Doctor Ritesh Raju

Journal Articles

• Raju, R., Kumar, P., Reddell, P., Cullen, J., Harman, D., Maccarone, A., Kelso, C. and Muench, G. (2024), 'Insignoic acids A - E, unusual a, b-unsaturated keto fatty acids isolated from the exocarp of Australian rainforest tree Endiandra insignis (Lauraceae)', Fitoterapia, vol 173 .
• Raju, R., Mathew, S., Reddell, P. and Muench, G. (2023), 'Ternstroenol F : a new pentacyclic triterpenoid saponin isolated from the Australian rainforest plant Ternstroemia cherryi', Natural Product Research, vol 37, no 14 , pp 2421 - 2426.
• Afzal, S., Raju, R., Or, K. and Muench, G. (2023), 'Identification of Nrf2 activators from the roots of Valeriana officinalis', Planta Medica, vol 89, no 1 , pp 30 - 45.
• Mathew, S., Zhang, K., Zhou, X., Muench, G., Bodkin, F., Li, F. and Raju, R. (2023), 'Myrtinols A-F : new anti-inflammatory peltogynoid flavonoid derivatives from the leaves of Australian Indigenous plant Backhousia myrtifolia', Molecules, vol 28, no 5 .
• Mathew, S., Raju, R., Zhou, X., Bodkin, F., Govindaraghavan, S. and Muench, G. (2023), 'A method and formula for the quantitative analysis of the total bioactivity of natural products', International Journal of Molecular Sciences, vol 24, no 7 .
• Kumar, P., Mathew, S., Gamage, R., Bodkin, F., Doyle, K., Rossetti, I., Wagnon, I., Zhou, X., Raju, R., Gyengesi, E. and Muench, G. (2023), 'From the bush to the brain : preclinical stages of ethnobotanical anti-inflammatory and neuroprotective drug discovery : an Australian example', International Journal of Molecular Sciences, vol 24, no 13 .
• Raju, R., Kumar, P., Eladwy, R., Bhuyan, D., Reddell, P. and Muench, G. (2023), '[In Press] Polysciasoside B and C : new dammarane-type triterpene glycosides from the leaves of Australian rainforest plant Polyscias australiana (F.Muell.) Philipson (Araliaceae)', Natural Product Research, .
• Raju, R., Mathew, S., Singh, A., Reddell, P. and Muench, G. (2022), 'Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala', Natural Product Research, vol 36, no 17 , pp 4364 - 4370.
• Zhou, X., Venigalla, M., Raju, R. and Muench, G. (2022), 'Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease', Journal of Neural Transmission, vol 129, no 5-6 , pp 755 - 771.
• Raju, R., Gunawardena, D., Reddell, P. and Muench, G. (2022), 'Cryptocaryoic acids A - C : new phenyl alkyl acids isolated from the leaves of Australian rainforest plant Cryptocarya mackinnoniana', Fitoterapia, vol 162 .
• Mathew, S., Zhou, X., Muench, G., Bodkin, F., Wallis, M., Li, F. and Raju, R. (2022), 'Tristaenone A : a new anti-inflammatory compound isolated from the Australian Indigenous plant Tristaniopsis laurina', Molecules, vol 27, no 19 .
• Singh, A., Raju, R. and Muench, G. (2021), 'Potential anti-neuroinflammatory compounds from Australian plants : a review', Neurochemistry International, vol 142 .
• Venigalla, M., Roberts, T., Raju, R., Mrad, M., Bodkin, F., Kopp, K., Doyle, K. and Muench, G. (2021), 'Identification of tetragocarbone C and sideroxylin as the most potent anti-inflammatory components of Syncarpia glomulifera', Fitoterapia, vol 150 .
• Raju, R., Cullen, J., Bruce, Z., Reddell, P. and Muench, G. (2021), 'Eupomatenes A - E : neolignans isolated from the leaves of Australian rainforest plant Eupomatia laurina', Fitoterapia, vol 153 .
