Professor Vaughan Macefield

Journal Articles

• Jeklin, A., Sully, F., Flannery, D., Naughton, M., Macefield, V., Nilsen, K., Ellis, M. and La Gerche, A. (2021), 'Exercise oscillatory ventilation during autonomic blockade in young athletes and healthy controls', European Journal of Applied Physiology, vol 121, no 9 , pp 2499 - 2507.
• Meylakh, N., Marciszewski, K., Di Pietro, F., Macefield, V., Macey, P. and Henderson, L. (2021), 'Brainstem functional oscillations across the migraine cycle : a longitudinal investigation', NeuroImage: Clinical, vol 30 .
• Taylor, C., Arnold, A., Fanciulli, A., Provini, F., Fu, Q., Macefield, V., Weese-Mayer, D., Shibao, C., Charkoudian, N. and Claydon, V. (2021), 'Women in clinical autonomic research and the autonomic societies : how far have we come in thirty years?', Clinical Autonomic Research, vol 31, no 1 , pp 23 - 26.
• Macefield, V. (2021), 'The roles of mechanoreceptors in muscle and skin in human proprioception', Current Opinion in Physiology, vol 21 , pp 48 - 56.
• Rankin, G., Kabele, M., Brown, R., Macefield, V., Sandstrom, T. and Bosson, J. (2021), 'Acute exposure to diesel exhaust increases muscle sympathetic nerve activity in humans', Journal of the American Heart Association, vol 10, no 10 .
• Corcoran, A., Macefield, V. and Hohwy, J. (2021), 'Be still my heart : cardiac regulation as a mode of uncertainty reduction', Psychonomic Bulletin and Review, vol 28, no 4 , pp 1211 - 1223.
• Macefield, V. (2021), 'Recording and quantifying sympathetic outflow to muscle and skin in humans : methods, caveats and challenges', Clinical Autonomic Research, vol 31, no 1 , pp 59 - 75.
• Boulton, D., Taylor, C., Green, S. and Macefield, V. (2021), 'The role of central command in the increase in muscle sympathetic nerve activity to contracting muscle during high intensity isometric exercise', Frontiers in Neuroscience, vol 15 .
• Sivathamboo, S., Friedman, D., Laze, J., Nightscales, R., Chen, Z., Kuhlmann, L., Devore, S., Macefield, V., Kwan, P., D'Souza, W., Berkovic, S., Perucca, P., O?Brien, T. and Devinsky, O. (2021), 'Association of short-term heart rate variability and sudden unexpected death in epilepsy', Neurology, vol 97, no 24 , pp 2357 - 2367.
• Powell, K., Liu, Z., Curl, C., Raaijmakers, A., Sharma, P., Braine, E., Gomes, F., Sivathamboo, S., Macefield, V., Casillas-Espinosa, P., Jones, N., Delbridge, L. and O'Brien, T. (2021), 'Altered cardiac structure and function is related to seizure frequency in a rat model of chronic acquired temporal lobe epilepsy', Neurobiology of Disease, vol 159 .
• Crawford, L., Mills, E., Hanson, T., Macey, P., Glarin, R., Macefield, V., Keay, K. and Henderson, L. (2021), 'Brainstem mechanisms of pain modulation : a within-subjects 7T fMRI study of placebo analgesic and nocebo hyperalgesic responses', Journal of Neuroscience, vol 41, no 47 , pp 9794 - 9806.
• Kobuch, S., Fatouleh, R., Macefield, J., Henderson, L. and Macefield, V. (2020), 'Differences in regional grey matter volume of the brain are related to mean blood pressure and muscle sympathetic nerve activity in normotensive humans', Journal of Hypertension, vol 38, no 2 , pp 303 - 313.
• Meylakh, N., Marciszewski, K., Di Pietro, F., Macefield, V., Macey, P. and Henderson, L. (2020), 'Altered regional cerebral blood flow and hypothalamic connectivity immediately prior to a migraine headache', Cephalalgia, vol 40, no 5 , pp 448 - 460.
• Foster, M., Singh, N., Kwok, K. and Macefield, V. (2020), 'Vestibular modulation of skin sympathetic nerve activity in sopite syndrome induced by low-frequency sinusoidal motion', Journal of Neurophysiology, vol 124, no 6 , pp 1551 - 1559.
• Smith, L., Norcliffe-Kaufmann, L., Palma, J., Kaufmann, H. and Macefield, V. (2020), 'Elbow proprioception is normal in patients with a congenital absence of functional muscle spindles', Journal of Physiology, vol 598, no 16 , pp 3521 - 3529.
• Mungoven, T., Meylakh, N., Marciszewski, K., Macefield, V., Macey, P. and Henderson, L. (2020), 'Microstructural changes in the trigeminal nerve of patients with episodic migraine assessed using magnetic resonance imaging', Journal of Headache and Pain, vol 21, no 1 .
• Sivathamboo, S., Constantino, T., Chen, Z., Sparks, P., Goldin, J., Velakoulis, D., Jones, N., Kwan, P., Macefield, V., O'Brien, T. and Perucca, P. (2020), 'Cardiorespiratory and autonomic function in epileptic seizures : a video-EEG monitoring study', Epilepsy and Behavior, vol 111 .
• Grotle, A., Macefield, V., Farquhar, W., O'Leary, D. and Stone, A. (2020), 'Recent advances in exercise pressor reflex function in health and disease', Autonomic Neuroscience: Basic and Clinical, vol 228 .
• Ottaviani, M., Wright, L., Dawood, T. and Macefield, V. (2020), 'In vivo recordings from the human vagus nerve using ultrasound-guided microneurography', Journal of Physiology, vol 598, no 17 , pp 3569 - 3576.
• Abu Serdaneh, S., AlHalabi, M., Kowash, M., Macefield, V., Khamis, A., Salami, A. and Hussein, I. (2020), 'Hall technique crowns and children's masseter muscle activity : a surface electromyography pilot study', International Journal of Paediatric Dentistry, vol 30, no 3 , pp 303 - 313.
• Kobuch, S., Macefield, V. and Henderson, L. (2019), 'Resting regional brain activity and connectivity vary with resting blood pressure but not muscle sympathetic nerve activity in normotensive humans : an exploratory study', Journal of Cerebral Blood Flow and Metabolism, vol 39, no 12 , pp 2433 - 2444.
