Professor Eileen McLaughlin

Professor Eileen McLaughlin

Dean - School of Science,
Dean's Unit, School of Science

Dean - School of Science,
Dean's Unit, School of Science

Biography

Qualifications

  • PhD Bristol University (UK)

Organisational Unit (School / Division)

  • Dean's Unit, School of Science
  • Dean's Unit, School of Science

Contact

Email: E.McLaughlin@westernsydney.edu.au
Phone: (02) 4570 1114
Mobile:
Location: M15.1.10
Hawkesbury

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Publications

Chapters in Books

  • Holt, J., Stanger, S., Nixon, B. and McLaughlin, E. (2016), 'Non-coding RNA in spermatogenesis and epididymal maturation', Non-coding RNA and the Reproductive System, Springer 9789401774154.
  • Sutherland, J., McLaughlin, E., Hime, G. and Siddall, N. (2013), 'The Musashi family of RNA binding proteins : master regulators of multiple stem cell populations', Advances in Experimental Medicine and Biology. Volume 786, Transcriptional and Translational Regulation of Stem Cells, Springer 9789400766204.
  • Sobinoff, A., Bernstein, I. and McLaughlin, E. (2012), 'All your eggs in one basket : mechanisms of xenobiotic induced female reproductive senescence', Senescence, IntechOpen 9789535104444.
  • McLaughlin, E. and Sobinoff, A. (2010), 'Contraception targets in mammalian ovarian development', Fertility Control, Springer 9783642020612.