• Singh, A., Raju, R., Mrad, M., Reddell, P. and Muench, G. (2020), 'The reciprocal EC50 value as a convenient measure of the potency of a compound in bioactivity-guided purification of natural products', Fitoterapia, vol 143 .
• Raju, R., Singh, A., Gunawardena, D., Reddell, P. and Muench, G. (2020), 'Mulgravanols A and B, rare oxidized xanthenes and a new phloroglucinol isolated from the Australian rainforest plant Waterhousea mulgraveana (Myrtaceae)', Fitoterapia, vol 143 .
• Singh, A., Cullen, J., Bruce, Z., Reddell, P., Muench, G. and Raju, R. (2020), 'Ternstroenols A - E : undescribed pentacyclic triterpenoids from the Australian rainforest plant Ternstroemia cherryi', Phytochemistry, vol 176 .
• Raju, R., Singh, A., Bodkin, F. and Muench, G. (2019), 'Costatamins A - C, new 4-phenylcoumarins with anti-inflammatory activity from the Australian woodland tree Angophora costata (Myrtaceae)', Fitoterapia, vol 133 , pp 171 - 174.
• Raju, R., Singh, A., Gunawardena, D., Reddell, P. and Muench, G. (2019), 'Diarylheptanoids with anti-inflammatory activity from the rhizomes of Pleuranthodium racemigerum (Zingiberaceae)', Phytochemistry Letters, vol 30 , pp 10 - 13.
• Dhananjayan, K., Irrgang, F., Raju, R., Harman, D., Moran, C., Srikanth, V. and Muench, G. (2019), 'Determination of glyoxal and methylglyoxal in serum by UHPLC coupled with fluoresecence detection', Analytical Biochemistry, vol 573 , pp 51 - 66.
• Gunawardena, D., Raju, R. and Muench, G. (2019), 'Hydrogen peroxide mediates pro-inflammatory cell-to-cell signaling : a new therapeutic target for inflammation?', Neural Regeneration Research, vol 14, no 8 , pp 1430 - 1437.
• Singh, A., Muench, G., Reddell, P., Radzieta, M., Jensen, S., Jensen, S. and Raju, R. (2018), 'A new anti-inflammatory phenolic monosaccharide from the Australian native rainforest plant Elaeocarpus eumundi', Natural Product Communications, vol 13, no 6 , pp 731 - 733.
• Raju, R., Singh, A., Reddell, P. and Muench, G. (2018), 'Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)', Phytochemistry Letters, vol 27 , pp 197 - 202.
• Akhtar, M., Muench, G., Bodkin, F. and Raju, R. (2018), 'A new anti-inflammatory chromone from the leaves of Eucalyptus viminalis', Natural Product Communications, vol 13, no 10 , pp 1297 - 1301.
• Kjaerulff, L., Raju, R., Panter, F., Scheid, U., Garcia, R., Herrmann, J. and Muller, R. (2017), 'Pyxipyrrolones : novel cytotoxic myxobacterial metabolites : structure elucidation and biosynthesis proposal', Angewandte Chemie (International Edition), vol 56, no 32 , pp 9614 - 9618.
• Shang, Z., Raju, R., Salim, A., Khalil, Z. and Capon, R. (2017), 'Cytochalasins from an Australian marine sediment-derived Phomopsis sp. (CMB-M0042F) : acid-mediated intramolecular cycloadditions enhance chemical diversity', The Journal of Organic Chemistry, vol 82, no 18 , pp 9704 - 9709.
• Tu, Q., Herrmann, J., Hu, S., Raju, R., Bian, X., Zhang, Y. and Muller, R. (2016), 'Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering', Scientific Reports, vol 6 .
• Raju, R., Gunawardena, D., Akhtar, M., Low, M., Reddell, P. and Muench, G. (2016), 'Anti-inflammatory chemical profiling of the Australian rainforest tree Alphitonia petriei (Rhamnaceae)', Molecules, vol 21, no 11 .