• Knellwolf, T., Burton, A., Hammam, E. and Macefield, V. (2019), 'Firing properties of muscle spindles supplying the intrinsic foot muscles of humans in unloaded and free-standing conditions', Journal of Neurophysiology, vol 121, no 1 , pp 74 - 84.
• Smith, L., Macefield, V., Birznieks, I. and Burton, A. (2019), 'Effects of tonic muscle pain on fusimotor control of human muscle spindles during isometric ankle dorsiflexion', Journal of Neurophysiology, vol 121, no 4 , pp 1143 - 1149.
• Singh, N., Hammam, E. and Macefield, V. (2019), 'Vestibular modulation of muscle sympathetic nerve activity assessed over a 100-fold frequency range of sinusoidal galvanic vestibular stimulation', Journal of Neurophysiology, vol 121, no 5 , pp 1644 - 1649.
• Boulton, D., Green, S., Macefield, V. and Taylor, C. (2019), 'A comparison of muscle sympathetic nerve activity to non-contracting muscle during isometric exercise in the upper and lower limbs', Frontiers in Neuroscience, vol 13 .
• Marciszewski, K., Meylakh, N., Di Pietro, F., Macefield, V., Macey, P. and Henderson, L. (2019), 'Fluctuating regional brainstem diffusion imaging measures of microstructure across the migraine cycle', eNeuro, vol 6, no 4 .
• Birznieks, I., McIntyre, S., Nilsson, H., Nagi, S., Macefield, V., Mahns, D. and Vickery, R. (2019), 'Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type', eLife, vol 8 .
• Campos, M., Mansur, D., Mattos, J., Paiva, A., Videira, R., Macefield, V., Nobrega, A. and Fernandes, I. (2019), 'Acid-sensing ion channels blockade attenuates pressor and sympathetic responses to skeletal muscle metaboreflex activation in humans', Journal of Applied Physiology, vol 127, no 5 , pp 1491 - 1501.
• Javaid, A., Chouhna, H., Varghese, B., Hammam, E. and Macefield, V. (2019), 'Changes in skin blood flow, respiration and blood pressure in participants reporting motion sickness during sinusoidal galvanic vestibular stimulation', Experimental Physiology, vol 104, no 11 , pp 1622 - 1629.
• Hissen, S., Macefield, V., Brown, R. and Taylor, C. (2019), 'Sympathetic baroreflex sensitivity is inversely related to vascular transduction in men but not women', American Journal of Physiology: Heart and Circulatory Physiology, vol 317, no 6 , pp 1203 - 1209.
• Macefield, V. and Henderson, L. (2019), 'Identification of the human sympathetic connectome involved in blood pressure regulation', NeuroImage, vol 202 .
• Mansur, D., Campos, M., Mattos, J., Paiva, A., Rocha, M., Videira, R., Macefield, V., Nobrega, A. and Fernandes, I. (2019), 'Muscle sympathetic nerve activity and hemodynamic responses to venous distension : does sex play a role?', American Journal of Physiology: Heart and Circulatory Physiology, vol 316, no 3 , pp 734 - 742.
• Marciszewski, K., Meylakh, N., Di Pietro, F., Macefield, V., Macey, P. and Henderson, L. (2018), 'Altered brainstem anatomy in migraine', Cephalalgia, vol 38, no 3 , pp 476 - 486.
• Brown, R., Burton, A. and Macefield, V. (2018), 'Autonomic dysreflexia : somatosympathetic and viscerosympathetic vasoconstrictor responses to innocuous and noxious sensory stimulation below lesion in human spinal cord injury', Autonomic Neuroscience: Basic and Clinical, vol 209 , pp 71 - 78.
• Macefield, V. and Wallin, B. (2018), 'Physiological and pathophysiological firing properties of single postganglionic sympathetic neurons in humans', Journal of Neurophysiology, vol 119, no 3 , pp 944 - 956.
• Bolton, P., Hammam, E. and Macefield, V. (2018), 'Neck movement but not neck position modulates skin sympathetic nerve activity supplying the lower limbs of humans', Journal of Neurophysiology, vol 119, no 4 , pp 1283 - 1290.
• Kobuch, S., Fazalbhoy, A., Brown, R., Macefield, V. and Henderson, L. (2018), 'Muscle sympathetic nerve activity-coupled changes in brain activity during sustained muscle pain', Brain and Behavior, vol 8, no 3 .
• Boulton, D., Taylor, C., Green, S. and Macefield, V. (2018), 'The metaboreflex does not contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans', Journal of Physiology, vol 596, no 6 , pp 1091 - 1102.
• Macefield, V. and Knellwolf, T. (2018), 'Functional properties of human muscle spindles', Journal of Neurophysiology, vol 120, no 2 , pp 452 - 467.
• Kobuch, S., Henderson, L., Macefield, V. and Brown, R. (2018), 'The effects of audiovisual distraction on the muscle sympathetic responses to experimental muscle pain', Experimental Brain Research, vol 236, no 7 , pp 1919 - 1925.
• Knellwolf, T., Burton, A., Hammam, E. and Macefield, V. (2018), 'Microneurography from the posterior tibial nerve : a novel method of recording activity from the foot in freely standing humans', Journal of Neurophysiology, vol 120, no 3 , pp 953 - 959.
• Hissen, S., El Sayed, K., Macefield, V., Brown, R. and Taylor, C. (2018), 'The stability and repeatability of spontaneous sympathetic baroreflex sensitivity in healthy young individuals', Frontiers in Neuroscience, vol 12 .
• Hammam, E., Knellwolf, T., Wong, K., Kwok, K. and Macefield, V. (2018), 'Random-amplitude sinusoidal linear acceleration causes greater vestibular modulation of skin sympathetic nerve activity than constant-amplitude acceleration', Experimental Brain Research, vol 236, no 10 , pp 2619 - 2626.
• Meylakh, N., Marciszewski, K., Di Pietro, F., Macefield, V., Macey, P. and Henderson, L. (2018), 'Deep in the brain : changes in subcortical function immediately preceding a migraine attack', Human Brain Mapping, vol 39, no 6 , pp 2651 - 2663.