Journal Articles

  • Frost, E., Ford, E., Taylor, G., Boeing, S., Beckett, E., Roman, S., Lovell-Badge, R., McLaughlin, E. and Sutherland, J. (2021), '[In Press] Two alternative methods for the retrieval of somatic cell populations from the mouse ovary', Molecular Human Reproduction, .
  • Ford, E., Beckett, E., Roman, S., McLaughlin, E. and Sutherland, J. (2020), 'Advances in human primordial follicle activation and premature ovarian insufficiency', Reproduction, vol 159, no 1 , pp 15 - 29.
  • Mihalas, B., Redgrove, K., Bernstein, I., Robertson, M., McCluskey, A., Nixon, B., Holt, J., McLaughlin, E. and Sutherland, J. (2020), 'Dynamin 2-dependent endocytosis is essential for mouse oocyte development and fertility', The FASEB Journal, vol 34, no 4 , pp 5162 - 5177.
  • Ford, E., Roman, S., McLaughlin, E., Beckett, E. and Sutherland, J. (2020), 'The association between reproductive health smartphone applications and fertility knowledge of Australian women', BMC Women's Health, vol 20, no 1 .
  • Bryan, E., Redgrove, K., Mooney, A., Mihalas, B., Sutherland, J., Carey, A., Armitage, C., Trim, L., Kollipara, A., Mulvey, P., Palframan, E., Trollope, G., Bogoevski, K., McLachlan, R., McLaughlin, E. and Beagley, K. (2020), 'Chronic testicular Chlamydia muridarum infection impairs mouse fertility and offspring development', Biology of Reproduction, vol 102, no 4 , pp 888 - 901.
  • Frost, E., Ford, E., Peters, A., Reed, N., McLaughlin, E., Baker, M., Lovell-Badge, R. and Sutherland, J. (2020), 'Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line', Reproduction, Fertility and Development, vol 32, no 12 , pp 1027 - 1039.
  • Bryan, E., McLachlan, R., Rombauts, L., Katz, D., Yazdani, A., Bogoevski, K., Chang, C., Giles, M., Carey, A., Armitage, C., Trim, L., McLaughlin, E. and Beagley, K. (2019), 'Detection of chlamydia infection within human testicular biopsies', Human Reproduction, vol 34, no 10 , pp 1891 - 1898.
  • Bryan, E., Kollipara, A., Trim, L., Armitage, C., Carey, A., Mihalas, B., Redgrove, K., McLaughlin, E. and Beagley, K. (2019), 'Hematogenous dissemination of Chlamydia muridarum from the urethra in macrophages causes testicular infection and sperm DNA damage', Biology of Reproduction, vol 101, no 4 , pp 748 - 759.
  • Mihalas, B., Camlin, N., Xavier, M., Peters, A., Holt, J., Sutherland, J., McLaughlin, E., Eamens, A. and Nixon, B. (2019), 'The small non-coding RNA profile of mouse oocytes is modified during aging', Aging, vol 11, no 10 , pp 2968 - 2997.
  • Bromfield, E., Walters, J., Cafe, S., Bernstein, I., Stanger, S., Anderson, A., Aitken, R., McLaughlin, E., Dun, M., Gadella, B. and Nixon, B. (2019), 'Differential cell death decisions in the testis : evidence for an exclusive window of ferroptosis in round spermatids', Molecular Human Reproduction, vol 25, no 5 , pp 241 - 256.
  • Zhou, W., Stanger, S., Anderson, A., Bernstein, I., De Iuliis, G., McCluskey, A., McLaughlin, E., Dun, M. and Nixon, B. (2019), 'Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions', BMC Biology, vol 17, no 1 .
  • Mihalas, B., Bromfield, E., Sutherland, J., De Iuliis, G., McLaughlin, E., Aitken, R. and Nixon, B. (2018), 'Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity', Journal of Biological Chemistry, vol 293, no 49 , pp 18944 - 18964.
  • Hall, S., Upton, R., McLaughlin, E. and Sutherland, J. (2018), 'Phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and Janus kinase/signal transducer and activator of transcription (JAK/STAT) follicular signalling is conserved in the mare ovary', Reproduction, Fertility and Development, vol 30, no 4 , pp 624 - 633.
  • Saeidi, S., Shapouri, F., De Iongh, R., Casagranda, F., Sutherland, J., Western, P., McLaughlin, E., Familari, M. and Hime, G. (2018), 'Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis', PLoS One, vol 13, no 1 .
