Doctor Valentina Naumovski

Doctor Valentina Naumovski

Senior Research Fellow,
School of Medicine

Biography

Dr Valentina (Tina) Naumovski (BE (Hons), BSc (Chem.), PhD, GCULT, FHEA) is a Senior Research Fellow in Diabetes at the Macarthur Clinical School, School of Medicine, Western Sydney University, Australia.

Tina is one of very few researchers in the world with a multidisciplinary approach spanning the cultivation, analytical (isolating and identifying bioactive compounds), pharmacological/preclinical (mechanism of action predominantly in diabetes/metabolic syndrome, drug interactions, pharmacokinetics) and clinical (medicinal cannabis for symptom relief and currently, diabetes research) and qualitative research.

Previously, she was the operational lead and provides scientific methodology to a world-leading NSW Government-funded research program on medicinal cannabis clinical trials (Phase I/II/III) in advanced cancer addressing cachexia/anorexia at UNSW. She leads a trans-Tasman group tasked with mapping a program to improve cachexia/anorexia syndrome. Tina has led the nation’s first survey on the experiences of health care professionals dealing with cancer cachexia and is examining an equivalent survey for patients. She has received two highly awarded poster prizes. Before this, she was the operational lead of the Joint Chair in Traditional Chinese Medicine (JCTCM) program at WSU tasked with initiating, progressing and completing the strategic aims of the portfolio. Tina has been invited as a guest lecturer at various forums on cannabis and complementary medicines to further knowledge and education in this field. She won two international best paper award prizes in 2023.

Tina was Senior Lecturer in Pharmacology at the School of Biomedical Sciences-Faculty of Medicine and Health, UNSW, and School of Science at WSU. She is recognised for her teaching by the Higher Education Academy Professional Standards Framework, UK and won the School of Science Staff Excellence Award and was nominated for the Deputy Vice-Chancellor Academic-Teaching Excellence Awards Citations for Outstanding Contributions to Student Learning at Western Sydney University in 2022. 

This information has been contributed by Doctor Naumovski.

Qualifications

  • PhD University of Sydney

Professional Memberships

  • TGA (2023 - 2026)

Organisational Unit (School / Division)

  • School of Medicine

Contact

Email: V.Naumovski@westernsydney.edu.au
Phone:



Mobile:
Location: CampbelltownWestmeadWestmeadHawkesbury

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Publications

Chapters in Books

  • Li, G., Wong, K., Kam, A., Zhou, X., Omar, E., Alqahtani, A., Li, K., Razmovski-Naumovski, V. and Chan, K. (2012), 'Anti-inflammatory nutraceuticals and herbal medicines for the management of metabolic syndrome', Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions, CRC Press 9781439872116.
  • Li, G., Kam, A., Wong, K., Zhou, X., Omar, E., Alqahtani, A., Li, K., Razmovski-Naumovski, V. and Chan, K. (2012), 'Herbal medicines for the management of diabetes ', Diabetes : an Old Disease, a New Insight, Springer 9781461454403.
  • Li, G., Naumovski, V., Kimble, B., Qiao, V., Tongkao-on, W., Lin, B., Mo, S. and Li, K. (2010), 'Quality control methods for herbal medicines', Compendium of Bioactive Natural Products-Quality Control & Standardization, Studium Press 1933699582.
  • Li, G., Naumovski, V., Omar, E., Teoh, A., Song, M., Tongkao-on, W., Nammi, S., Mo, S., Virgona, N. and Li, K. (2010), 'Evaluation of biological activity in quality control of herbal medicines', Comprehensive bioactive natural products : Volume 8 : quality control & standardization, 1933699582.
  • Naumovski, V., Duke, R., Tran, V., Li, G., Tattam, B., Roufogalis, B. and Duke, C. (2008), 'Current methods in the isolation and characterization of saponins from Gynostemma pentaphyllum', Current Trends in Phytochemistry, Research Signpost 9788130802770.