• Smith, L., Norcliffe-Kaufmann, L., Palma, J., Kaufman, H. and Macefield, V. (2018), 'Impaired sensorimotor control of the hand in congenital absence of functional muscle spindles', Journal of Neurophysiology, vol 120, no 6 , pp 2788 - 2795.
• El Sayed, K., Macefield, V., Hissen, S., Joyner, M. and Taylor, C. (2018), 'Blood pressure reactivity at onset of mental stress determines sympathetic vascular response in young adults', Physiological Reports, vol 6, no 24 .
• Marciszewski, K., Meylakh, N., Di Pietro, F., Mills, E., Macefield, V., Macey, P. and Henderson, L. (2018), 'Changes in brainstem pain modulation circuitry function over the migraine cycle', Journal of Neuroscience, vol 38, no 49 , pp 10479 - 10488.
• Di Pietro, F., Macey, P., Rae, C., Alshelh, Z., Macefield, V., Vickers, E. and Henderson, L. (2018), 'The relationship between thalamic GABA content and resting cortical rhythm in neuropathic pain', Human Brain Mapping, vol 39, no 5 , pp 1945 - 1956.
• Gutierrez, J., Kaufmann, H., Palma, J., Mendoza-Santiesteban, C., Macefield, V. and Norcliffe-Kaufmann, L. (2018), 'Founder mutation in IKBKAP gene causes vestibular impairment in familial dysautonomia', Clinical Neurophysiology, vol 129, no 2 , pp 390 - 396.
• Leitch, M. and Macefield, V. (2017), 'Comparison of the ballistic contractile responses generated during microstimulation of single human motor axons with brief irregular and regular stimuli', Muscle and Nerve, vol 56, no 2 , pp 292 - 297.
• Kobuch, S., Fazalbhoy, A., Brown, R., Henderson, L. and Macefield, V. (2017), 'Central circuitry responsible for the divergent sympathetic responses to tonic muscle pain in humans', Human Brain Mapping, vol 38, no 2 , pp 869 - 881.
• Day, J., Bent, L., Birznieks, I., Macefield, V. and Cresswell, A. (2017), 'Muscle spindles in human tibialis anterior encode muscle fascicle length changes', Journal of Neurophysiology, vol 117, no 4 , pp 1489 - 1498.
• Fontes, M., Filho, M., Machado, N., Paula, C., Cordeiro, L., Xavier, C., Marins, F., Henderson, L. and Macefield, V. (2017), 'Asymmetric sympathetic output : the dorsomedial hypothalamus as a potential link between emotional stress and cardiac arrhythmias', Autonomic Neuroscience, vol 207 , pp 22 - 27.
• Chen, D., Brown, R., Liess, C., Poljak, A., Xu, A., Zhang, J., Trenell, M., Jenkins, A., Chisholm, D., Samocha-Bonet, D., Macefield, V. and Greenfield, J. (2017), 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, vol 8 .
• Leitch, M. and Macefield, V. (2017), 'Microstimulation of single human motor axons in the toe extensors : force production during long-lasting trains of irregular and regular stimuli', Physiological Reports, vol 5, no 4 .
• Hissen, S., El Sayed, K., Macefield, V., Brown, R. and Taylor, C. (2017), 'Muscle sympathetic nerve activity peaks in the first trimester in healthy pregnancy : a longitudinal case study', Clinical Autonomic Research, vol 27, no 6 , pp 401 - 406.
• Hammam, E. and Macefield, V. (2017), 'Vestibular modulation of sympathetic nerve activity to muscle and skin in humans', Frontiers in Neurology, vol 8 .
• Martin Monzon, B., Henderson, L., Madden, S., Macefield, V., Touyz, S., Kohn, M., Clarke, S., Foroughi, N. and Hay, P. (2017), 'Grey matter volume in adolescents with anorexia nervosa and associated eating disorder symptoms', European Journal of Neuroscience, vol 46, no 7 , pp 2297 - 2307.
• Leitch, M., Brown, R. and Macefield, V. (2017), 'Intramuscular stimulation of tibialis anterior in human subjects : the effects of discharge variability on force production and fatigue', Physiological Reports, vol 5, no 15 , pp 1 - 7.
• Youssef, A., Macefield, V. and Henderson, L. (2016), 'Pain inhibits pain : human brainstem mechanisms', NeuroImage, vol 124, no Part A , pp 54 - 62.
• Bolton, P., Hammam, E., Kwok, K. and Macefield, V. (2016), 'Skin sympathetic nerve activity is modulated during slow sinusoidal linear displacements in supine humans', Frontiers in Neuroscience, vol 10 .
• Macefield, V., Norcliffe-Kaufmann, L., Goulding, N., Palma, J., Fuente Mora, C. and Kaufmann, H. (2016), 'Increasing cutaneous afferent feedback improves proprioceptive accuracy at the knee in patients with sensory ataxia', Journal of Neurophysiology, vol 115, no 2 , pp 711 - 716.
• Henderson, L., Fatouleh, R., Lundblad, L., McKenzie, D. and Macefield, V. (2016), 'Effects of 12 months continuous positive airway pressure on sympathetic activity related brainstem function and structure in obstructive sleep apnea', Frontiers in Neuroscience, vol 10, no 90 .
• Brown, R., Celermajer, D., Macefield, V. and Sander, M. (2016), 'The effect of nitric oxide inhibition in spinal cord injured humans with and without preserved sympathetic control of the vasculature', Frontiers in Neuroscience, vol 10, no MAR , pp 65 - 65.
• Knellwolf, T., Hammam, E. and Macefield, V. (2016), 'The vestibular system does not modulate fusimotor drive to muscle spindles in relaxed leg muscles of subjects in a near-vertical position', Journal of Neurophysiology, vol 115, no 5 , pp 2529 - 2535.
• Youssef, A., Macefield, V. and Henderson, L. (2016), 'Cortical influences on brainstem circuitry responsible for conditioned pain modulation in humans', Human Brain Mapping, vol 37, no 7 , pp 2630 - 2644.
• Henderson, L. and Macefield, V. (2016), 'Obstructive sleep apnoea and hypertension : the role of the central nervous system', Current Hypertension Reports, vol 18, no 7 , pp 59 - .
