Doctor Lei Si

Doctor Lei Si

Associate Professor in Health Services Management,
Undergraduate Health Science

Biography

Dr Lei Si is an Associate Professor in Health Services Management at Western Sydney University. He is an Honorary Senior Fellow at the George Institute for Global Health and an Adjunct Professor at Nanjing Medical University. 

Dr Si undertakes research that employs health economics methods to promote efficient and equitable distribution of healthcare sources. He has extensive experience in cost-of-illness analysis, quality-of-life research, and health economic evaluation alongside clinical trials and model-based health economic evaluation. Dr Si has published over 100 papers in peer-reviewed journals. Many studies were published in top health economics or clinical research journals such as Circulation, JAMA Network Open, Value in Health, BMJ Global Health, Osteoporosis International, Quality of Life Research and Pharmacoeconomics. Lei's work has successfully attracted competitive funding of over $7 million from the NHMRC and MRFF (Australia), CIHR (Canada), NSFC (China), CMB (US), etc. 

Dr Si is Co-Editor-in-Chief of Health Economics Review and an Associate Editor for BMJ Global Health. He also serves on the editorial boards of several journals, including Osteoporosis International, Heliyon, International Journal of Rheumatic Diseases, Advances in Therapy, Frontiers in Public Health etc. He has been an External Evaluator of the Pharmaceutical Benefits Advisory Committee (PBAC). 

This information has been contributed by Doctor Si.

Qualifications

  • PhD University of Tasmania
  • MMgtSci Anhui Medical University
  • MSc Heidelberg University

Professional Memberships

  • Secretary and Board Member, China Health Policy and Management Society (2020 - 2024)

Awards

  • NHMRC Early Career Fellowship 2018-01-01
  • ESCEO-Eli Lilly 2018 Scholarship 2018-04-21
  • Australian and New Zealand Bone and Mineral Society Travel Grant 2017-06-19
  • ASMR Medical Research Week Tasmanian Postgraduate Student Research Award (Winner) 2015-05-22
  • ESCEO-Eli Lilly 2015 Scholarship 2015-03-23
  • Chinese Government Award for Outstanding Self-Financed Students Abroad 2015-02-13
  • International Osteoporosis Foundation (IOF) Young Investigator Award 2014-11-21
  • AHES Student Scholarship 2014-09-19
  • ISPOR Student Travel Grant 2014-09-29

Interests

  • Economic Evaluation
  • Health Economics
  • Health Services Management
  • Health Systems Research
  • Quality of Life
  • Systematic Review

Organisational Unit (School / Division)

  • Undergraduate Health Science

Committees

  • Editor-in-Chief, Health Economics Review
  • Associate Editor (Health Economics), BMJ Global Health
  • Faculty Advisor, ISPOR Sydney Student/ECR Chapter
  • Associate Editor, Frontiers in Public Health
  • Editorial Board, International Journal of Rheumatic Diseases
  • Editorial Board, Advances in Therapy
  • Secretary and Board Member, China Health Policy and Management Society

Contact

Email: L.Si@westernsydney.edu.au
Phone: (02) 4620 3655
Mobile:
Location: 24.2.06
Campbelltown

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Teaching

Current Teaching Areas

  • HLTH7024 Health Services Financing

Previous Teaching Areas

  • HLTH1012 Evidence in Health, 2023
  • HLTH7024 Health Services Financing, 2023
  • PUBH7030 Health Systems Planning and Evaluation, 2023