Journal Articles

  • Ellis, J., Petersen, M., Chang, S., Ingham, G., Martin, P., Morgan, N., Vaughan, V., Brown, L., Currow, D. and Razmovski-Naumovski, V. (2023), 'Health care professionals' experiences of dealing with cancer cachexia', International Journal of Clinical Oncology, vol 28, no 4 , pp 592 - 602.
  • Morris, M., Chye, R., Liu, Z., Agar, M. and Razmovski-Naumovski, V. (2023), 'A retrospective medical record review of adults with non-cancer diagnoses prescribed medicinal cannabis', Journal of Clinical Medicine, vol 12, no 4 .
  • Razmovski-Naumovski, V., West, P., Bellemore, F., Byfieldt, N., Bellamy, D., Chye, R., Clark, K., Martin, J., Fazekas, B., Phillips, J. and Agar, M. (2022), 'Defining the trials nurses' role in operationalising a medicinal cannabis clinical trial', Collegian, vol 29, no 3 , pp 370 - 378.
  • Razmovski-Naumovski, V., Kimble, B., Laurenti, D., Nammi, S., Norimoto, H. and Chan, K. (2022), 'Polysaccharide peptide extract from Coriolus versicolor increased Tmax of tamoxifen and maintained biochemical serum parameters, with no change in the metabolism of tamoxifen in the rat', Frontiers in Pharmacology, vol 13 .
  • Zhou, X., Razmovski-Naumovski , V., Mendoza, R., Truong, J. and Chan, K. (2022), 'A comparative study of Salvia miltiorrhiza Radix & Rhizoma raw material and granule products using chromatographic analysis and antioxidant activity', Journal of Traditional Chinese Medical Sciences, vol 9, no 3 , pp 311 - 320.
  • Yousaf, M., Razmovski-Naumovski, V., Zubair, M., Chang, D. and Zhou, X. (2022), 'Synergistic effects of natural product combinations in protecting the endothelium against cardiovascular risk factors', Journal of Evidence-Based Integrative Medicine, vol 27 .
  • Alqahtani, A., Li, K., Razmovski-Naumovski, V., Kam, A., Alam, P. and Li, G. (2021), 'Attenuation of methylglyoxal-induced glycation and cellular dysfunction in wound healing by Centella cordifolia', Saudi Journal of Biological Sciences, vol 28, no 1 , pp 813 - 824.
  • Razmovski-Naumovski, V., Zhou, X., Wong, H., Kam, A., Pearson, J. and Chan, K. (2020), 'Chromatographic, chemometric and antioxidant assessment of the equivalence of granules and herbal materials of Angelicae Sinensis Radix', Medicines, vol 7, no 6 .
  • Zhou, X., Afzal, S., Muench, G., Razmovski-Naumovski, V. and Li, C. (2020), 'Combined effect of 2 nutraceuticals, curcumin and resveratrol on the activation of nuclear factor erythroid 2-related factor 2', Global Advances in Health and Medicine, vol 9 , pp 49 - 49.
  • Alqahtani, A., Hidayathulla, S., Rehman, M., Elgamal, A., Al-Massarani, S., Razmovski-Naumovski, V., Alqahtani, M., El Dib, R. and Alajmi, M. (2020), 'Alpha-amylase and alpha-glucosidase enzyme inhibition and antioxidant potential of 3-oxolupenal and katononic acid isolated from Nuxia oppositifolia', Biomolecules, vol 10, no 1 .
  • Zhou, X., Razmovski-Naumovski, V., Kam, A., Chang, D., Li, C., Chan, K. and Bensoussan, A. (2019), 'Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells', BMC Complementary and Alternative Medicine, vol 19 .
  • Ghelani, H., Razmovski-Naumovski, V., Inampudi, V., Chang, D. and Nammi, S. (2019), 'Atorvastatin improves hepatic lipid metabolism and protects renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats', BioMed Research International, vol 2019 .
  • Ghelani, H., Razmovski-Naumovski, V., Chang, D. and Nammi, S. (2019), 'Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats', BMC Nephrology, vol 20, no 1 .
  • Purpura, M., Lowery, R., Wilson, J., Mannan, H., Muench, G. and Razmovski-Naumovski, V. (2018), 'Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects', European Journal of Nutrition, vol 57, no 3 , pp 929 - 938.
  • Ghelani, H., Naumovski, V., Pragada, R. and Nammi, S. (2018), '(R)-a-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro', BMC Complementary and Alternative Medicine, vol 18 .
  • Ghelani, H., Razmovski-Naumovski, V., Pragada, R. and Nammi, S. (2018), 'Attenuation of glucose-induced myoglobin glycation and the formation of advanced glycation end products (AGEs) by (R)-a-lipoic acid in vitro', Biomolecules, vol 8, no 1 .