• Kobuch, S., Fazalbhoy, A., Brown, R. and Macefield, V. (2016), 'Inter-individual responses to experimental muscle pain : baseline anxiety ratings and attitudes to pain do not determine the direction of the sympathetic response to tonic muscle pain in humans', International Journal of Psychophysiology, vol 104 , pp 17 - 23.
• Macefield, V. and Henderson, L. (2016), 'Real-time imaging of cortical and subcortical sites of cardiovascular control: concurrent recordings of sympathetic nerve activity and fMRI in awake subjects', Journal of Neurophysiology, vol 116, no 3 , pp 1199 - 1207.
• Wright, J., Macefield, V., van Schaik, A. and Tapson, J. (2016), 'A review of control strategies in closed-loop neuroprosthetic systems', Frontiers in Neuroscience, vol 10 , pp 312 - .
• Burton, A., Fazalbhoy, A. and Macefield, V. (2016), 'Sympathetic responses to noxious stimulation of muscle and skin', Frontiers in Neurology, vol 7 .
• Boulton, D., Taylor, C., Macefield, V. and Green, S. (2016), 'Contributions of central command and muscle feedback to sympathetic nerve activity in contracting human skeletal muscle', Frontiers in Physiology, vol 7 .
• Lamb, S., Macefield, V., Walton, D. and Kwok, K. (2016), 'Occupant response to wind-excited buildings : a multidisciplinary perspective', Proceedings of the Institution of Civil Engineers: Structures and Buildings, vol 169, no 8 , pp 625 - 634.
• Johnson, A., Hissen, S., Macefield, V., Brown, R. and Taylor, C. (2016), 'Magnitude of morning surge in blood pressure is associated with sympathetic but not cardiac baroreflex sensitivity', Frontiers in Neuroscience, vol 10, no 412 , pp 1 - 10.
• Macefield, V. and James, C. (2016), 'Superentrainment of muscle sympathetic nerve activity during sinusoidal galvanic vestibular stimulation', Journal of Neurophysiology, vol 116, no 6 , pp 2689 - 2694.
• El Sayed, K., Macefield, V., Hissen, S., Joyner, M. and Taylor, C. (2016), 'Rate of rise in diastolic blood pressure influences vascular sympathetic response to mental stress', Journal of Physiology, vol 594, no 24 , pp 7465 - 7482.
• Fatouleh, R., Lundblad, L., Macey, P., McKenzie, D., Henderson, L. and Macefield, V. (2015), 'Reversal of functional changes in the brain associated with obstructive sleep apnoea following 6 months of CPAP', NeuroImage: Clinical, vol 7 , pp 799 - 806.
• Lee, M., Kiernan, M., Macefield, V., Lee, B. and Lin, C. (2015), 'Short-term peripheral nerve stimulation ameliorates axonal dysfunction after spinal cord injury', Journal of Neurophysiology, vol 113, no 9 , pp 3209 - 3218.
• Macefield, V. and Henderson, L. (2015), 'Autonomic responses to exercise : cortical and subcortical responses during post-exercise ischaemia and muscle pain', Autonomic Neuroscience: Basic and Clinical, vol 188 , pp 10 - 18.
• Macefield, V. and Walton, D. (2015), 'Susceptibility to motion sickness is not increased following spinal cord injury', Journal of Vestibular Research: Equilibrium and Orientation, vol 25, no 1 , pp 35 - 39.
• Leitch, M. and Macefield, V. (2015), 'Comparison of contractile responses of single human motor units in the toe extensors during unloaded and loaded isotonic and isometric conditions', Journal of Neurophysiology, vol 114, no 2 , pp 1083 - 1089.
• Klingberg, D., Hammam, E. and Macefield, V. (2015), 'Motion sickness is associated with an increase in vestibular modulation of skin but not muscle sympathetic nerve activity', Experimental Brain Research, vol 233, no 8 , pp 2433 - 2440.
• Hissen, S., Macefield, V., Brown, R., Witter, T. and Taylor, C. (2015), 'Baroreflex modulation of muscle sympathetic nerve activity at rest does not differ between morning and afternoon', Frontiers in Neuroscience, vol 9 .
• Hudson, K., Condon, M., Ackerley, R., McGlone, F., Olausson, H., Macefield, V. and Birznieks, I. (2015), 'Effects of changing skin mechanics on the differential sensitivity to surface compliance by tactile afferents in the human finger pad', Journal of Neurophysiology, vol 114, no 4 , pp 2249 - 2257.
• Kobuch, S., Fazalbhoy, A., Brown, R. and Macefield, V. (2015), 'Inter-individual responses to experimental muscle pain : baseline physiological parameters do not determine whether muscle sympathetic nerve activity increases or decreases during pain', Frontiers in Neuroscience, vol 9 .
• Taylor, C., Witter, T., El Sayed, K., Hissen, S., Johnson, A. and Macefield, V. (2015), 'Relationship between spontaneous sympathetic baroreflex sensitivity and cardiac baroreflex sensitivity in healthy young individuals', Physiological Reports, vol 3, no 11 .
• Hammam, E., Hau, C., Wong, K., Kwok, K. and Macefield, V. (2014), 'Vestibular modulation of muscle sympathetic nerve activity by the utricle during sub-perceptual sinusoidal linear acceleration in humans', Experimental Brain Research, vol 232, no 4 , pp 1379 - 1388.
• Boulton, D., Taylor, C., Macefield, V. and Green, S. (2014), 'Effect of contraction intensity on sympathetic nerve activity to active human skeletal muscle', Frontiers in Physiology, vol 5 , pp 1 - 9.
• Brown, R. and Macefield, V. (2014), 'Skin sympathetic nerve activity in humans during exposure to emotionally-charged images : sex differences', Frontiers in Physiology, vol 5 .
• Fazalbhoy, A., Birznieks, I. and Macefield, V. (2014), 'Consistent interindividual increases or decreases in muscle sympathetic nerve activity during experimental muscle pain', Experimental Brain Research, vol 232, no 4 , pp 1309 - 1315.