  • Walters, J., De Iuliis, G., Dun, M., Aitken, R., McLaughlin, E., Nixon, B. and Bromfield, E. (2018), 'Pharmacological inhibition of arachidonate 15-lipoxygenase protects human spermatozoa against oxidative stress', Biology of Reproduction, vol 98, no 6 , pp 784 - 794.
  • Sutherland, J., Frost, E., Ford, E., Peters, A., Reed, N., Seldon, A., Mihalas, B., Russel, D., Dunning, K. and McLaughlin, E. (2018), 'Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary', Molecular Human Reproduction, vol 24, no 11 , pp 533 - 542.
  • Micati, D., Hime, G., McLaughlin, E., Abud, H. and Loveland, K. (2018), 'Differential expression profiles of conserved Snail transcription factors in the mouse testis', Andrology, vol 6, no 2 , pp 362 - 373.
  • Sutherland, J., Sobinoff, A., Fraser, B., Redgrove, K., Siddall, N., Koopman, P., Hime, G. and McLaughlin, E. (2018), 'RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis', Journal of Cellular Physiology, vol 233, no 4 , pp 3262 - 3273.
  • Trinh, T., McLaughlin, E., Gordon, C., Bernstein, I., Pye, V., Redgrove, K. and McCluskey, A. (2017), 'Small molecule Hedgehog pathway antagonists', Organic and Biomolecular Chemistry, vol 15, no 14 , pp 3046 - 3059.
  • Camlin, N., McLaughlin, E. and Holt, J. (2017), 'Motoring through : the role of kinesin superfamily proteins in female meiosis', Human Reproduction Update, vol 23, no 4 , pp 409 - 420.
  • Camlin, N., McLaughlin, E. and Holt, J. (2017), 'The use of C57Bl/6 ? CBA F1 hybrid cross as a model for human age-related oocyte aneuploidy', Molecular Reproduction and Development, vol 84, no 1 , pp 6 - 7.
  • Camlin, N., McLaughlin, E. and Holt, J. (2017), 'Kif4 is essential for mouse oocyte meiosis', PLoS One, vol 12, no 1 .
  • Bromfield, E., Mihalas, B., Dun, M., John, A., McLaughlin, E., Walters, J. and Nixon, B. (2017), 'Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells', Biology of Reproduction, vol 96, no 3 , pp 598 - 609.
  • Zhou, W., De Iuliis, G., Turner, A., Reid, A., Anderson, A., McCluskey, A., McLaughlin, E. and Nixon, B. (2017), 'Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis', Biology of Reproduction, vol 96, no 1 , pp 159 - 173.
  • Bromfield, E., Aitken, R., McLaughlin, E. and Nixon, B. (2017), 'Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse', Molecular Human Reproduction, vol 23, no 2 , pp 91 - 105.
  • Mihalas, B., Redgrove, K., McLaughlin, E. and Nixon, B. (2017), 'Molecular mechanisms responsible for increased vulnerability of the ageing oocyte to oxidative damage', Oxidative Medicine and Cellular Longevity, vol 2017 .
  • Camlin, N., Jarnicki, A., Vanders, R., Walters, K., Hansbro, P., McLaughlin, E. and Holt, J. (2017), 'Grandmaternal smoke exposure reduces female fertility in a murine model, with great-grandmaternal smoke exposure unlikely to have an effect', Human Reproduction, vol 32, no 6 , pp 1270 - 1281.
  • Siddall, N., Sutherland, J., McLaughlin, E. and Hime, G. (2017), 'Drosophila Musashi is required in the ovary to regulate follicle stem cell behaviour and maintain niche homeostasis', Mechanisms of Development, vol 145, no Suppl. , pp 171 - 171.
  • Mihalas, B., De Iuliis, G., Redgrove, K., McLaughlin, E. and Nixon, B. (2017), 'The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte', Scientific Reports, vol 7, no 1 .
  • Zhou, W., Anderson, A., Turner, A., De Iuliis, G., McCluskey, A., McLaughlin, E. and Nixon, B. (2017), 'Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis', Molecular Human Reproduction, vol 23, no 10 , pp 657 - 673.