  • Wong, K., Li, G., Li, K., Razmovski-Naumovski, V. and Chan, K. (2017), 'Optimisation of Pueraria isoflavonoids by response surface methodology using ultrasonic-assisted extraction', Food Chemistry, vol 231 , pp 231 - 237.
  • Ghelani, H., Razmovski-Naumovski, V. and Nammi, S. (2017), 'Chronic treatment of (R)-a-lipoic acid reduces blood glucose and lipid levels in high-fat diet and low-dose streptozotocin-induced metabolic syndrome and type 2 diabetes in Sprague-Dawley rats', Pharmacology Research & Perspectives, vol 5, no 3 .
  • Alqahtani, A., Cho, J., Wong, K., Li, K., Razmovski-Naumovski, V. and Li, G. (2017), 'Differentiation of three Centella species in Australia as inferred from morphological characteristics, ISSR molecular fingerprinting and phytochemical composition', Frontiers in Plant Science, vol 8 .
  • Zhou, X., Razmovski-Naumovski, V., Kam, A., Chang, D., Li, C., Bensoussan, A. and Chan, K. (2017), 'Synergistic effects of Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination in angiogenesis behavior in EAhy 926 cells', Medicines, vol 4, no 4 .
  • Zhou, X., Seto, S., Chang, D., Kiat, H., Razmovski-Naumovski, V., Chan, K. and Bensoussan, A. (2016), 'Synergistic effects of Chinese herbal medicine : a comprehensive review of methodology and current research', Frontiers in Pharmacology, vol 7 .
  • Zhou, X., Razmovski-Naumovski, V., Chang, D., Li, C., Kam, A., Low, M., Bensoussan, A. and Chan, K. (2016), 'Synergistic effects of Danshen (Salvia Miltiorrhiza Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination in inhibiting inflammation mediators in RAW264.7 cells', BioMed Research International, vol 2016 .
  • Chan, K., Hu, X., Razmovski-Naumovski, V. and Robinson, N. (2015), 'Challenges and opportunities of integrating traditional Chinese medicine into mainstream medicine : a review of the current situation', European Journal of Integrative Medicine, vol 7, no 1 , pp 67 - 75.
  • Wong, K., Razmovski-Naumovski, V., Li, K., Li, G. and Chan, K. (2015), 'Comparing morphological, chemical and anti-diabetic characteristics of Puerariae Lobatae Radix and Puerariae Thomsonii Radix', Journal of Ethnopharmacology, vol 164 , pp 53 - 63.
  • Wong, K., Razmovski-Naumovski, V., Li, K., Li, G. and Chan, K. (2015), 'The quality control of two Pueraria species using Raman spectroscopy coupled with partial least squares analysis', Journal of Raman Spectroscopy, vol 46, no 4 , pp 361 - 368.
  • Zhou, X., Razmovski-Naumovski, V. and Chan, K. (2015), 'A multivariate analysis on the comparison of raw notoginseng (Sanqi) and its granule products by thin-layer chromatography and ultra-performance liquid chromatography', Chinese Medicine, vol 10, no 13 .
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K., Grau, G. and Li, G. (2015), 'Curcumin reduces tumour necrosis factor-enhanced annexin V-positive microparticle release in human vascular endothelial cells', Journal of Pharmacy and Pharmaceutical Sciences, vol 18, no 4 , pp 424 - 433.
  • Alqahtani, A., Tongkao-On, W., Li, K., Razmovski-Naumovski, V., Chan, K. and Li, G. (2015), 'Seasonal variation of triterpenes and phenolic compounds in Australian Centella asiatica (L.) Urb', Phytochemical Analysis, vol 26, no 6 , pp 436 - 443.
  • Kam, A., Razmovski-Naumovski, V., Zhou, X., Truong, J. and Chan, K. (2015), 'Nucleoside transport inhibition by dipyridamole prevents angiogenesis impairment by homocysteine and adenosine', Journal of Pharmacy and Pharmaceutical Sciences, vol 18, no 5 , pp 871 - 881.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2014), 'Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities', International Journal of Cardiology, vol 171, no 2 , pp 231 - 242.
  • Wong, K., Razmovski-Naumovski, V., Li, K., Li, G. and Chan, K. (2014), 'Differentiating Puerariae Lobatae Radix and Puerariae Thomsonii Radix using HPTLC coupled with multivariate classification analyses', Journal of Pharmaceutical and Biomedical Analysis, vol 95 , pp 11 - 19.
