Matos, T., Mello, L., Esteves, W., Tan, T., Levine, R., Hung, J. and Nunes, M. (2024), 'Assessment of the left atrial volume and function following percutaneous mitral balloon valvuloplasty : insights into acute and late impact of atrial fibrillation on atrial remodeling', International Journal of Cardiology, vol 394 .
  • Akhtar, Z., Trent, M., Moa, A., Tan, T., Frobert, O. and MacIntyre, C. (2023), 'The impact of COVID-19 and COVID vaccination on cardiovascular outcomes', European Heart Journal Supplements, vol 25, no Suppl. A , pp 42 - 49.
  • Chen, H., Bhat, A., Gan, G., Khanna, S., Ahlenstiel, G., Negishi, K. and Tan, T. (2023), 'The impact of body mass index on cardiac structure and function in a cohort of obese patients without traditional cardiovascular risk factors', International Journal of Cardiology: Cardiovascular Risk and Prevention, vol 19 .
  • Caldas, M., Esteves, W., Nascimento, B., Hung, J., Levine, R., Silva, V., Castro, M., Chavez, L., Silva, J., Mello, L., Ruffo, F., Andrade, A., Tan, T., Passaglia, L., Freire, C. and Nunes, M. (2023), 'Clinical outcomes and progression rate of tricuspid regurgitation in patients with rheumatic mitral valve disease', Open Heart, vol 10, no 2 .
  • Kpozehouen, E., Arrudsivah, B., Tan, T. and Macintyre, C. (2023), 'Knowledge, attitudes and practices of health care workers in a cardiology department on influenza vaccination', Vaccine, vol 41, no 14 , pp 2349 - 2356.
  • Pavasini, R., Sinning, C., Campo, G. and Tan, T. (2023), 'ObsErvatioNal prospective multicenter stuDy tO characterize the cLinical ANd DiagnoStiC feAtures of endocarditis in the contemPorary Era (ENDO-LANDSCAPE study) : rationale and design', Journal of Cardiovascular Medicine, vol 24, no 6 , pp 354 - 360.
  • Sales, I., Lodi-Junqueira, L., Athayde, G., Alcici, M., Diamantino, T., Silva, L., Macedo, F., Fraga, C., Spalaor, B., Valente, P., Soares, J., Tan, T., Esteves, W. and Nunes, M. (2022), 'Pulmonary artery pressure response to percutaneous mitral valvuloplasty : associated factors and clinical implications', Catheterization and Cardiovascular Interventions, vol 99, no 3 , pp 915 - 923.
  • Malaty, M., Amarasekera, A., Li, C., Scherrer-Crosbie, M. and Tan, T. (2022), 'Incidence of immune checkpoint inhibitor mediated cardiovascular toxicity : a systematic review and meta-analysis', European Journal of Clinical Investigation, vol 52, no 12 .
  • Gomes, N., Silva, V., Levine, R., Esteves, W., De Castro, M., Passos, L., Dal-Bianco, J., Pantaleao, A., Padilha da Silva, J., Tan, T., Dutra, W., Aikawa, E., Hung, J. and Nunes, M. (2022), 'Progression of mitral regurgitation in rheumatic valve disease : role of left atrial remodeling', Frontiers in Cardiovascular Medicine, vol 9 .
  • Conte, E., Revaiah, P. and Tan, T. (2022), 'Pericardial diseases : the emerging role for cardiac magnetic resonance imaging in the diagnosis of pericardial diseases', European Heart Journal - Case Reports, vol 6, no 4 .
  • Hassan, M., Awadalla, M., Tan, T., Scherrer-Crosbie, M., Bakar, R., Drobni, Z., Zarif, A., Gilman, H., Supraja, S., Nikolaidou, S., Zhang, L., Zlotoff, D., Hickey, S., Patel, S., Januzzi, J., Keane, F., Passeri, J., Neilan, T., MacDonald, S. and Jimenez, R. (2022), 'Serial measurement of global longitudinal strain among women with breast cancer treated with proton radiation therapy : a prospective trial for 70 patients', International Journal of Radiation Oncology Biology Physics, vol 115, no 2 , pp 398 - 406.
  • Moa, A., Tan, T., Wei, J., Hutchinson, D. and MacIntyre, C. (2022), 'Burden of influenza in adults with cardiac arrest admissions in Australia', International Journal of Cardiology, vol 361 , pp 109 - 115.