• Leitch, M. and Macefield, V. (2014), 'Comparison of the contractile responses to irregular and regular trains of stimuli during microstimulation of single human motor axons', Journal of Neurophysiology, vol 111, no 7 , pp 1499 - 1506.
• Condon, M., Birznieks, I., Hudson, K., Chelvanayagam, D., Mahns, D., Olausson, H. and Macefield, V. (2014), 'Differential sensitivity to surface compliance by tactile afferents in the human finger pad', Journal of Neurophysiology, vol 111, no 6 , pp 1308 - 1317.
• Bolton, P., Hammam, E. and Macefield, V. (2014), 'Neck proprioceptors contribute to the modulation of muscle sympathetic nerve activity to the lower limbs of humans', Experimental Brain Research, vol 232, no 7 , pp 2263 - 2271.
• Macefield, V., Norcliffe-Kaufmann, L., Loken, L., Axelrod, F. and Kaufmann, H. (2014), 'Disturbances in affective touch in hereditary sensory & autonomic neuropathy type III', International Journal of Psychophysiology, vol 93, no 1 , pp 56 - 61.
• Wallin, B., Karlsson, T., Pegenius, G., Karlsson, A., Macefield, V. and Elam, M. (2014), 'Sympathetic single axonal discharge after spinal cord injury in humans : activity at rest and after bladder stimulation', Spinal Cord, vol 52, no 6 , pp 434 - 438.
• Hammam, E., Bolton, P., Kwok, K. and Macefield, V. (2014), 'Vestibular modulation of muscle sympathetic nerve activity during sinusoidal linear acceleration in supine humans', Frontiers in Neuroscience, vol 8 .
• Fatouleh, R., McKenzie, D. and Macefield, V. (2014), 'Respiratory modulation of muscle sympathetic nerve activity in obstructive sleep apnoea', Experimental Physiology, vol 99, no 10 , pp 1288 - 1298.
• Arabzadeh, E., Clifford, C., Harris, J., Mahns, D., Macefield, V. and Birznieks, I. (2014), 'Single tactile afferents outperform human subjects in a vibrotactile intensity discrimination task', Journal of Neurophysiology, vol 112, no 10 , pp 2382 - 2387.
• Lundblad, L., Fatouleh, R., Hammam, E., McKenzie, D., Macefield, V. and Henderson, L. (2014), 'Brainstem changes associated with increased muscle sympathetic drive in obstructive sleep apnoea', NeuroImage, vol 103 , pp 258 - 266.
• Fatouleh, R., Hammam, E., Lundblad, L., Macey, P., McKenzie, D., Henderson, L. and Macefield, V. (2014), 'Functional and structural changes in the brain associated with the increase in muscle sympathetic nerve activity in obstructive sleep apnoea', NeuroImage: Clinical, vol 6 , pp 275 - 283.
• Yates, B., Bolton, P. and Macefield, V. (2014), 'Vestibulo-sympathetic responses', Comprehensive Physiology, vol 4, no 2 , pp 851 - 887.
• Seitz, M., Brown, R. and Macefield, V. (2013), 'Inhibition of augmented muscle vasoconstrictor drive following asphyxic apnoea in awake human subjects is not affected by relief of chemical drive', Experimental Physiology, vol 98, no 2 , pp 405 - 414.
• Macefield, V. (2013), 'Discharge rates and discharge variability of muscle spindle afferents in human chronic spinal cord injury', Clinical Neurophysiology, vol 124, no 1 , pp 114 - 119.
• Macefield, V., Norcliffe-Kaufmann, L., Axelrod, F. and Kaufmann, H. (2013), 'Cardiac-locked bursts of muscle sympathetic nerve activity are absent in familial dysautonomia', Journal of Physiology, vol 591, no 3 , pp 689 - 700.
• James, C., Macefield, V. and Henderson, L. (2013), 'Real-time imaging of cortical and subcortical control of muscle sympathetic nerve activity in awake human subjects', Neuroimage, vol 70 , pp 59 - 65.
• Wallin, B., Burton, A., Elam, M., Tamaddon, K., Millard, R. and Macefield, V. (2013), 'Viscerosympathetic reflexes in human spinal cord injury : relationships between detrusor pressure, blood pressure and skin blood flow during bladder distension', Experimental Physiology, vol 98, no 6 , pp 1081 - 1091.
• Fazalbhoy, A., Macefield, V. and Birznieks, I. (2013), 'Tonic muscle pain does not increase fusimotor drive to human leg muscles : implications for chronic muscle pain', Experimental Physiology, vol 98, no 6 , pp 1125 - 1132.
• James, C., Henderson, L. and Macefield, V. (2013), 'Real-time imaging of brain areas involved in the generation of spontaneous skin sympathetic nerve activity at rest', NeuroImage, vol 74 , pp 188 - 194.
• Fatouleh, R. and Macefield, V. (2013), 'Cardiorespiratory coupling of sympathetic outflow in humans : a comparison of respiratory and cardiac modulation of sympathetic nerve activity to skin and muscle', Experimental Physiology, vol 98, no 9 , pp 1327 - 1336.
• Macefield, V., Norcliffe-Kaufmann, L., Axelrod, F. and Kaufmann, H. (2013), 'Relationship between proprioception at the knee joint and gait ataxia in HSAN III', Movement Disorders, vol 28, no 6 , pp 823 - 827.
• Hammam, E., Kwok, K. and Macefield, V. (2013), 'Modulation of muscle sympathetic nerve activity by low-frequency physiological activation of the vestibular utricle in awake humans', Experimental Brain Research, vol 230, no 1 , pp 137 - 142.
• Bent, L., Sander, M., Bolton, P. and Macefield, V. (2013), 'The vestibular system does not modulate fusimotor drive to muscle spindles in contracting leg muscles of seated subjects', Experimental Brain Research, vol 227, no 2 , pp 175 - 183.
• Brown, R., Kemp, U. and Macefield, V. (2013), 'Increases in muscle sympathetic nerve activity, heart rate, respiration, and skin blood flow during passive viewing of exercise', Frontiers in Neuroscience, vol 7, no 102 , pp 1 - 6.
• Henderson, L. and Macefield, V. (2013), 'Functional imaging of the human brainstem during somatosensory input and autonomic output', Frontiers in Human Neuroscience, vol 7, no SEP .