  • Razmovski-Naumovski, V., Zhou, X., Grace, R., Wong, H., Lee, S. and Chan, K. (2014), 'Similarity and difference in chemical profile and antioxidant activity between Chinese materia medica decoction pieces and their aqueous granules : Danggui, Danshen and Sanqi', European Journal of Integrative Medicine, vol 6, no 1 , pp 127 - 128.
  • Truong, J., Razmovski-Naumovski, V., Zhou, X., Khoo, C. and Chan, K. (2014), 'A comparative study on the antioxidant activity of Zingiberis Rhizoma raw herb and granule', European Journal of Integrative Medicine, vol 6, no 6 , pp 733 - 733.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2013), 'Variability of the polyphenolic content and antioxidant capacity of methanolic extracts of pomegranate peel', Natural Product Communications, vol 8, no 6 , pp 707 - 710.
  • Wong, K., Razmovski-Naumovski, V., Li, K., Li, G. and Chan, K. (2013), 'Differentiation of Pueraria lobata and Pueraria thomsonii using partial least square discriminant analysis (PLS-DA)', Journal of Pharmaceutical and Biomedical Analysis, vol 84 , pp 5 - 13.
  • Kim, E., Chen, Y., Huang, J., Li, K., Razmovski-Naumovski, V., Poon, J., Chan, K., Roufogalis, B., McLachlan, A., Mo, S., Yang, D., Yao, M., Liu, Z., Liu, J. and Li, G. (2013), 'Evidence-based toxicity evaluation and scheduling of Chinese herbal medicines', Journal of Ethnopharmacology, vol 146, no 1 , pp 40 - 61.
  • Chong, C., Zhou, Z., Razmovski-Naumovski, V., Cui, G., Zhang, L., Sa, F., Hoi, P., Chan, K. and Lee, S. (2013), 'Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish', Neuroscience Letters, vol 543 , pp 121 - 125.
  • Alqahtani, A., Hamid, K., Kam, A., Wong, K., Abdelhak, Z., Razmovski-Naumovski, V., Chan, K., Li, K., Groundwater, P. and Li, G. (2013), 'The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications', Current Medicinal Chemistry, vol 20, no 7 , pp 908 - 931.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Shi, J., Chan, K. and Li, G. (2013), 'A comparative study on the inhibitory effects of different parts and chemical constituents of pomegranate on a-amylase and a-glucosidase', Phytotherapy Research, vol 27, no 11 , pp 1614 - 1620.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Combination of TNF-a, homocysteine and adenosine exacerbated cytotoxicity in human cardiovascular and cerebrovascular endothelial cells', Cellular Physiology and Biochemistry, vol 30, no 3 , pp 805 - 814.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K., Li, Y. and Li, G. (2012), 'The protective effects of natural products on blood-brain barrier breakdown', Current Medicinal Chemistry, vol 19, no 12 , pp 1830 - 1845.
  • Wong, K., Li, G., Li, K., Naumovski, V. and Chan, K. (2011), 'Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, vol 134, no 3 , pp 584 - 604.
  • Wong, K., Li, G., Li, K., Naumovski, V. and Chan, K. (2011), 'Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, vol 134, no 3 , pp 584 - 604.
  • Naumovski, V., Tongkao-on, W., Kimble, B., Qiao, V., Lin, B., Li, K., Roufogalis, B., Yang, D., Yao, M. and Li, G. (2010), 'Multiple chromatographic and chemometric methods for quality standardisation of Chinese herbal medicines', Modernization of Traditional Medicine and Materia Materia-World Science and Technology, vol 12, no 1 , pp 99 - 106.
  • Wong, K., Li, G., Li, K., Naumovski, V. and Chan, K. (2010), 'Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, vol 134, no 3 , pp 584 - 607.
  • Omar, E., Kam, A., Alqahtani, A., Li, K., Naumovski, V., Nammi, S., Chan, K., Roufogalis, B. and Li, G. (2010), 'Herbal medicines and nutraceuticals for diabetic vascular complications : mechanisms of action and bioactive phytochemicals', Current Pharmaceutical Design, vol 16, no 34 , pp 3776 - 3807.
  • Hesse, C., Naumovski, V., Duke, C., Davies, N. and Roufogalis, B. (2007), 'Phytopreventative effects of Gynostemma pentaphyllum against acute indomethacin-induced gastrointestinal and renal toxicity in rats', Phytotherapy Research, vol 21, no 6 , pp 523 - 530.
  • Huang, T., Li, Y., Naumovski, V., Tran, V., Li, G., Duke, C. and Roufogalis, B. (2006), 'Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway', Journal of Biomedical Science, vol 13, no 4 , pp 535 - 548.