Publications

Journal Articles

  • Jiang, Y., Li, M., Jiang, S., Si, L. and Gu, Y. (2024), 'Patient welfare implications of indication-specific value-based pricing of multi-indication drugs', Value in Health, vol 27, no 3 , pp 273 - 277.
  • Xu, L., Chen, M., Angell, B., Jiang, Y., Howard, K., Jan, S. and Si, L. (2024), 'Establishing cost-effectiveness threshold in China : a community survey of willingness to pay for a healthylife year', BMJ Global Health, vol 9, no 1 .
  • Chimoriya, R., Mitlehner, K., Khoo, C., Osuagwu, U., Thomson, R., Si, L., Lean, M., Simmons, D. and Piya, M. (2024), 'Translation of a diabetes remission service into Australian primary care : findings from the evaluation of DiRECT-Australia', Journal of Diabetes Research, vol 2024 .
  • Lai, X., Yuan, i., Wang, H., Zhang, R., Qiao, Q., Feng, X., Jin, A., Li, H., Li, J., Si, L., Gao, P., Jan, S., Fang, H. and Wu, Y. (2024), 'Cost-effectiveness of salt substitute and salt supply restriction in eldercare facilities : the DECIDE-Salt cluster randomized clinical trial', JAMA Network Open, vol 7, no 2 .
  • Xu, L., Zhao, T., Perry, L., Frost, S., Di Tanna, G., Wang, S., Chen, M., Kolt, G., Jan, S. and Si, L. (2024), '[In Press] Return on investment of fracture liaison services : a systematic review and analysis', Osteoporosis International, .
  • Chen, M., Xu, L., Si, L., Wang, Z. and Jan, S. (2023), 'Examining the level and distribution of catastrophic health expenditure from 2013 to 2018 : a province-level study in China', Economic Modelling, vol 121 .
  • Jiang, Y., Jiang, S., Li, L., Shi, S., Li, M. and Si, L. (2023), 'Cost effectiveness of denosumab for secondary prevention of osteoporotic fractures among postmenopausal women in China : an individual-level simulation analysis', Applied Health Economics and Health Policy, vol 21, no 3 , pp 489 - 499.
  • Jiang, J., Jiang, S., Ahumada-Canale, A., Chen, Z., Si, L., Jiang, Y., Yang, L. and Gu, Y. (2023), 'Breast cancer screening should embrace precision medicine : evidence by reviewing economic evaluations in China', Advances in Therapy, vol 40, no 4 , pp 1393 - 1417.
  • Si, L., Chen, X., Ouyang, M., Wang, X., Chen, G., Cao, Y., Wu, G., Zhang, J., Zhang, J., Liu, Y., Zhang, S., Song, L., Delcourt, C., Arima, H., Wang, L., Lung, T., Chen, M., Anderson, C. and Jan, S. (2023), 'Cost-effectiveness of low-dose compared to standard-dose alteplase for acute ischemic stroke in China : a within-trial economic evaluation of the ENCHANTED Study', Cerebrovascular Diseases, vol 52, no 2 , pp 145 - 152.
  • Liu, Q., Davis, J., Han, X., Mackey, D., MacGregor, S., Craig, J., Si, L. and Hewitt, A. (2023), 'Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia', Eye, vol 37, no 11 , pp 2335 - 2343.
  • Xu, L., Chen, M., Peng, K., Hiligsmann, M., Jan, S. and Si, L. (2023), 'Socio-demographic disparities in health-related quality of life after hip fracture in China : evidence from the China Health and Retirement Longitudinal Study', Archives of Osteoporosis, vol 18, no 1 .
  • Moles, R., Perry, L., Naylor, J., Center, J., Ebeling, P., Duque, G., Major, G., White, C., Yates, C., Jennings, M., Kotowicz, M., Tran, T., Bliuc, D., Si, L., Gibson, K., Basger, B., Bolton, P., Barnett, S., Hassett, G., Kelly, A., Bazarnik, B., Ezz, W., Luckie, K. and Carter, S. (2023), 'Safer medicines to reduce falls and refractures for OsteoPorosis (#STOP) : a study protocol for a randomised controlled trial of medical specialistinitiated pharmacist-led medication management reviews in primary care', BMJ Open, vol 13, no 8 .
  • Deng, P., Fu, Y., Chen, M., Wang, D. and Si, L. (2023), 'Temporal trends in inequalities of the burden of cardiovascular disease across 186 countries and territories', International Journal for Equity in Health, vol 22, no 1 .
  • Deng, P., Chen, M. and Si, L. (2023), 'Temporal trends in inequalities of the burden of HIV/AIDS across 186 countries and territories', BMC Public Health, vol 23, no 1 .
  • Nguyen, A., Si, L., Lubel, J., Shackel, N., Yee, K., Wilson, M., Bradshaw, J., Hardy, K., Palmer, A., Blizzard, L. and de Graaff, B. (2023), 'Hepatocellular carcinoma surveillance based on the Australian consensus guidelines : a health economic modelling study', BMC Health Services Research, vol 23, no 1 .
  • Gong, E., Yang, B., Chen, X., Li, Y., Li, Z., Bettger, J., Oldenburg, B., Dong, D., Si, L. and Yan, L. (2023), 'An economic evaluation of a primary care-based technology-enabled intervention for stroke secondary prevention and management in rural China : a study protocol', Frontiers in Neurology, vol 14 .
  • Chen, C., Lin, Y., Liu, F., Chen, X., Billot, L., Li, Q., Guo, Y., Liu, H., Si, L., Ouyang, M., Zhang, C., Arima, H., Bath, P., Ford, G., Robinson, T., Sandset, E., Saver, J., Sprigg, N., van, d., Liu, G., Song, L., Yang, J., Li, G. and Anderson, C. (2023), 'Update on the INTEnsive ambulance-delivered blood pressure reduction in hyper-ACute stroke Trial (INTERACT4) : progress and baseline features in 2053 participants', Trials, vol 24, no 1 .