  • Kpozehouen, E., Tan, T. and Macintyre, C. (2022), 'Uptake of influenza, pneumococcal and herpes zoster vaccines among people with heart failure and atrial fibrillation', Vaccine, vol 40, no 52 , pp 7709 - 7713.
  • Pavasini, R., Tan, T. and Sinning, C. (2022), 'Timing for diagnosis and treatment in initially uncomplicated endocarditis : still a thorny issue', European Heart Journal - Case Reports, vol 6, no 2 .
  • Malaty, M., Kayes, T., Amarasekera, A., Kodsi, M., MacIntyre, C. and Tan, T. (2021), 'Incidence and treatment of arrhythmias secondary to coronavirus infection in humans : a systematic review', European Journal of Clinical Investigation, vol 51, no 2 .
  • Amarasekera, A., Chang, D., Schwarz, P. and Tan, T. (2021), 'Does vascular endothelial dysfunction play a role in physical frailty and sarcopenia? : a systematic review', Age and Ageing, vol 50, no 3 , pp 725 - 732.
  • Amarasekera, A., Chang, D., Schwarz, P. and Tan, T. (2021), 'Vascular endothelial dysfunction may be an early predictor of physical frailty and sarcopenia : a meta-analysis of available data from observational studies', Experimental Gerontology, vol 148 .
  • Amarasekera, A., Schwarz, P., Chang, D., Brakoulias, V. and Tan, T. (2021), 'Twin D-frail study protocol : does vitamin D link vascular endothelial dysfunction to sarcopenic frailty', Journal of Gerontology and Geriatric Medicine, vol 7, no 3 .
  • Bhat, A., Chen, H., Khanna, S., Gan, G., Abhayaratna, W., Nunes, M., MacIntyre, C. and Tan, T. (2021), 'Clinical and cardiac structural predictors of atrial fibrillation persistence', European Journal of Clinical Investigation, vol 51, no 3 .
  • Bartko, P., Heitzinger, G., Spinka, G., Pavo, N., Prausmuller, S., Kastl, S., Winter, M., Arfsten, H., Tan, T., Gebhard, C., Mascherbauer, J., Hengstenberg, C., Strunk, G., Hulsmann, M. and Goliasch, G. (2021), 'Principal morphomic and functional components of secondary mitral regurgitation', JACC: Cardiovascular Imaging, vol 14, no 12 , pp 2288 - 2300.
  • MacIntyre, C., Chughtai, A., Das, A., Rahman, B., Moa, A., Gan, C. and Tan, T. (2021), 'Effect of statin use on the risk of influenza and influenza vaccine effectiveness', International Journal of Cardiology, vol 332 , pp 205 - 208.
  • Bhat, A., Gan, G., Chen, H., Khanna, S., Nawaz, S., Nunes, M., Dobbins, T., MacIntyre, C. and Tan, T. (2021), 'Association of left atrial metrics with atrial fibrillation rehospitalization and adverse cardiovascular outcomes in patients with nonvalvular atrial fibrillation following index hospitalization', Journal of the American Society of Echocardiography, vol 34, no 10 , pp 1046 - 1055 3.
  • Bhat, A., Khanna, S., Chen, H., Gupta, A., Gan, G., Denniss, R., MacIntyre, R. and Tan, T. (2021), 'Integrated care in atrial fibrillation : a road map to the future', Circulation: Cardiovascular Quality and Outcomes, vol 14, no 3 , pp 347 - 362.
  • Bhat, A., Mahajan, V., Chen, H., Gan, G., Pontes-Neto, O. and Tan, T. (2021), 'Embolic stroke of undetermined source : approaches in risk stratification for cardioembolism', Stroke, vol 52, no 12 , pp 820 - 836.
  • Cristina de Castro Faria, S., Costa, H., Hung, J., Gorle de Miranda Chaves, A., Paes de Oliveira, F., Padilha da Silva, J., Esteves, W., Tan, T., Levine, R. and Nunes, M. (2020), 'Pulmonary artery systolic pressure response to exercise in patients with rheumatic mitral stenosis : determinants and prognostic value', Journal of the American Society of Echocardiography, vol 33, no 5 , pp 550 - 558.
  • Rao, K., Bhaskaran, A., Choudhary, P. and Tan, T. (2020), 'The role of multimodality imaging in the diagnosis of left ventricular noncompaction', European Journal of Clinical Investigation, vol 50, no 9 .