• Macefield, V., James, C. and Henderson, L. (2013), 'Identification of sites of sympathetic outflow at rest and during emotional arousal : concurrent recordings of sympathetic nerve activity and fMRI of the brain', International Journal of Psychophysiology, vol 89, no 3 , pp 451 - 459.
• Brown, R., Duma, S., Piguet, O., Broe, A. and Macefield, V. (2012), 'Cardiovascular variability in Parkinson's disease and extrapyramidal motor slowing', Clinical Autonomic Research, vol 22, no 4 , pp 191 - 196.
• Chan, G., Fazalbhoy, A., Birznieks, I., Macefield, V., Middleton, P. and Lovell, N. (2012), 'Spontaneous fluctuations in the peripheral photoplethysmographic waveform : roles of arterial pressure and muscle sympathetic nerve activity', American Journal of Physiology: Heart and Circulatory Physiology, vol 302, no 3 , pp 826 - 836.
• Hall, S., Fazalbhoy, A., Birznieks, I. and Macefield, V. (2012), 'Biphasic effects of tonic stimulation of muscle nociceptors on skin sympathetic nerve activity in human subjects', Experimental Brain Research, vol 221, no 1 , pp 107 - 114.
• Grewal, T., Dawood, T., Hammam, E., Kwok, K. and Macefield, V. (2012), 'Low-frequency physiological activation of the vestibular utricle causes biphasic modulation of skin sympathetic nerve activity in humans', Experimental Brain Research, vol 220, no 2 , pp 101 - 108.
• Birznieks, I., Boonstra, T. and Macefield, V. (2012), 'Modulation of human muscle spindle discharge by arterial pulsations : functional effects and consequences', PLoS One, vol 7, no 4 .
• Henderson, L., James, C. and Macefield, V. (2012), 'Identification of sites of sympathetic outflow during concurrent recordings of sympathetic nerve activity and fMRI', Anatomical Record, vol 295, no 9 , pp 1396 - 1403.
• Henderson, L., Stathis, A., James, C., Brown, R., McDonald, S. and Macefield, V. (2012), 'Real-time imaging of cortical areas involved in the generation of increases in skin sympathetic nerve activity when viewing emotionally charged images', NeuroImage, vol 62, no 1 , pp 30 - 40.
• El Sayed, K., Dawood, T., Hammam, E. and Macefield, V. (2012), 'Evidence from bilateral recordings of sympathetic nerve activity for lateralisation of vestibular contributions to cardiovascular control', Experimental Brain Research, vol 221, no 4 , pp 427 - 436.
• Fazalbhoy, A., Birznieks, I. and Macefield, V. (2012), 'Individual differences in the cardiovascular responses to tonic muscle pain : parallel increases or decreases in muscle sympathetic nerve activity, blood pressure and heart rate', Experimental Physiology, vol 97, no 10 , pp 1084 - 1092.
• Macefield, V. (2012), 'Firing patterns of muscle vasoconstrictor neurons in respiratory disease', Frontiers in Physiology, vol 3, no MAY .
• Macefield, V., Burton, A. and Brown, R. (2012), 'Somatosympathetic vasoconstrictor reflexes in human spinal cord injury : responses to innocuous and noxious sensory stimulation below lesion', Frontiers in Physiology, vol 3 .
• Brown, R., James, C., Henderson, L. and Macefield, V. (2012), 'Autonomic markers of emotional processing : skin sympathetic nerve activity in humans during exposure to emotionally charged images', Frontiers in Physiology, vol 3, no 1 , pp 1 - 6.
• Hammam, E., Dawood, T. and Macefield, V. (2012), 'Low-frequency galvanic vestibular stimulation evokes two peaks of modulation in skin sympathetic nerve activity', Experimental Brain Research, vol 219, no 4 , pp 441 - 446.
• Henderson, L., Rubin, T. and Macefield, V. (2011), 'Within-limb somatotopic representation of acute muscle pain in the human contralateral dorsal posterior insula', Human Brain Mapping, vol 32, no 10 , pp 1592 - 1601.
• Macefield, V. (2011), 'On the number of preganglionic neurons driving human postganglionic sympathetic neurons : a comparison of modeling and empirical data', Frontiers in Neuroscience, vol 5, no 132 , pp 1 - 6.
• Macefield, V., Norcliffe-Kaufmann, L., Gutierrez, J., Axelrod, F. and Kaufmann, H. (2011), 'Can loss of muscle spindle afferents explain the ataxic gait in Riley-Day syndrome?', Brain, vol 134, no 11 , pp 3198 - 3208.
• Fatouleh, R. and Macefield, V. (2011), 'Respiratory modulation of muscle sympathetic nerve activity is not increased in essential hypertension or chronic obstructive pulmonary disease', Journal of Physiology, vol 589, no 20 , pp 4997 - 5006.
• Hammam, E., James, C., Dawood, T. and Macefield, V. (2011), 'Low-frequency sinusoidal galvanic stimulation of the left and right vestibular nerves reveals two peaks of modulation in muscle sympathetic nerve activity', Experimental Brain Research, vol 213, no 4 , pp 507 - 514.
• Nagi, S., Rubin, T., Chelvanayagam, D., Macefield, V. and Mahns, D. (2011), 'Allodynia mediated by C-tactile afferents in human hairy skin', Journal of Physiology, vol 589, no 16 , pp 4065 - 4075.
• Macefield, V. and Henderson, L. (2010), 'Real-time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake subjects', Human Brain Mapping, vol 31, no 4 , pp 539 - 549.
• Ashley, C., Burton, D., Sverrisdottir, Y., Sander, M., Mckenzie, D. and Macefield, V. (2010), 'Firing probability and mean firing rates of human muscle vasoconstrictor neurones are elevated during chronic asphyxia', The Journal of Physiology, vol 588, no 4 , pp 701 - 711.
• Sander, M., Macefield, V. and Henderson, L. (2010), 'Cortical and brain stem changes in neural activity during static handgrip and post-exercise ischemia in humans', Journal of Applied Physiology, vol 108, no 6 , pp 1691 - 1700.