• Akhtar, M., Raju, R., Beattie, K., Bodkin, F. and Muench, G. (2016), 'Medicinal plants of the Australian Aboriginal Dharawal people exhibiting anti-inflammatory activity', Evidence-Based Complementary and Alternative Medicine, vol 2016 .
• Gunawardena, D., Karunaweera, N., Lee, S., van der Kooy, F., Harman, D., Raju, R., Bennett, L., Gyengesi, E., Sucher, N. and Muench, G. (2015), 'Anti-inflammatory activity of cinnamon (C. zeylanicum and C. cassia) extracts - identification of e-cinnamaldehyde and o-methoxy cinnamaldehyde as the most potent bioactive compounds', Food and Function, vol 6, no 3 , pp 910 - 919.
• Raju, R., Mohr, K., Bernecker, S., Herrmann, J. and Muller, R. (2015), 'Cystodienoic acid : a new diterpene isolated from the myxobacterium Cystobacter sp.', Journal of Antibiotics, vol 68, no 7 , pp 473 - 475.
• Karunaweera, N., Raju, R., Gyengesi, E. and Muench, G. (2015), 'Plant polyphenols as inhibitors of NF-KB induced cytokine production : a potential anti-inflammatory treatment for Alzheimer's disease?', Frontiers in Molecular Neuroscience, vol 8 .
• Khalil, Z., Raju, R., Piggott, A., Salim, A., Blumenthal, A. and Capon, R. (2015), 'Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian marine-derived Streptomyces sp.', Journal of Natural Products, vol 78, no 4 , pp 949 - 952.
• Raju, R., Gromyko, O., Fedorenko, V., Luzketskyy, A. and Muller, R. (2015), 'Albaflavenol B, a new sesquiterpene isolated from the terrestrial actinomycete, Streptomyces sp.', The Journal of Antibiotics, vol 68, no 4 , pp 286 - 288.
• Raju, R., Khalil, Z., Piggott, A., Blumenthal, A., Gardiner, D., Skinner-Adams, T. and Capon, R. (2014), 'Mollemycin A : an antimalarial and antibacterial glycohexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)', Organic Letters, vol 16, no 6 , pp 1716 - 1719.
• Raju, R., Gromyko, O., Andriy, B., Fedorenko, V., Luzhetskyy, A. and Muller, R. (2014), 'Oleamycins A and B : new antibacterial cyclic hexadepsipeptides isolated from a terrestrial Streptomyces sp.', Journal of Antibiotics, vol 67 , pp 339 - 343.
• Raju, R., Garcia, R. and Muller, R. (2014), 'Angiolactone, a new Butyrolactone isolated from the terrestrial myxobacterium, Angiococcus sp.', Journal of Antibiotics, vol 67 , pp 725 - 726.
• Baumann, S., Herrmann, J., Raju, R., Steinmetz, H., Mohr, K., Huttel, S., Harmrolfs, K., Stadler, M. and Muller, R. (2014), 'Cystobactamids : myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity', Angewandte Chemie (International Edition), vol 53, no 52 , pp 14605 - 14609.
• Khalil, Z., Huang, X., Raju, R., Piggott, A. and Capon, R. (2014), 'Shornephine A : structure, chemical stability, and P-glycoprotein inhibitory properties of a rare diketomorpholine from an Australian marine-derived aspergillus sp.', The Journal of Organic Chemistry, vol 79, no 18 , pp 8700 - 8705.
• Raju, R., Gromyko, O., Fedorenko, V., Herrmann, J., Luzhetskyy, A. and Muller, R. (2013), 'Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.', Tetrahedron Letters, vol 54, no 8 , pp 900 - 902.
• Raju, R., Gromyko, O., Fedorenko, V., Luzhetskyy, A. and Muller, R. (2013), 'Oleaceran : a novel spiro[isobenzofuran-1,2'-naptho[1,8-bc]furan] isolated from a terrestrial Streptomyces sp.', Organic Letters, vol 15, no 14 , pp 3487 - 3489.