  • Wang, T., Si, L. and Jiang, Q. (2023), 'Induced abortions among Chinese adolescent girls', BMC Women's Health, vol 23, no 1 .
  • Liu, S., Liu, J., Si, L., Ke, X., Liu, L., Ren, Y., Bao, S., Li, F., Yu, Y., Pan, Q., Wei, Y. and Chen], Y. (2023), 'Patient preferences for anti-hyperglycaemic medication for type 2 diabetes mellitus in China : findings from a national survey', BMJ Global Health, vol 8, no 4 .
  • Deng, P., Liu, C., Chen, M. and Si, L. (2023), 'Knowledge domain and emerging trends in multimorbidity and frailty research from 2003 to 2023 : a scientometric study using citespace and VOSviewer', Health Economics Review, vol 13, no 1 .
  • Li, N., Si, L., Boonen, A., van den Bergh, J. and Hiligsmann, M. (2022), 'A model-based cost-effectiveness analysis of fracture liaison services in China', Archives of Osteoporosis, vol 17, no 1 .
  • Xia, Q., Campbell, J., Ahmad, H., de Graaff, B., Si, L., Otahal, P., Ratcliffe, K., Turtle, J., Marrone, J., Huque, M., Hagan, B., Green, M. and Palmer, A. (2022), 'Resource utilization and disaggregated cost analysis of bariatric surgery in the Australian public healthcare system', European Journal of Health Economics, vol 23, no 6 , pp 941 - 952.
  • Si, L., Robinson, A., Haines, T., Tierney, P. and Palmer, A. (2022), 'Cost analysis of employing general practitioners within residential aged care facilities based on a prospective, stepped-wedge, cluster randomised trial', BMC Health Services Research, vol 22, no 1 .
  • Fu, Y., Chen, M. and Si, L. (2022), 'Multimorbidity and catastrophic health expenditure among patients with diabetes in China : a nationwide population-based study', BMJ Global Health, vol 7, no 2 .
  • Zhou, G., Jan, S., Chen, M., Wang, Z. and Si, L. (2022), 'Equity in healthcare financing following the introduction of the unified residents' health insurance scheme in China', Health Policy and Planning, vol 37, no 2 , pp 209 - 217.
  • Zhang, H., Fu, Y., Chen, M. and Si, L. (2022), 'Socioeconomic inequality in health care use among cancer patients in China : evidence from the China Health and Retirement Longitudinal Study', Frontiers in Public Health, vol 10 .
  • Cai, D., Shi, S., Jiang, S., Si, L., Wu, J. and Jiang, Y. (2022), 'Estimation of the cost-effective threshold of a quality-adjusted life year in China based on the value of statistical life', European Journal of Health Economics, vol 23, no 4 , pp 607 - 615.
  • Jiang, S., Wang, Y., Si, L., Zang, X., Gu, Y., Jiang, Y., Liu, G. and Wu, J. (2022), 'Incorporating productivity loss in health economic evaluations : a review of guidelines and practices worldwide for research agenda in China', BMJ Global Health, vol 7, no 8 .
  • Li, K., Huang, L., Tian, M., Di Tanna, G., Yu, J., Zhang, X., Yin, X., Liu, Y., Hao, Z., Zhou, B., Feng, X., Li, Z., Zhang, J., Sun, J., Zhang, Y., Zhao, Y., Zhang, R., Yu, Y., Li, N., Yan, L., Labarthe, D., Elliott, P., Wu, Y., Neal, B., Lung, T. and Si, L. (2022), 'Cost-effectiveness of a household salt substitution intervention : findings from 20995 participants of the Salt Substitute and Stroke Study', Circulation, vol 145, no 20 , pp 1534 - 1541.
  • Xia, Q., Campbell, J., Si, L., Ahmad, H., de Graaff, B., Ratcliffe, K., Turtle, J., Marrone, J., Kuzminov, A. and Palmer, A. (2022), 'Healthcare resource utilisation and predictors for critical care unit admissions after primary bariatric surgery in an Australian public hospital setting : an exploratory study using a mixed-methods approach', Australian Health Review, vol 46, no 1 , pp 42 - 51.
  • Tew, M., Willis, M., Asseburg, C., Bennett, H., Brennan, A., Feenstra, T., Gahn, J., Gray, A., Heathcote, L., Herman, W., Isaman, D., Kuo, S., Lamotte, M., Leal, J., McEwan, P., Nilsson, A., Palmer, A., Patel, R., Pollard, D., Ramos, M., Sailer, F., Schramm, W., Shao, H., Shi, L., Si, L., Smolen, H., Thomas, C., Tran-Duy, A., Yang, C., Ye, W., Yu, X., Zhang, P. and Clarke, P. (2022), 'Exploring structural uncertainty and impact of health state utility values on lifetime outcomes in diabetes economic simulation models : findings from the ninth Mount Hood Diabetes Quality-of-Life challenge', Medical Decision Making, vol 42, no 5 , pp 599 - 611.
  • Si, L., Tu, L., Xie, Y., Chen, G., Hiligsmann, M., Yang, M., Zhang, Y., Zhang, X., Jiang, Y., Wei, Q., Gu, J. and Palmer, A. (2022), 'Evaluating health related quality of life in older people at risk of osteoporotic fracture : a head-to-head comparison of the EQ-5D-5L and AQoL-6D', Social Indicators Research, vol 160, no 2-3 , pp 809 - 824.
  • Xu, J., Yang, F., Si, L. and Qian, D. (2022), 'Do integrated health care interventions improve well-being among older adults with hypertension? : evidence from rural China', Social Indicators Research, vol 160, no 2-3 , pp 825 - 843.