  • Fuller, E., Sominsky, L., Sutherland, J., Redgrove, K., Harms, L., McLaughlin, E. and Hodgson, D. (2017), 'Neonatal immune activation depletes the ovarian follicle reserve and alters ovarian acute inflammatory mediators in neonatal rats', Biology of Reproduction, vol 97, no 5 , pp 719 - 730.
  • Sominsky, L., Hodgson, D., McLaughlin, E., Smith, R., Wall, H. and Spencer, S. (2017), 'Linking stress and infertility : a novel role for ghrelin', Endocrine Reviews, vol 38, no 5 , pp 432 - 467.
  • Hutcheon, K., McLaughlin, E., Stanger, S., Bernstein, I., Dun, M., Eamens, A. and Nixon, B. (2017), 'Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa', RNA Biology, vol 14, no 12 , pp 1776 - 1790.
  • Trinh, T., McLaughlin, E., Abdel-Hamid, M., Gordon, C., Bernstein, I., Pye, V., Cossar, P., Sakoff, J. and McCluskey, A. (2016), 'Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors', Organic and Biomolecular Chemistry, vol 14, no 26 , pp 6304 - 6315.
  • Redgrove, K., Bernstein, I., Pye, V., Mihalas, B., Sutherland, J., Nixon, B., McCluskey, A., Robinson, P., Holt, J. and McLaughlin, E. (2016), 'Dynamin 2 is essential for mammalian spermatogenesis', Scientific Reports, vol 6 .
  • Reilly, J., McLaughlin, E., Stanger, S., Anderson, A., Hutcheon, K., Church, K., Mihalas, B., Tyagi, S., Holt, J., Eamens, A. and Nixon, B. (2016), 'Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome', Scientific Reports, vol 6 .
  • Stanger, S., Law, E., Jamsai, D., O'Bryan, M., Nixon, B., McLaughlin, E., Aitken, R. and Roman, S. (2016), 'A novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitation', The FASEB Journal, vol 30, no 8 , pp 2777 - 2791.
  • Kumar, M., Camlin, N., Holt, J., Teixeira, J., McLaughlin, E. and Tanwar, P. (2016), 'Germ cell specific overactivation of WNT/?catenin signalling has no effect on folliculogenesis but causes fertility defects due to abnormal foetal development', Scientific Reports, vol 6 .
  • Bromfield, E., McLaughlin, E., Aitken, R. and Nixon, B. (2016), 'Heat shock protein member A2 forms a stable complex with angiotensin converting enzyme and protein disulfide isomerase A6 in human spermatozoa', Molecular Human Reproduction, vol 22, no 2 , pp 93 - 109.
  • Shapouri, F., Saeidi, S., Iongh, R., Casagranda, F., Western, P., McLaughlin, E., Sutherland, J., Hime, G. and Familari, M. (2016), 'Tob1 is expressed in developing and adult gonads and is associated with the P-body marker, Dcp2', Cell and Tissue Research, vol 364, no 2 , pp 443 - 451.
  • Camlin, N., Sobinoff, A., Sutherland, J., Beckett, E., Jarnicki, A., Vanders, R., Hansbro, P., McLaughlin, E. and Holt, J. (2016), 'Maternal smoke exposure impairs the long-term fertility of female offspring in a murine model', Biology of Reproduction, vol 94, no 2 , pp 1 - 12.
  • Sutherland, J., Sobinoff, A., Gunter, K., Fraser, B., Pye, V., Bernstein, I., Boon, E., Siddall, N., Andres, L., Hime, G., Holt, J., Graf, T. and McLaughlin, E. (2015), 'Knockout of RNA binding protein MSI2 impairs follicle development in the mouse ovary : characterization of MSI1 and MSI2 during folliculogenesis', Biomolecules, vol 5, no 3 , pp 1228 - 1244.
  • Sobinoff, A., Dando, S., Redgrove, K., Sutherland, J., Stanger, S., Armitage, C., Timms, P., McLaughlin, E. and Beagley, K. (2015), 'Chlamydia muridarum infection-induced destruction of male germ cells and sertoli cells is partially prevented by Chlamydia major outer membrane protein-specific immune CD4 cells', Biology of Reproduction, vol 92, no 1 , pp 1 - 13.
  • Nixon, B., Stanger, S., Mihalas, B., Reilly, J., Anderson, A., Tyagi, S., Holt, J. and McLaughlin, E. (2015), 'The MicroRNA signature of mouse spermatozoa is substantially modified during epididymal maturation', Biology of Reproduction, vol 93, no 4 , pp 1 - 20.
  • Mihalas, B., Western, P., Loveland, K., McLaughlin, E. and Holt, J. (2015), 'Changing expression and subcellular distribution of karyopherins during murine oogenesis', Reproduction, vol 150, no 6 , pp 485 - 496.