• Rubin, T., Henderson, L. and Macefield, V. (2010), 'Changes in the spatiotemporal expression of local and referred pain following repeated intramuscular injections of hypertonic saline : a longtitudinal study', The Journal of Pain, vol 11, no 8 , pp 737 - 745.
• James, C., Stathis, A. and Macefield, V. (2010), 'Vestibular and pulse-related modulation of skin sympathetic nerve activity during sinusoidal galvanic vestibular stimulation in human subjects', Experimental Brain Research, vol 202, no 2 , pp 291 - 298.
• James, C. and Macefield, V. (2010), 'Competitive interactions between vestibular and cardiac rhythms in the modulation of muscle sympathetic nerve activity', Autonomic Neuroscience: Basic and Clinical, vol 158, no 40575 , pp 127 - 131.
• Nash, P., Macefield, V., Klineberg, I., Gustin, S., Murray, G. and Henderson, L. (2010), 'Changes in human primary motor cortex activity during acute cutaneous and muscle orofacial pain', Journal of Orofacial Pain, vol 24, no 4 , pp 379 - 390.
• Nash, P., Macefield, V., Klineberg, I., Gustin, S., Murray, G. and Henderson, L. (2010), 'Bilateral activation of the trigeminothalamic tract by acute orofacial cutaneous and muscle pain in humans', Pain, vol 151, no 2 , pp 384 - 393.
• Wrigley, P., Press, S., Gustin, S., Macefield, V., Gandevia, S., Cousins, M., Middleton, J., Henderson, L. and Siddall, P. (2009), 'Neuropathic pain and primary somatosensory cortex reorganisation following spinal cord injury', Pain, vol 141, no 1-2 , pp 52 - 59.
• Burton, A., Birznieks, I., Bolton, P., Henderson, L. and Macefield, V. (2009), 'Effects of deep and superficial experimentally induced acute pain on muscle sympathetic nerve activity in human subjects', Journal of Physiology, vol 587, no 1 , pp 183 - 193.
• Wrigley, P., Gustin, S., Macey, P., Nash, P., Gandevia, S., Macefield, V., Siddall, P. and Henderson, L. (2009), 'Anatomical changes in human motor cortex and motor pathways following complete thoracic spinal cord injury', Cerebral Cortex, vol 19, no 1 , pp 224 - 232.
• Rubin, T., Gandevia, S., Henderson, L. and Macefield, V. (2009), 'Effects of Intramuscular Anesthesia on the Expression of Primary and Referred Pain Induced by Intramuscular Injection of Hypertonic Saline', Journal of Pain, vol 10, no 8 , pp 829 - 835.
• Birznieks, I., Macefield, V., Westling, G. and Johansson, R. (2009), 'Slowly adapting mechanoreceptors in the borders of the human fingernail encode fingertip forces', Journal of Neuroscience, vol 29, no 29 , pp 9370 - 9379.
• Nash, P., Macefield, V., Klineberg, I., Murray, G. and Henderson, L. (2009), 'Differential activation of the human trigeminal nuclear complex by noxious and non-noxious orofacial stimulation', Human Brain Mapping, vol 30, no 11 , pp 3772 - 3782.
• Grewal, T., James, C. and Macefield, V. (2009), 'Frequency-dependent modulation of muscle sympathetic nerve activity by sinusoidal galvanic vestibular stimulation in human subjects', Experimental Brain Research, vol 197, no 4 , pp 379 - 386.
• Brown, R., Burton, A. and Macefield, V. (2009), 'Input-output relationships of a somatosympathetic reflex in human spinal injury', Clinical Autonomic Research, vol 19, no 4 , pp 213 - 220.
• Brown, R., Stolzenhein, G., Engel, S. and Macefield, V. (2009), 'Cutaneous vasoconstriction as a measure of incipient autonomic dysreflexia during penile vibratory stimulation in spinal cord injury', Spinal Cord, vol 47, no 7 , pp 538 - 544.
• Burton, A., Birznieks, I., Spaak, J., Henderson, L. and Macefield, V. (2009), 'Effects of deep and superficial experimentally induced acute pain on skin sympathetic nerve activity in human subjects', Experimental Brain Research, vol 195, no 2 , pp 317 - 324.
• Mcnulty, P., Galea, V., Fallon, J., Bent, L. and Macefield, V. (2008), 'Low threshold afferent signalling of viscous loads during voluntary movements of the human digits', Neuroreport, vol 19, no 10 , pp 1049 - 1054.
• Birznieks, I., Burton, A. and Macefield, V. (2008), 'The effects of experimental muscle and skin pain on the static stretch sensitivity of human muscle spindles in relaxed leg muscles', The Journal of Physiology, vol 586, no 11 , pp 2713 - 2723.
• Brown, R. and Macefield, V. (2008), 'Assessing the capacity of the sympathetic nervous system to respond to a cardiovascular challenge in human spinal cord injury', Spinal Cord, vol 46, no 10 , pp 666 - 672.
• Burton, A., Brown, R. and Macefield, V. (2008), 'Selective activation of muscle and skin nociceptors does not trigger exaggerated sympathetic responses in spinal-injured subjects', Spinal Cord, vol 46, no 10 , pp 660 - 665.
• Macefield, V., Sverrisdottir, Y., Elam, M. and Harris, J. (2008), 'Firing properties of sudomotor neurones in hyperhidrosis and thermal sweating', Clinical Autonomic Research, vol 18, no 6 , pp 325 - 330.
• Brown, R., Stolzenheim, G., Engel, S. and Macefield, V. (2008), 'Cutaneous vasoconstriction as a measure of incipient autonomic dysreflexia during penile vibratory stimulation in spinal cord injury', Spinal Cord, .
• Henderson, L., Gandevia, S. and Macefield, V. (2008), 'Gender differences in brain activity evoked by muscle and cutaneous pain : a retrospective study of single-trial fMRI data', NeuroImage, vol 39, no 4 , pp 1867 - 1876.
• Henderson, L., Gandevia, S. and Macefield, V. (2007), 'Discrete changes in cortical activation during experimentally induced referred muscle pain - a single fMRI study', Cerebral Cortex, vol 17, no 9 , pp 2050 - 2059.
• Clarke, E., Mcnulty, P., Macefield, V. and Bilston, L. (2007), 'Mechanically evoked sensory and motor responses to dynamic compression of the ulnar nerve', Muscle & Nerve, vol 35, no 3 , pp 303 - 311.