  • Yang, F., Chen, M. and Si, L. (2022), 'What can we learn from China's health insurance reform to improve the horizontal equity of healthcare financing?', International Journal for Equity in Health, vol 21, no 1 .
  • Xia, Y., Lian, D., Yang, Y., Si, L., Ming, J., Wei, Y. and Chen, Y. (2022), 'The quality of published health economic evaluations on screening programs in China : a systematic review and quantitative appraisal', Expert Review of Pharmacoeconomics and Outcomes Research, vol 22, no 8 , pp 1277 - 1283.
  • Peng, K., Cai, W., Liu, X., Liu, Y., Shi, Y., Gong, J., Lei, L., Peng, J., Xie, Y., Zhao, H., Si, L. and Ouyang, M. (2022), 'Trends of hypercholesterolemia change in Shenzhen, China during 1997-2018', Frontiers in Public Health, vol 10 .
  • Deng, P., Fu, Y., Chen, M. and Si, L. (2022), 'Factors associated with health care utilization and catastrophic health expenditure among cancer patients in China : evidence from the China health and retirement longitudinal study', Frontiers in Public Health, vol 10 .
  • Palmer, A., Campbell, J., de Graaff, B., Devlin, N., Ahmad, H., Clarke, P., Chen, M. and Si, L. (2021), 'Population norms for quality adjusted life years for the United States of America, China, the United Kingdom and Australia', Health Economics, vol 30, no 8 , pp 1950 - 1977.
  • Peng, K., Zhou, L., Liu, X., Ouyang, M., Gong, J., Wang, Y., Shi, Y., Chen, J., Li, Y., Sun, M., Wang, Y., Lin, W., Yuan, S., Wu, B. and Si, L. (2021), 'Who is the main caregiver of the mother during the doing-the-month : is there an association with postpartum depression?', BMC Psychiatry, vol 21, no 1 .
  • Liu, S., Liu, J., Yu, Y., Si, L., Tang, C., Liu, Z. and Chen, Y. (2021), 'What is valued most by patients with type 2 diabetes mellitus when selecting second-line antihyperglycemic medications in China', Frontiers in Pharmacology, vol 12 .
  • Song, L., Chen, C., Chen, X., Guo, Y., Liu, F., Lin, Y., Billot, L., Li, Q., Liu, H., Si, L., Ouyang, M., Arima, H., Bath, P., Ford, G., Robinson, T., Sandset., E., Saver, J., Sprigg, N., van der Worp, H., Zhang, C., Yang, J., Li, G. and Anderson, C. (2021), 'INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4) : study protocol for a randomized controlled trial', Trials, vol 22, no 1 .
  • Ding, W., Ma, Y., Ma, C., Malone, D., Ma, A., Tang, W. and Si, L. (2021), 'The lifetime cost estimation of human papillomavirus-related diseases in China : a modeling study', Journal of Translational Internal Medicine, vol 9, no 3 , pp 200 - 211.
  • Xu, L., Jan, S., Chen, M. and Si, L. (2021), 'Sociodemographic and health system factors associated with variations in hospitalization costs for fractures in adults aged 45 years and over : a cross-sectional study of provincial health accounts in Jiangsu Province, China', Archives of Osteoporosis, vol 16, no 1 .
  • Si, L., Eisman, J., Winzenberg, T., Sanders, K., Center, J., Nguyen, T., Tran, T. and Palmer, A. (2021), 'Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis', Osteoporosis International, vol 32, no 10 , pp 2073 - 2081.
  • Boateng, G., Lartey, S., Baiden, P., Si, L., Biritwum, R., Kowal, P., Magnussen, C., Ben Taleb, Z., Palmer, A. and Luginaah, I. (2021), 'Measuring hypertension progression with transition probabilities : estimates from the WHO SAGE longitudinal study', Frontiers in Public Health, vol 9 .
  • Wang, Y., Duan, Z., Peng, K., Li, D., Ou, J., Wilson, A., Wang, N., Si, L. and Chen, R. (2021), 'Acute stress disorder among frontline health professionals during the COVID-19 outbreak : a structural equation modeling investigation', Psychosomatic Medicine, vol 83, no 4 , pp 373 - 379.
  • Jiang, Y., Cai, D., Chen, D., Jiang, S., Si, L. and Wu, J. (2021), 'Economic evaluation of remdesivir for the treatment of severe COVID-19 patients in China under different scenarios', British Journal of Clinical Pharmacology, vol 87, no 11 , pp 4386 - 4396.
  • Xu, L., Chen, M. and Si, L. (2021), 'Research progress, challenges, and recommendations of health economic evaluation in osteoporosis drugs', Chinese Journal of Endocrinology and Metabolism, vol 37, no 9 , pp 859 - 862.
  • Li, K., Tian, M., Neal, B., Huang, L., Yu, J., Liu, Y., Yin, X., Zhang, X., Wu, Y., Li, N., Elliott, P., Yan, L., Labarthe, D., Hao, Z., Shi, J., Feng, X., Zhang, J., Zhang, Y., Zhang, R., Zhou, B., Li, Z., Sun, J., Zhao, Y., Yu, Y., Si, L. and Lung, T. (2021), 'Protocol for the economic evaluation of the China Salt Substitute and Stroke Study (SSaSS)', BMJ Open, vol 11, no 7 .
  • Li, N., Cornelissen, D., Silverman, S., Pinto, D., Si, L., Kremer, I., Bours, S., de Bot, R., Boonen, A., Evers, S., van den Burgh, J., Reginster, J. and Hiligsmann, M. (2021), 'An updated systematic review of cost-effectiveness analyses of drugs for osteoporosis', PharmacoEconomics, vol 39, no 2 , pp 181 - 209.