  • Nixon, B., Stanger, S., Mihalas, B., Reilly, J., Anderson, A., Dun, M., Tyagi, S., Holt, J. and McLaughlin, E. (2015), 'Next generation sequencing analysis reveals segmental patterns of microRNA expression in mouse epididymal epithelial cells', PLoS One, vol 10, no 8 .
  • Sutherland, J., Siddall, N., Hime, G. and McLaughlin, E. (2015), 'RNA binding proteins in spermatogenesis : an in depth focus on the Musashi family', Asian Journal of Andrology, vol 17, no 4 , pp 529 - 536.
  • Anderson, A., Stanger, S., Mihalas, B., Tyagi, S., Holt, J., McLaughlin, E. and Nixon, B. (2015), 'Assessment of microRNA expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing', Genomics Data, vol 6 , pp 208 - 211.
  • Nixon, B., Bromfield, E., Dun, M., Redgrove, K., McLaughlin, E. and Aitken, R. (2015), 'The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition', Asian Journal of Andrology, vol 17, no 4 , pp 568 - 573.
  • Bromfield, E., Aitken, R., Anderson, A., McLaughlin, E. and Nixon, B. (2015), 'The impact of oxidative stress on chaperone-mediated human sperm-egg interaction', Human Reproduction, vol 30, no 11 , pp 2597 - 2613.
  • Reid, A., Anderson, A., Roman, S., McLaughlin, E., McCluskey, A., Robinson, P., Aitken, R. and Nixon, B. (2015), 'Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation', FASEB Journal, vol 29, no 7 , pp 2872 - 2882.
  • Sutherland, J., Sobinoff, A., Fraser, B., Redgrove, K., Davidson, T., Siddall, N., Koopman, P., Hime, G. and McLaughlin, E. (2015), 'RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus', FASEB Journal, vol 29, no 7 , pp 2759 - 2768.
  • Trinh, T., McLaughlin, E., Gordon, C. and McCluskey, A. (2014), 'Hedgehog signalling pathway inhibitors as cancer suppressing agents', MedChemComm, vol 5, no 2 , pp 117 - 133.
  • Robker, R., Watson, L., Robertson, S., Dunning, K., McLaughlin, E. and Russell, D. (2014), 'Identification of sites of STAT3 action in the female reproductive tract through conditional gene deletion', PLoS One, vol 9, no 7 .
  • Camlin, N., McLaughlin, E. and Holt, J. (2014), 'Through the smoke : use of in vivo and in vitro cigarette smoking models to elucidate its effect on female fertility', Toxicology and Applied Pharmacology, vol 281, no 3 , pp 266 - 275.
  • Holt, J., Pye, V., Boon, E., Stewart, J., Garcia-Higuera, I., Moreno, S., Rodriguez, R., Jones, K. and McLaughlin, E. (2014), 'The APC/C activator FZR1 is essential for meiotic prophase I in mice', Development (Cambridge), vol 141, no 6 , pp 1354 - 1365.
  • Sahin, Z., Szczepny, A., McLaughlin, E., Meistrich, M., Zhou, W., Ustunel, I. and Loveland, K. (2014), 'Dynamic Hedgehog signalling pathway activity in germline stem cells', Andrology, vol 2, no 2 , pp 267 - 274.
  • Sutherland, J., Fraser, B., Sobinoff, A., Pye, V., Davidson, T., Siddall, N., Koopman, P., Hime, G. and McLaughlin, E. (2014), 'Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis : analysis of the deleterious effects of dysregulated expression', Biology of Reproduction, vol 90, no 5 , pp 1 - 12.
  • Yun, Y., Holt, J., Lane, S., McLaughlin, E., Merriman, J. and Jones, K. (2014), 'Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice', Cell Cycle, vol 13, no 12 , pp 1938 - 1947.
  • Redgrove, K. and McLaughlin, E. (2014), 'The role of the immune response in Chlamydia trachomatis infection of the male genital tract : a double-edged sword', Frontiers in Immunology, vol 5 .
  • Sobinoff, A., Sutherland, J., Beckett, E., Stanger, S., Johnson, R., Jarnicki, A., McCluskey, A., St. John, J., Hansbro, P. and McLaughlin, E. (2014), 'Damaging legacy : maternal cigarette smoking has long-term consequences for male offspring fertility', Human Reproduction, vol 29, no 12 , pp 2719 - 2735.