• Bent, L., Bolton, P. and Macefield, V. (2007), 'Vestibular inputs do not influence the fusimotor system in relaxed muscles of the human leg', Experimental Brain Research, vol 180 , pp 97 - 103.
• Lin, C., Macefield, V., Elam, M., Wallin, G., Engel, S. and Kiernan, M. (2007), 'Axonal changes in spinal cord injured patients distal to the site of injury', Brain, vol 130, no 4 , pp 985 - 994.
• Brown, R., Engel, S., Wallin, G., Elam, M. and Macefield, V. (2007), 'Assessing the integrity of sympathetic pathways in spinal cord injury', Autonomic Neuroscience: basic & clinical, vol 134, no 40575 , pp 61 - 68.
• Fallon, J. and Macefield, V. (2007), 'Vibration sensitivity of human muscle spindles and Golgi tendon organs', Muscle & Nerve, vol 36, no 1 , pp 21 - 29.
• Henderson, L., Gandevia, S. and Macefield, V. (2007), 'Somatotopic organization of the processing of muscle and cutaneous pain in the left and right insula cortex: a single-trial fMRI study', Pain, vol 128, no 40575 , pp 20 - 30.
• Macefield, V., Gandevia, S. and Henderson, L. (2006), 'Neural sites involved in the sustained increase in muscle sympathetic nerve activity induced by inspiratory-capacity apnea - a fMRI study', Journal of Applied Physiology, vol 100 , pp 266 - 273.
• Henderson, L., Bandlera, R., Gandevia, S. and Macefield, V. (2006), 'Distinct forebrain activity patterns during deep versus superficial pain', Pain, vol 120, no 3 , pp 286 - 296.
• Bent, L., Bolton, P. and Macefield, V. (2006), 'Modulation of muscle sympathetic bursts by sinusoidal galvanic vestibular stimulation in human subjects', Experimental Brain Research, vol 174, no 4 , pp 701 - 711.
• Fallon, J., Bent, L., McNulty, P. and Macefield, V. (2005), 'Evidence for strong synaptic coupling between single tactile afferents from the sole of the foot and motoneurons supplying leg muscles', Journal of Neurophysiology, vol 94, no 6 , pp 3795 - 3804.
• Klineberg, I., Calford, M., Dreher, B., Henry, P., Macefield, V., Miles, T., Rowe, M., Sessle, B. and Trulsson, M. (2005), 'A consensus statement on osseoperception', Clinical and Experimental Pharmacology and Physiology, vol 32, no 40575 , pp 145 - 146.
• Macefield, V. (2005), 'Physiological characteristics of low-threshold mechanoreceptors in joints, muscle and skin in human subjects', Clinical and Experimental Pharmacology and Physiology, vol 32, no 40575 , pp 135 - 144.
• Macefield, V. and Elam, M. (2004), 'Comparison of the firing patterns of human postganglionic sympathetic neurones and spinal I? motoneurones during brief bursts', Experimental Physiology, vol 89, no 1 , pp 82 - 88.
• Bolton, P., Wardman, D. and Macefield, V. (2004), 'Absence of short-term vestibular modulation of muscle sympathetic outflow, assessed by brief galvanic vestibular stimulation in awake human subjects', Experimental Brain Research, vol 154, no 1 , pp 39 - 43.
• Elam, M. and Macefield, V. (2004), 'Does sympathetic nerve discharge affect the firing of myelinated cutaneous afferents in humans?', Autonomic Neuroscience: Basic and Clinical, vol 111, no 2 , pp 116 - 126.
• Macefield, V., Sverrisdottir, Y. and Wallin, B. (2003), 'Resting discharge of human muscle spindles is not modulated by increases in sympathetic drive', Journal of Physiology, vol 551, no 3 , pp 1005 - 1011.
• Macefield, V. (2003), 'Cardiovascular and respiratory modulation of tactile afferents in the human finger pad', Experimental Physiology, vol 88, no 5 , pp 617 - 625.
• Macefield, V. and Johansson, R. (2003), 'Loads applied tangential to a fingertip during an object restraint task can trigger short-latency as well as long-latency EMG responses in hand muscles', Experimental Brain Research, vol 152, no 2 , pp 143 - 149.
• Macefield, V. and Elam, M. (2003), 'Why do human postganglionic neurones primarily only fire once during a sympathetic burst?', Acta Physiologica Scandinavica, vol 177, no 3 , pp 247 - 253.
• Elam, M., Sverrisdottir, Y., Rundqvist, B., Mckenzie, D., Wallin, B. and Macefield, V. (2003), 'Pathological sympathoexcitation: How is it achieved?', Acta Physiologica Scandinavica, vol 177, no 3 , pp 405 - 411.
• Elam, M., Mckenzie, D. and Macefield, V. (2002), 'Mechanisms of sympatho-excitation: single-unit analysis of muscle vasoconstrictor neurons in awake OSAS subjects', Journal of Applied Physiology, vol 93 , pp 297 - 303.
• McNulty, P., Macefield, V., Taylor, J. and Hallett, M. (2002), 'Cortically evoked neural volleys to the human hand are increased during ischaemic block of the forearm', Journal of Physiology, vol 538, no 1 , pp 279 - 288.
• Macefield, V. and Elam, M. (2002), 'Prolonged surges of baroreflex-resistant muscle sympathetic drive during periodic breathing', Clinical Autonomic Research, vol 12, no 3 , pp 165 - 169.
• McNulty, P. and Macefield, V. (2002), 'Reflexes in the hand: Strong synaptic coupling between single tactile afferents and spinal motoneurones', Advances in Experimental Medicine and Biology, vol 508 , pp 39 - 45.
• Elam, M. and Macefield, V. (2001), 'Multiple firing of single muscle vasoconstrictor neurons during cardiac dysrhythmias in human heart failure', Journal of Applied Physiology, vol 91 , pp 717 - 724.
• Mcnulty, P. and Macefield, V. (2001), 'Modulation of ongoing EMG by different classes of low threshold mechanoreceptors in the human hand', The Journal of Physiology, vol 537 , pp 1021 - 1032.