  • Lung, T., Si, L., Hooper, R. and Di Tanna, G. (2021), 'Health economic evaluation alongside stepped wedge trials : a methodological systematic review', PharmacoEconomics, vol 39, no 1 , pp 63 - 80.
  • Lartey, S., de Graaff, B., Magnussen, C., Boateng, G., Aikins, M., Minicuci, N., Kowal, P., Si, L. and Palmer, A. (2020), 'Health service utilization and direct healthcare costs associated with obesity in older adult population in Ghana', Health Policy and Planning, vol 35, no 2 , pp 199 - 209.
  • Lartey, S., Si, L., Otahal, P., de Graaff , B., Boateng, G., Biritwum, R., Minicuci, N., Kowal, P., Magnussen, C. and Palmer, A. (2020), 'Annual transition probabilities of overweight and obesity in older adults : evidence from World Health Organization Study on global AGEing and adult health', Social Science and Medicine, vol 247 .
  • Xia, Q., Campbell, J., Ahmad, H., Si, L., de Graaff , B. and Palmer, A. (2020), 'Bariatric surgery is a cost-saving treatment for obesity : a comprehensive meta-analysis and updated systematic review of health economic evaluations of bariatric surgery', Obesity Reviews, vol 21, no 1 .
  • Hu, W., Xu, W., Si, L., Wang, C., Jiang, Q., Wang, L. and Cutler, H. (2020), 'Cost-effectiveness of the Da Qing Diabetes Prevention program : a modelling study', PLoS One, vol 15, no 12 .
  • Lartey, S., Si, L., Lung, T., Magnussen, C., Boateng, G., Minicuci, N., Kowal, P., Hayes, A., de Graaff, B., Blizzard, L. and Palmer, A. (2020), 'Impact of overweight and obesity on life expectancy, quality-adjusted life years and lifetime costs in the adult population of Ghana', BMJ Global Health, vol 5, no 9 .
  • Chen, M., Zhou, G. and Si, L. (2020), 'Ten years of progress towards universal health coverage : has China achieved equitable healthcare financing?', BMJ Global Health, vol 5, no 11 .
  • Le, Q., Blizzard, L., Si, L., Giang, L. and Neil, A. (2020), 'The evolution of social health insurance in Vietnam and its role towards achieving universal health coverage', Health Policy OPEN, vol 1 .
  • Haines, T., Palmer, A., Tierney, P., Si, L. and Robinson, A. (2020), 'A new model of care and in-house general practitioners for residential aged care facilities : a stepped wedge, cluster randomised trial', Medical Journal of Australia, vol 212, no 9 , pp 409 - 415.
  • Xia, Q., Campbell, J., Ahmad, H., Si, L., de Graaff, B., Otahal, P. and Palmer, A. (2020), 'Health state utilities for economic evaluation of bariatric surgery : a comprehensive systematic review and meta-analysis', Obesity Reviews, vol 21, no 8 .
  • Peng, K., Yang, M., Tian, M., Chen, M., Zhang, J., Wu, X., Ivers, R. and Si, L. (2020), 'Cost-effectiveness of a multidisciplinary co-management program for the older hip fracture patients in Beijing', Osteoporosis International, vol 31, no 8 , pp 1545 - 1553.
  • Cornelissen, D., de Kunder, S., Si, L., Reginster, J., Evers, S., Boonen, A., Hiligsmann, M. and European Society for Clinical and Economic Aspect , .. (2020), 'Interventions to improve adherence to anti-osteoporosis medications : an updated systematic review', Osteoporosis International, vol 31, no 9 , pp 1645 - 1669.
  • Si, L., Willis, M., Asseburg, C., Nilsson, A., Tew, M., Clarke, P., Lamotte, M., Ramos, M., Shao, H., Shi, L., Zhang, P., McEwan, P., Ye, W., Herman, W., Kuo, S., Isaman, D., Schramm, W., Sailer, F., Brennan, A., Pollard, D., Smolen, H., Leal, J., Gray, A., Patel, R., Feenstra, T. and Palmer, A. (2020), 'Evaluating the ability of economic models of diabetes to simulate new cardiovascular outcomes trials : a report on the Ninth Mount Hood Diabetes Challenge', Value in Health, vol 23, no 9 , pp 1163 - 1170.
  • Lartey, S., Magnussen, C., Si, L., Boateng, G., de Graaff, G., Biritwum, R., Minicuci, N., Kowal, P., Blizzard, L. and Palmer, A. (2019), 'Rapidly increasing prevalence of overweight and obesity in older Ghanaian adults from 2007-2015 : evidence from WHO-SAGE waves 1 & 2', PLoS One, vol 14, no 8 .
  • Si, L., Tu, L., Xie, Y., Palmer, A., Gu, Y., Zheng, X., Li, J., Lv, Q., Qi, J., Lin, Z., Chen, M., Gu, J. and Hiligsmann, M. (2019), 'Chinese patients' preference for pharmaceutical treatments of osteoporosis : a discrete choice experiment', Archives of Osteoporosis, vol 14, no 1 .
  • Lartey, S., Si, L., de Graaff, B., Magnussen, C., Ahmad, H., Campbell, J., Biritwum, R., Minicuci, N., Kowal, P. and Palmer, A. (2019), 'Evaluation of the association between health state utilities and obesity in sub-Saharan Africa : evidence from World Health Organization study on Global AGEing and Adult Health Wave 2', Value in Health, vol 22, no 9 , pp 1042 - 1049.
  • Si, L., Eisman, J., Winzenberg, T., Sanders, K., Center, J., Nguyen, T. and Palmer, A. (2019), 'Microsimulation model for the health economic evaluation of osteoporosis interventions : study protocol', BMJ Open, vol 9, no 2 .