• Raju, R., Gromyko, O., Fedorenko, V., Luzhetskyy, A. and Muller, R. (2013), 'Lorneic acids C and D, new trialkyl-substituted aromatic acids isolated from a terrestrial Streptomyces sp.', The Journal of Antibiotics, vol 66, no 6 , pp 347 - 349.
• Raju, R., Piggott, A., Quezada, M. and Capon, R. (2013), 'Nocardiopsins C and D and nocardiopyrone A : new polyketides from an Australian marine-derived Nocardiopsis sp.', Tetrahedron, vol 69, no 2 , pp 692 - 698.
• Raju, R., Gromyko, O., Fedorenko, V., Luzhetskyy, A. and Muller, R. (2012), 'Pimprinols A-C, from the terrestrial actinomycete, Streptomyces sp.', Tetrahedron Letters, vol 53, no 24 , pp 3009 - 3011.
• Raju, R., Gromyko, O., Fedorenko, V., Luzhetskyy, A., Plaza, A. and Muller, R. (2012), 'Juniperolide A : a new polyketide isolated from a terrestrial actinomycete, Streptomyces sp.', Organic Letters, vol 14, no 23 , pp 5860 - 5863.
• Raju, R., Gromyko, O., Fedorenko, V., Luzhetskyy, A. and Muller, R. (2012), 'Leopolic acid A, isolated from a terrestrial actinomycete, Streptomyces sp.', Tetrahedron Letters, vol 53, no 46 , pp 6300 - 6301.
• Raju, R., Kawabata, K., Nishijima, M. and Aalbersberg, W. (2012), 'Kailuin F, a new cyclic acyldepsipeptide from a marine-derived bacterium', Tetrahedron Letters, vol 53, no 51 , pp 6905 - 6907.
• Raju, R., Piggott, A., Khalil, Z., Bernhardt, P. and Capon, R. (2012), 'Heronamycin A : a new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.', Tetrahedron Letters, vol 53, no 9 , pp 1063 - 1065.
• Raju, R., Piggott, A., Huang, X. and Capon, R. (2011), 'Nocardioazines : a novel bridged diketopiperazine scaffold from a marine-derived bacterium inhibits p-glycoprotein', Organic Letters, vol 13, no 10 , pp 2770 - 2773.
• Sun, P., Maloney, K., Nam, S., Haste, N., Raju, R., Aalbersberg, W., Jensen, P., Nizet, V., Hensler, M. and Fenical, W. (2011), 'Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp.', Bioorganic and Medicinal Chemistry, vol 19, no 22 , pp 6557 - 6562.
• Raju, R., Piggott, A., Conte, M., Tnimov, Z., Alexandrov, K. and Capon, R. (2010), 'Nocardiopsins : new FKBP12-binding macrolide polyketides from an Australian marine-derived actinomycete, Nocardiopsis sp.', Chemistry: A European Journal, vol 16, no 10 , pp 3194 - 3200.
• Raju, R., Piggott, A., Conte, M. and Capon, R. (2010), 'Heronamides A-C, new polyketide macrolactams from an Australian marine-derived Streptomyces sp. A biosynthetic case for synchronized tandem electrocyclization', Organic and Biomolecular Chemistry, vol 8, no 20 , pp 4682 - 4689.
• Raju, R., Piggott, A., Barrientos Diaz, L., Khalil, Z. and Capon, R. (2010), 'Heronapyrroles A-C : farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces sp.', Organic Letters, vol 12, no 22 , pp 5158 - 5161.
• Raju, R., Piggott, A., Conte, M., Aalbersberg, W., Feussner, K. and Capon, R. (2009), 'Naseseazines A and B : a new dimeric diketopiperazine framework from a marine-derived actinomycete, Streptomyces sp.', Organic Letters, vol 11, no 17 , pp 3862 - 3865.