  • McIver, S., Loveland, K., Roman, S., Nixon, B., Kitazawa, R. and McLaughlin, E. (2013), 'The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis', Andrology (Hoboken), vol 1, no 3 , pp 517 - 529.
  • Davies, R., Wagstaff, K., McLaughlin, E., Loveland, K. and Jans, D. (2013), 'The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins', Biochimica et Biophysica Acta. Molecular Cell Research, vol 1833, no 12 , pp 3436 - 3444.
  • Sominsky, L., Sobinoff, A., Jobling, M., Pye, V., McLaughlin, E. and Hodgson, D. (2013), 'Immune regulation of ovarian development : programming by neonatal immune challenge', Frontiers in Neuroscience, vol 7 .
  • McIver, S., Roman, S., Nixon, B., Loveland, K. and McLaughlin, E. (2013), 'The rise of testicular germ cell tumours : the search for causes, risk factors and novel therapeutic targets', F1000Research, vol 2 .
  • Merriman, J., Lane, S., Holt, J., Jennings, P., Garcia-Higuera, I., Moreno, S., McLaughlin, E. and Jones, K. (2013), 'Reduced chromosome cohesion measured by interkinetochore distance is associated with aneuploidy even in oocytes from young mice', Biology of Reproduction, vol 88, no 2 .
  • Redgrove, K., Anderson, A., McLaughlin, E., O'Bryan, M., Aitken, R. and Nixon, B. (2013), 'Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition', Molecular Human Reproduction, vol 19, no 3 , pp 120 - 135.
  • O'Bryan, M., Clark, B., McLaughlin, E., D'Sylva, R., O'Donnell, L., Wilce, J., Sutherland, J., O'Connor, A., Whittle, B., Goodnow, C., Ormandy, C. and Jamsai, D. (2013), 'RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility', PLoS Genetics, vol 9, no 7 .
  • Sobinoff, A., Sutherland, J. and McLaughlin, E. (2013), 'Intracellular signalling during female gametogenesis', Molecular Human Reproduction, vol 19, no 5 , pp 265 - 278.
  • Sobinoff, A., Beckett, E., Jarnicki, A., Sutherland, J., McCluskey, A., Hansbro, P. and McLaughlin, E. (2013), 'Scrambled and fried : cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress', Toxicology and Applied Pharmacology, vol 271, no 2 , pp 156 - 167.
  • Loveland, K. and McLaughlin, E. (2013), 'Hidden gems in the niche : a new approach to the study of spermatogonial stem cells', Asian Journal of Andrology, vol 15, no 2 , pp 214 - 215.
  • Sominsky, L., Meehan, C., Walker, A., Bobrovskaya, L., McLaughlin, E. and Hodgson, D. (2012), 'Neonatal immune challenge alters reproductive development in the female rat', Hormones and Behavior, vol 62, no 3 , pp 345 - 355.
  • Sobinoff, A., Nixon, B., Roman, S. and McLaughlin, E. (2012), 'Staying alive : PI3k pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity', Toxicological Sciences, vol 128, no 1 , pp 258 - 271.
  • Merriman, J., Jennings, P., McLaughlin, E. and Jones, K. (2012), 'Effect of aging on superovulation efficiency, aneuploidy rates, and sister chromatid cohesion in mice aged up to 15 months', Biology of Reproduction, vol 86, no 2 .
  • Dun, M., Anderson, A., Bromfield, E., Asquith, K., Emmett, B., McLaughlin, E., Aitken, R. and Nixon, B. (2012), 'Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10)', International Journal of Andrology, vol 35, no 4 , pp 572 - 589.
  • Siddall, N., Kalcina, M., Johanson, T., Monk, A., Casagranda, F., Been, R., McLaughlin, E. and Hime, G. (2012), 'Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour', PLoS One, vol 7, no 11 .
  • Sobinoff, A., Pye, V., Nixon, B., Roman, S. and McLaughlin, E. (2012), 'Jumping the gun : smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress', Toxicology and Applied Pharmacology, vol 260, no 1 , pp 70 - 80.