  • Lartey, S., Magnussen, C., Si, L., de Graaff, B., Biritwum, R., Mensah, G., Yawson, A., Minicuci, N., Kowal, P., Boateng, G. and Palmer, A. (2019), 'The role of intergenerational educational mobility and household wealth in adult obesity : evidence from wave 2 of the world health organization's study on global ageing and adult health', PLoS One, vol 14, no 1 .
  • Wang, Z., Zhou, X., Gao, Y., Chen, M., Palmer, A. and Si, L. (2019), 'Did expansion of health insurance coverage reduce horizontal inequity in healthcare finance? : a decomposition analysis for China', BMJ Open, vol 9, no 1 .
  • McCaughey, T., Budden, D., Sanfilippo, P., Gooden, G., Fan, L., Fenwick, E., Rees, G., Macgregor, C., Si, L., Chen, C., Liang, H., Pebay, A., Baldwin, T. and Hewitt, A. (2019), 'A need for better understanding is the major determinant for public perceptions of human gene editing', Human Gene Therapy, vol 30, no 1 , pp 36 - 43.
  • Hong, D., Si, L., Jiang, M., Shao, H., Ming, W., Zhao, Y., Li, Y. and Shi, L. (2019), 'Cost effectiveness of sodium-glucose cotransporter-2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and dipeptidyl peptidase-4 (DPP-4) inhibitors : a systematic review', PharmacoEconomics, vol 37, no 6 , pp 777 - 818.
  • Hiligsmann, M., Reginster, J., Tosteson, A., Bukata, S., Saag, K., Gold, D., Halbout, P., Jiwa, F., Lewiecki, E., Pinto, D., Adachi, J., Al-Daghri, N., Bruyere, O., Chandran, M., Cooper, C., Harvey, N., Einhorn, T., Kanis, J., Kendler, D., Messina, O., Rizzoli, R., Si, L. and Silverman, S. (2019), 'Recommendations for the conduct of economic evaluations in osteoporosis : outcomes of an experts' consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation', Osteoporosis International, vol 30, no 1 , pp 45 - 57.
  • Li, X., Chen, M., Wang, Z. and Si, L. (2018), 'Forgone care among middle aged and elderly with chronic diseases in China : evidence from the China Health and Retirement Longitudinal Study baseline survey', BMJ Open, vol 8, no 3 .
  • Wang, Z., Li, X., Chen, M. and Si, L. (2018), 'Social health insurance, healthcare utilization, and costs in middle-aged and elderly community-dwelling adults in China', International Journal for Equity in Health, vol 17, no 1 .
  • Wang, L., Si, L., Cocker, F., Palmer, A. and Sanderson, K. (2018), 'A systematic review of cost-of-illness studies of multimorbidity', Applied Health Economics and Health Policy, vol 16, no 1 , pp 15 - 29.
  • Palmer, A., Si, L., Tew, M., Hua, X., Willis, M., Asseburg, C., McEwan, P., Leal, J., Gray, A., Foos, V., Lamotte, M., Feenstra, T., O'Connor, P., Brandle, M., Smolen, H., Gahn, J., Valentine, W., Pollock, R., Breeze, P., Brennan, A., Pollard, D., Ye, W., Herman, W., Isaman, D., Kuo, S., Laiteerapong, N., Tran-Duy, A. and Clarke, P. (2018), 'Computer modeling of diabetes and its transparency : a report on the Eighth Mount Hood Challenge', Value in Health, vol 21, no 6 , pp 724 - 731.
  • Wang, L., Cocker, F., Kilpatrick, M., Otahal, P., Si, L., Palmer, A. and Sanderson, K. (2018), 'The associations of multimorbidity with health-related productivity loss in a large and diverse public sector setting : a cross-sectional survey', Journal of Occupational and Environmental Medicine, vol 60, no 6 , pp 528 - 535.
  • Siddiqui, N., Dwyer, M., Stankovich, J., Peterson, G., Greenfield, D., Si, L. and Kinsman, L. (2018), 'Hospital length of stay variation and comorbidity of mental illness : a retrospective study of five common chronic medical conditions', BMC Health Services Research, vol 18, no 1 .
  • Chen, M., Qian, D., Feng, Z. and Si, L. (2018), 'Is outpatient care benefit distribution of government healthcare subsidies equitable in rural ethnic minority areas of China? : results from cross-sectional studies in 2010 and 2013', BMJ Open, vol 8, no 2 .
  • Si, L., Chen, M. and Palmer, A. (2017), 'Has equity in government subsidy on healthcare improved in China? : evidence from the China's National Health Services Survey', International Journal for Equity in Health, vol 16, no 1 .
  • de Graaff, B., Si, L., Neil, A., Yee, K., Sanderson, K., Gurrin, L. and Palmer, A. (2017), 'Population screening for hereditary haemochromatosis in Australia : construction and validation of a state-transition cost-effectiveness model', PharmacoEconomics - Open, vol 1, no 1 , pp 37 - 51.
  • Chen, M., Palmer, A. and Si, L. (2017), 'Improving equity in health care financing in China during the progression towards Universal Health Coverage', BMC Health Services Research, vol 17, no 1 .
  • Si, L., Shi, L., Chen, M. and Palmer, A. (2017), 'Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China', Quality of Life Research, vol 26, no 11 , pp 3049 - 3058.
  • Hua, X., Lung, T., Palmer, A., Si, L., Herman, W. and Clarke, P. (2017), 'How consistent is the relationship between improved glucose control and modelled health outcomes for people with type 2 diabetes mellitus? : a systematic review', PharmacoEconomics, vol 35, no 3 , pp 319 - 329.