  • Khanna, S., Bhat, A., Chen, H., Tan, J., Gan, G. and Tan, T. (2020), 'Left Ventricular Sphericity Index is a reproducible bedside echocardiographic measure of geometric change between acute phase Takotsubo's syndrome and acute anterior myocardial infarction', IJC Heart and Vasculature, vol 29 .
  • Nunes, M., Levine, R., Braulio, R., Pascoal-Xavier, M., Elmariah, S., Gomes, N., Soares, J., Esteves, W., Zeng, X., Dal-Bianco, J., Passos, L., Passaglia, L., Ribeiro, V., Gelape, C., Costa, P., Lodi-Junqueira, L., Dutra, W., Tan, T., Aikawa, E. and Hung, J. (2020), 'Mitral regurgitation after percutaneous mitral valvuloplasty : insights into mechanisms and impact on clinical outcomes', JACC: Cardiovascular Imaging, vol 13, no 12 , pp 2513 - 2526.
  • Bhat, A., Khanna, S., Chen, H., Gan, G., MacIntyre, C. and Tan, T. (2020), 'Drivers of hospitalization in atrial fibrillation : a contemporary review', Heart Rhythm, vol 17, no 11 , pp 1991 - 1999.
  • Bhat, A., Khanna, S., Chen, H., Lee, L., Gan, G., Negishi, K., MacIntyre, C., Nunes, M. and Tan, T. (2020), 'Impairment of left atrial function and cryptogenic stroke : potential insights in the pathophysiology of stroke in the young', International Journal of Cardiology Heart and Vasculature, vol 26 .
  • Grapsa, J., Tan, T., Nunes, M., O'Regan, D., Durighel, G., Howard, L., Gibbs, J. and Nihoyannopoulos, P. (2020), 'Prognostic impact of right ventricular mass change in patients with idiopathic pulmonary arterial hypertension', International Journal of Cardiology, vol 304 , pp 172 - 174.
  • Chughtai, A., Tan, T., Hitchen, E., Kunasekaran, M. and MacIntyre, C. (2020), 'Association of influenza infection and vaccination with cardiac biomarkers and left ventricular ejection fraction in patients with acute myocardial infarction', International Journal of Cardiology Heart & Vasculature, vol 31 .
  • Tan, T., Nunes, M., Handschumacher, M., Pontes-Neto, O., Park, Y., O'Brien, C., Piro, V., Kim, G., Helenius, J., Zeng, X., Padilha da Silva, J., Furie, K., Ay, H. and Hung, J. (2020), 'Left atrial cross-sectional area is a novel measure of atrial shape associated with cardioembolic strokes', Heart, vol 106, no 15 , pp 1176 - 1182.
  • Bhat, A., Gan, G., Makarious, D., Tan, E., Chen, H., Wolfe, N., Lee, L., Burdusel, C., Nunes, M., Chow, C. and Tan, T. (2020), 'Characterisation of recent trends in cardiovascular risk factors in young and middle-aged patients with ischaemic stroke and/or transient ischaemic attack', Journal of the Neurological Sciences, vol 418 .
  • Santos Junior, O., Costa Rocha, M., Almeida, F., Cunha, P., Souza, S., Saad, G., Deus Queiroz Santos, T., Ferreira, A., Tan, T. and Nunes, M. (2019), 'Speckle tracking echocardiographic deformation indices in Chagas and idiopathic dilated cardiomyopathy : incremental prognostic value of longitudinal strain', PLoS One, vol 14, no 8 .
  • Raj, S., Chughtai, A., Sharma, A., Tan, T. and MacIntyre, C. (2019), 'Cost-benefit analysis of a national influenza vaccination program in preventing hospitalisation costs in Australian adults aged 50-64 years old', Vaccine, vol 37, no 40 , pp 5979 - 5985.
  • Bartko, P., Arfsten, H., Frey, M., Heitzinger, G., Pavo, N., Cho, A., Neuhold, S., Tan, T., Strunk, G., Hengstenberg, C., Hulsmann, M. and Goliasch, G. (2019), 'Natural history of functional tricuspid regurgitation : implications of quantitative doppler assessment', JACC: Cardiovascular Imaging, vol 12, no 3 , pp 389 - 397.
  • Athayde, G., Nascimento, B., Elmariah, S., Lodi-Junqueira, L., Soares, J., Saad, G., Padilha da Silva, J., Tan, T., Hung, J., Palacios, I., Levine, R. and Nunes, M. (2019), 'Impact of left atrial compliance improvement on functional status after percutaneous mitral valvuloplasty', Catheterization and Cardiovascular Interventions, vol 93, no 1 , pp 156 - 163.