  • Sutherland, J., Keightley, R., Nixon, B., Roman, S., Robker, R., Russell, D. and McLaughlin, E. (2012), 'Suppressor of cytokine signaling 4 (SOCS4) : moderator of ovarian primordial follicle activation', Journal of Cellular Physiology, vol 227, no 3 , pp 1188 - 1198.
  • McIver, S., Stanger, S., Santarelli, D., Roman, S., Nixon, B. and McLaughlin, E. (2012), 'A unique combination of male germ cell miRNAs coordinates gonocyte differentiation', PLoS One, vol 7, no 4 .
  • McIver, S., Roman, S., Nixon, B. and McLaughlin, E. (2012), 'miRNA and mammalian male germ cells', Human Reproduction Update, vol 18, no 1 , pp 44 - 59.
  • McLaughlin, E. and Hime, G. (2011), 'Spermatids do it differently! : Paip2a-the essential regulator of spermiogenesis?', Asian Journal of Andrology, vol 13, no 1 , pp 122 - 124.
  • Redgrove, K., Anderson, A., Dun, M., McLaughlin, E., O'Bryan, M., Aitken, R. and Nixon, B. (2011), 'Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae', Developmental Biology, vol 356, no 2 , pp 460 - 474.
  • Nixon, B., Mitchell, L., Anderson, A., McLaughlin, E., O'Bryan, M. and Aitken, R. (2011), 'Proteomic and functional analysis of human sperm detergent resistant membranes', Journal of Cellular Physiology, vol 226, no 10 , pp 2651 - 2665.
  • Walker, A., Hiles, S., Sominsky, L., McLaughlin, E. and Hodgson, D. (2011), 'Neonatal lipopolysaccharide exposure impairs sexual development and reproductive success in the Wistar rat', Brain, Behavior, and Immunity, vol 25, no 4 , pp 674 - 684.
  • McLaughlin, E. and Aitken, R. (2011), 'Is there a role for immunocontraception?', Molecular and Cellular Endocrinology, vol 335, no 1 , pp 78 - 88.
  • Sobinoff, A., Mahony, M., Nixon, B., Roman, S. and McLaughlin, E. (2011), 'Understanding the villain : DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling', Toxicological Sciences, vol 123, no 2 , pp 563 - 575.
  • Gunter, K. and McLaughlin, E. (2011), 'Translational control in germ cell development : a role for the RNA-binding proteins Musashi-1 and Musashi-2', IUBMB Life, vol 63, no 9 , pp 678 - 685.
  • Monk, A., Siddall, N., Fraser, B., McLaughlin, E. and Hime, G. (2011), 'Differential roles of HOW in male and female Drosophila germline differentiation', PLoS One, vol 6, no 12 .
  • Monk, A., Siddall, N., Volk, T., Fraser, B., Quinn, L., McLaughlin, E. and Hime, G. (2010), 'HOW is required for stem cell maintenance in the Drosophila testis and for the onset of transit-amplifying divisions', Cell Stem Cell, vol 6, no 4 , pp 348 - 360.
  • Sobinoff, A., Pye, V., Nixon, B., Roman, S. and McLaughlin, E. (2010), 'Adding insult to injury : effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility', Toxicological Sciences, vol 118, no 2 , pp 653 - 666.
  • Yu, D., Ajami, K., Gall, M., Park, J., Lee, S., Evans, K., McLaughlin, E., Pitman, M., Abbott, C., McCaughan, G. and Gorrell, M. (2009), 'The in vivo expression of dipeptidyl peptidases 8 and 9', Journal of Histochemistry & Cytochemistry, vol 57, no 11 , pp 1025 - 1040.
  • McLaughlin, E. and McIver, S. (2009), 'Awakening the oocyte : controlling primordial follicle development', Reproduction, vol 137, no 1 , pp 1 - 11.
  • Nixon, B., Bielanowicz, A., McLaughlin, E., Tanphaichitr, N., Ensslin, M. and Aitken, R. (2009), 'Composition and significance of detergent resistant membranes in mouse spermatozoa', Journal of Cellular Physiology, vol 218, no 1 , pp 122 - 134.
  • Koppers, A., De Luliis, G., Finnie, J., McLaughlin, E. and Aitken, R. (2008), 'Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa', Journal of Clinical Endocrinology and Metabolism, vol 93, no 8 , pp 3199 - 3207.
  • Nixon, B., Aitken, R. and McLaughlin, E. (2007), 'New insights into the molecular mechanisms of sperm-egg interaction', Cellular and Molecular Life Sciences, vol 64, no 14 , pp 1805 - 1823.

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