  • de Graaff, B., Neil, A., Si, L., Yee, K., Sanderson, K., Gurrin, L. and Palmer, A. (2017), 'Cost-effectiveness of different population screening strategies for hereditary haemochromatosis in Australia', Applied Health Economics and Health Policy, vol 15, no 4 , pp 521 - 534.
  • McCaughey, T., Sanfilippo, P., Gooden, G., Budden, D., Fan, L., Fenwick, E., Rees, G., MacGregor, C., Si, L., Chen, C., Liang, H., Baldwin, T. and Pebay, A. (2016), 'A global social media survey of attitudes to human genome editing', Cell Stem Cell, vol 18, no 5 , pp 569 - 572.
  • Si, L., Winzenberg, T., Chen, M., Jiang, Q., Neil, A. and Palmer, A. (2016), 'Screening for osteoporosis in Chinese post-menopausal women : a health economic modelling study', Osteoporosis International, vol 27, no 7 , pp 2259 - 2269.
  • Chen, M., Palmer, A. and Si, L. (2016), 'Assessing equity in benefit distribution of government health subsidy in 2012 across East China : benefit incidence analysis', International Journal for Equity in Health, vol 15, no 1 .
  • Wang, L., Wang, A., FitzGerald, G., Si, L., Jiang, Q. and Ye, D. (2016), 'Who benefited from the New Rural Cooperative Medical System in China? : a case study on Anhui Province', BMC Health Services Research, vol 16, no 1 .
  • Nolan, M., Plana, J., Thavendiranathan, P., Shaw, L., Si, L. and Marwick, T. (2016), 'Cost-effectiveness of strain-targeted cardioprotection for prevention of chemotherapy-induced cardiotoxicity', International Journal of Cardiology, vol 212 , pp 336 - 345.
  • Chen, M., Si, L., Winzenberg, T., Gu, J., Jiang, Q. and Palmer, A. (2016), 'Cost-effectiveness of raloxifene in the treatment of osteoporosis in Chinese postmenopausal women : impact of medication persistence and adherence', Patient Preference and Adherence, vol 10 , pp 415 - 423.
  • Curry, B., Hitchens, P., Otahal, P., Si, L. and Palmer, A. (2016), 'Australian insurance costs of jockeys injured in a race-day fall', Occupational Medicine, vol 66, no 3 , pp 222 - 229.
  • de Graaff, B., Neil, A., Sanderson, K., Si, L., Yee, K. and Palmer, A. (2015), 'A systematic review and narrative synthesis of health economic studies conducted for hereditary haemochromatosis', Applied Health Economics and Health Policy, vol 13, no 5 , pp 469 - 483.
  • Si, L., Winzenberg, T., Chen, M., Jiang, Q. and Palmer, A. (2015), 'Residual lifetime and 10 year absolute risks of osteoporotic fractures in Chinese men and women', Current Medical Research and Opinion, vol 31, no 6 , pp 1149 - 1156.
  • Si, L., Winzenberg, T., Jiang, Q. and Palmer, A. (2015), 'Screening for and treatment of osteoporosis : construction and validation of a state-transition microsimulation cost-effectiveness model', Osteoporosis International, vol 26, no 5 , pp 1477 - 1489.
  • Si, L., Winzenberg, T., Jiang, Q., Chen, M. and Palmer, A. (2015), 'Projection of osteoporosis-related fractures and costs in China : 2010-2050', Osteoporosis International, vol 26, no 7 , pp 1929 - 1937.
  • Chen, M., Fang, G., Wang, L., Wang, Z., Zhao, Y. and Si, L. (2015), 'Who benefits from government healthcare subsidies? : an assessment of the equity of healthcare benefits distribution in China', PLoS One, vol 10, no 3 .
  • Si, L., Si, L. and Jiang, Q. (2015), 'Challenges to the Chinese health insurance system : users' and service providers' perspectives', Chinese Medical Journal, vol 128, no 5 , pp 571 - 573.
  • Curry, B., Hitchens, P., Otahal, P., Si, L. and Palmer, A. (2015), 'Workplace injuries in thoroughbred racing : an analysis of insurance payments and injuries amongst jockeys in Australia from 2002 to 2010', Animals, vol 5, no 3 , pp 897 - 909.
  • Palmer, A., Si, L., Gordon, J., Saul, T., Otahal, P. and Hitchens, P. (2015), 'Investigating the costs of major and minor cycling crashes in Tasmania, Australia', Australian and New Zealand Journal of Public Health, vol 39, no 5 , pp 485 - 490.
  • Chen, M., Zhao, Y. and Si, L. (2014), 'Who pays for health care in China? : the case of Heilongjiang Province', PLoS One, vol 9, no 10 .
  • Palmer, A., Si, L., Gordon, J., Saul, T., Curry, B., Otahal, P. and Hitchens, P. (2014), 'Accident rates amongst regular bicycle riders in Tasmania, Australia', Accident Analysis and Prevention, vol 72 , pp 376 - 381.
  • Si, L., Winzenberg, T. and Palmer, A. (2014), 'A systematic review of models used in cost-effectiveness analyses of preventing osteoporotic fractures', Osteoporosis International, vol 25, no 1 , pp 51 - 60.
  • Si, L., Winzenberg, T., de Graaff, B. and Palmer, A. (2014), 'A systematic review and meta-analysis of utility-based quality of life for osteoporosis-related conditions', Osteoporosis International, vol 25, no 8 , pp 1987 - 1997.
  • Lung, T., Hayes, A., Herman, W., Si, L., Palmer, A. and Clarke, P. (2014), 'A meta-analysis of the relative risk of mortality for Type 1 diabetes patients compared to the general population : exploring temporal changes in relative mortality', PLoS One, vol 9, no 11 .