  • De-Paula, C., Magalhaes, G., Jentzsch, N., Botelho, C., Mota, C., Murca, T., Ramalho, L., Tan, T., Capuruco, C. and Rodrigues-Machado, M. (2018), 'Echocardiographic assessment of ventricular function in young patients with asthma', Arquivos Brasileiros de Cardiologia, vol 110, no 3 , pp 231 - 239.
  • Mehrotra, P., Jansen, K., Tan, T., Flynn, A. and Hung, J. (2018), 'Clinical features and prognosis of patients with isolated severe aortic stenosis and valve area less than 1.0 cm2', Heart, vol 104, no 3 , pp 222 - 229.
  • Assuncao, B., Handschumacher, M., Brunner, A., Yucel, E., Bartko, P., Cheng, K., Campos, O., Fathi, A., Tan, T. and Scherrer-Crosbie, M. (2017), 'Acute leukemia is associated with cardiac alterations before chemotherapy', Journal of the American Society of Echocardiography, vol 30, no 11 , pp 1111 - 1118.
  • Nunes, M., Tan, T., Elmariah, S., Lodi-Junqueira, L., Nascimento, B., do Lago, R., da Silva, J., Reis, R., Zeng, X., Palacios, I., Hung, J. and Levine, R. (2017), 'Net atrioventricular compliance is an independent predictor of cardiovascular death in mitral stenosis', Heart, vol 103, no 23 , pp 1891 - 1898.
  • Esteves, W., Lodi-Junqueira, L., Soares, J., Athayde, G., Goebel, G., Carvalho, L., Zeng, X., Hung, J., Tan, T. and Nunes, M. (2017), 'Impact of percutaneous mitral valvuloplasty on left ventricular function in patients with mitral stenosis assessed by 3D echocardiography', International Journal of Cardiology, vol 248 , pp 280 - 285.
  • Fei, H., Ali, M., Tan, T., Cheng, K., Salama, L., Hua, L., Zeng, X., Halpern, E., Taghian, A., MacDonald, S. and Scherrer-Crosbie, M. (2016), 'Left ventricular global longitudinal strain in HER-2+ breast cancer patients treated with anthracyclines and trastuzumab who develop cardiotoxicity is associated with subsequent recovery of left ventricular ejection fraction', Echocardiography, vol 33, no 4 , pp 519 - 526.
  • Nunes, M., Nascimento, B., Lodi-Junqueira, L., Tan, T., Athayde, G. and Hung, J. (2016), 'Update on percutaneous mitral commissurotomy', Heart, vol 102, no 7 , pp 500 - 507.
  • Bhat, A., Gan, G., Tan, T., Hsu, C. and Denniss, R. (2016), 'Myocardial viability : from proof of concept to clinical practice', Cardiology Research and Practice, vol 2016 .
  • Tan, T., Zeng, X., Jiao, Y., Wang, L., Wei, Q., Thiele, K., Salgo, I., Mehta, V., Andrawes, M., Picard, M. and Hung, J. (2016), 'Three-dimensional field optimization method : clinical validation of a novel color doppler method for quantifying mitral regurgitation', Journal of the American Society of Echocardiography, vol 29, no 10 , pp 926 - 934.
  • Isaac, S., Tan, T. and Polly, P. (2016), 'Endoplasmic reticulum stress, calcium dysregulation and altered protein translation : intersection of processes that contribute to cancer cachexia induced skeletal muscle wasting', Current Drug Targets, vol 17, no 10 , pp 1140 - 1146.
  • Tan, T., Sawaya, H., Sebag, I., Cohen, V., Picard, M., Passeri, J., Kuter, I. and Scherrer-Crosbie, M. (2015), 'Time trends of left ventricular ejection fraction and myocardial deformation indices in a cohort of women with breast cancer treated with anthracyclines, taxanes, and trastuzumab', Journal of the American Society of Echocardiography, vol 28, no 5 , pp 509 - 514.

Previous Projects

Title: Does vitamin D deficiency cause frailty through its effects on early stage vascular dysfunction (endothelial dysfunction) - Interplay between vitamin D deficiency, chronic inflammation and sarcopenia
Funder:
  • Maridulu Budyari Gumal
Western Researchers: Anjalee Amarasekera and Timothy Tan
Years: 2019-09-02 - 2021-05-31
ID: P00026018

Western Sydney University

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Penrith NSW 2751

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