Conference Papers

  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Protective effects of pomegranate peel against endothelial cell death caused by homocysteine, adenosine and TNF-alpha', Consortium for Globalization of Chinese Medicine (CGCM), Macau.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Intercontinental Variability in the Polyphenolic Profile and Total Antioxidant Capacity of Pomegranate Peel', 11th Annual Oxford International Conference on the Science of Botanicals (ICBS), Oxford, Mississippi.
  • Naumovski, V., Tongkao-on, W., Kimble, B., Qiao, V., Lin, B., Li, K., Roufogalis, B., Yang, D., Yao, M. and Li, G. (2010), 'Multiple chromatographic and chemometric methods for quality standardisation of Chinese herbal medicines', International Conference & Exposition on Traditional Medicine, Guangdong, China.
  • Lin, B., Qiao, V., Li, K., Naumovski, V. and Li, G. (2010), 'Quantitative determination of carbohydrate in different herbal products with optimised microplate phenol-sulfuric acid method', 5th International Congress on Complementary Medicine Research (ICCMR), Tromso, Norway.
  • Alqahtani, A., Tongkao-on, W., Li, K., Naumovski, V., Kimble, B., Chan, K. and Li, G. (2010), 'Analysis of regional and seasonal variation of triterpene & flavonoid contents in Centella asiatica by high performance liquid chromatography and chemometric analysis', 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong.
  • Tongkao-on, W., Li, K., Naumovski, V., Wang, H., Leach, D., Kimble, B. and Li, G. (2009), 'Determination of triterpene and flavonoid contents in Centella asiatica from 6 Countries by High Performance Liquid Chromatography', Australasian Society of Clinical and Experimental Pharmacologists (ASCEPT), Australia.
  • Tongkao-on, W., Li, K., Naumovski, V., Wang, H., Leach, D., Kimble, B. and Li, G. (2009), 'Determination of triterpene and flavonoid contents in Centella asiatica from 6 Countries by High Performance Liquid Chromatography', Australasian Pharmaceutical Science Association (APSA), Australia.
  • Li, G., Naumovski, V., Yao, M. and Xie, P. (2008), 'Development of a quality control platform for herbal medicines', 3rd International Congress on Complementary Medicine Research (ICCMR), Darling Harbour, Sydney, Australia.
  • Kimble, B., Li, K., Naumovski, V. and Li, G. (2008), 'Phytochemical analysis of the HPLC fingerprints of Hypericum perforatum preparations', College of Health Sciences Research Conference 'From Cell to Society 6', Leura, Sydney, Australia.
  • Tongkao-on, W., Li, K., Naumovski, V. and Li, G. (2008), 'Comparison of Centella asiatica's fingerprinting from 4 different countries by thin layer chromatography and capillary zone electrophoresis', College of Health Sciences Research Conference 'From Cell to Society 6', Leura, Sydney, Australia.
  • Lin, B., Qiao, V., Li, K., Naumovski, V. and Li, G. (2008), 'Quality analysis of Morinda officinalis with modified phenol-sulfuric acid method', College of Health Sciences Research Conference 'From Cell to Society 6', Leura, Sydney, Australia.

Previous Projects

Title: Pharmacological interactions of extracts of Coriolus versicolor, Yunzhi and chemotherapy medications
Funder:
  • University of Western Sydney
  • PuraPharm Australia Pty Ltd
Western Researchers: Kelvin Chan, Valentina Naumovski and Srinivas Nammi
Years: 2013-05-23 - 2015-06-30
ID: P00020998
Title: Synergistic activity of herbal medicines in stroke
Funder:
  • University of Western Sydney
Western Researchers: Kelvin Chan and Valentina Naumovski
Years: 2012-11-15 - 2014-02-03
ID: P00021202

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