Current Projects

Title: Building China-Australia co-operation in Health Technology Assessment (HTA) [via The George Institute for Global Health]
Funder:
  • Department of Foreign Affairs and Trade (Cat.1.5)
Western Researchers: Lei Si
Years: 2023-01-01 - 2025-05-31
ID: P00028361
Title: Cost-Effective Treatment and Management of Food Allergies in Australia [Via Murdoch Childrens Research Institute]
Funder:
  • Centre for Food Allergy Research
Western Researchers: Lei Si
Years: 2023-12-11 - 2026-12-10
ID: P00029071
Title: Responsible pre-operative Opioid use for Hip and knee ArthropLasTy (OpioidHALT) Study: Opioid tapering in patientsprior to hip and knee arthroplasty [via University of Sydney]
Funder:
  • National Health and Medical Research Council (ACRG)
Western Researchers: Lei Si
Years: 2023-02-01 - 2027-01-31
ID: P00028456

Supervision

Previous Supervision

Thesis Title: Harnessing Health Economics to Improve Management of Osteoporosis
Field of Research:
Thesis Title: Refractive Errors, Visual Impairment and Utilization of Spectacles Among Primary School Children in Onitsha, Anambra State, Nigeria
Field of Research:
Thesis Title: The impact of overweight and obesity on life expectancy and quality-adjusted life expectancy in the Chinese population.
Field of Research:

Media

Title: Osteoporosis-related fractures in China expected to double by 2035
Description: The results of the first study using a health economics model to project osteoporosis-related fractures and costs for the Chinese population, shows that the country's healthcare system will face a dramatic rise in costs over the next few decades.
Title: AHA names top advances in cardiovascular disease research for 2022
Description: A study from China, meanwhile, showed that the benefits of lower-sodium table salt extend beyond heart health. Prior research found that using a salt substitute could reduce the risk of stroke, heart attack and premature death among people in rural China who have a history of stroke or uncontrolled high blood pressure. In the new study, published in Circulation, researchers showed the salt substitute, containing 25% potassium chloride, lowered stroke risk and also saved people money by cutting health care costs. The authors conclude this strategy should be a priority in any country in which dietary sodium can be substantially reduced by use of a salt substitute. In contrast to people in the U.S., who eat a lot of processed food that includes high levels of sodium, the rural populations studied in China get most of their sodium from salt added to food in the home.

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