Professor Chun Guang Li

Professor Chun Guang Li

Professor Pharmacology,
NICM Health Research Institute

Biography

Dr LI has been extensively involved in medical research over the past decades. His current research interests are in the areas of pharmaclology and natural medicines with a particular focus on chemistry, bioactivity and molecular mechanisms of natural products and medicines in various conditions. He has directed a number of research projects and published over 170 articles in peer reviewed journal, and successfully supervised 22 PhDs and 7 Masters students.

 

This information has been contributed by Professor Li.

Qualifications

  • PhD University of Melbourne

Organisational Unit (School / Division)

  • NICM Health Research Institute

Contact

Email: N/A
Phone:
Mobile:
Location:

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Publications

Chapters in Books

  • Bhuyan, D., Perera, S., Kaur, K., Alsherbiny, M., Low, M., Seto, S., Li, C. and Zhou, X. (2020), 'Synergistic effects of Chinese herbal medicine and biological networks', Approaching Complex Diseases: Network-Based Pharmacology and Systems Approach in Bio-Medicine, Springer 9783030328566.
  • Li, C. and Xue, C. (2016), 'Challenges of Chinese herbal medicine', A Comprehensive Guide to Chinese Medicine, World Scientific Press 9789814667074.
  • Li, C., Sheng, S. and May, B. (2012), 'Resources, cultivation, chemistry and biological activities of Salvia miltiorrhiza', Herbs: Cultivation, Medicinal Uses and Enviromental Concerns, Nova Science Publishers 9781619429833.

Journal Articles

  • Zheng, Y., Zhou, X., Chang, D., Bhuyan, D., Zhang, J., Yu, W., Jiang, X., Seto, S., Yeon, S., Li, J. and Li, C. (2020), '[In Press] A novel tri-culture model for neuroinflammation', Journal of Neurochemistry, .
  • Zhou, X., Li, C., Chang, D. and Bensoussan, A. (2019), 'Current status and major challenges to the safety and efficacy presented by Chinese herbal medicine', Medicines, vol 6, no 1 .
  • Zhou, X., Razmovski-Naumovski, V., Kam, A., Chang, D., Li, C., Chan, K. and Bensoussan, A. (2019), 'Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells', BMC Complementary and Alternative Medicine, vol 19 .
  • Ali, M. and Li, C. (2019), 'Medicinal cannabis : potential drug interactions', Medicines, vol 6, no 1 .
  • Ali, M., Abd-Elsalam, W., El badawy, S., Taher, E., Fares, M., Torres, A., Chang, D. and Li, C. (2019), 'Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities : a comprehensive review', Food and Chemical Toxicology, vol 123 , pp 72 - 97.
  • Sharman, M., Verdile, G., Shanmugam, K., Parenti, C., Singh, A., Watt, G., Karl, T., Chang, D., Li, C. and Muench, G. (2019), 'Targeting inflammatory pathways in Alzheimer's disease : a focus on natural products and phytomedicines', CNS Drugs, vol 33, no 5 , pp 457 - 480.
  • Bhuyan, D., Alsherbiny, M., Perera, S., Low, M., Basu, A., Devi, O., Barooah, M., Li, C. and Papoutsis, K. (2019), 'The odyssey of bioactive compounds in avocado (Persea americana) and their health benefits', Antioxidants, vol 8, no 10 .
  • Zheng, Z., Bai, L., O?Loughlan, M., Li, C. and Xue, C. (2019), 'Does electroacupuncture have different effects on peripheral and central sensitization in humans : a randomized controlled study', Frontiers in Integrative Neuroscience, vol 13 .
  • Liu, J., Zhou, X., Meng, Q., Huang, K., Liu, J., Tie, J., Zhuang, R., Chen, G., Zhang, Y., Wei, L., Huang, L., Li, C., Wang, B., Fan, H. and Liu, Z. (2019), 'AFC1 compound attenuated MI/R-induced ventricular remodeling via inhibiting PDGFR and STAT pathway', Frontiers in Pharmacology, vol 10 .
  • Khan, M., Cazzonelli, C., Kurata, H., Li, C., Badsha, M., Muench, G. and Majid, A. (2019), 'Advancing herbal medicine through metabolic pathway analysis in plants and animals for routine pharmacological assessments', Advances in Integrative Medicine, vol 6, no Suppl. 1 , pp 106 - 107.
  • Khan, M., Cazzonelli, C., Kurata, H., Badsha, M., Li, C., Muench, G. and Majid, A. (2019), 'Metabolic similarity of plant and human : implications for efficacy and regulatory compliance of herbal therapies', Australian Herbal Insight, vol 2, no 1 , pp 028 - 037.
  • Suresh, H., Low, M., Jarouche, M., Zheng, G., Zhang, L., Lee, S., Pearson, J., Power, D., Singh, S., Li, C. and Khoo, C. (2018), 'The chemical and pharmacological variability of key bio-actives present in commercially available Angelica sinensis, Glycyrrhiza uralensis and Rhodiola rosea samples', Pharmaceutica Analytica Acta, vol 9, no 10 .
  • Wang, P., Li, C., Cui, D., Qi, Z., Qiu, S., Li, Y. and Ding, S. (2018), 'Effect of exercise induced autophagy on antioxidant defense function of skeletal muscle in mice', Chinese Journal of Sports Medicine, vol 37, no 1 , pp 49 - 56.
  • Fan, X., Li, C. and Wang, P. (2018), 'The regulation of mitochondrial unfolded protein response on the metabolic homeostasis of exercise-induced skeletal muscle', Chinese Journal of Sports Medicine, vol 37, no 4 , pp 353 - 357.
  • Zhai, X., Li, C., Lenon, G., Xue, C. and Li, W. (2017), 'Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones', Asian Journal of Pharmaceutical Sciences, vol 12, no 1 , pp 85 - 97.
  • He, X., Li, C., Zhu, X., Li, Y., Jarouche, M., Bensoussan, A. and Li, P. (2017), 'High-performance liquid chromatography coupled with tandem mass spectrometry technology in the analysis of Chinese medicine formulas : a bibliometric analysis (1997-2015)', Journal of Separation Science, vol 40, no 1 , pp 81 - 92.
  • Bolan, S., Kunhikrishnan, A., Seshadri, B., Choppala, G., Naidu, R., Bolan, N., Ok, Y., Zhang, M., Li, C., Li, F., Noller, B. and Kirkham, M. (2017), 'Souces, distribution, bioavailability, toxicity, and risk assessment of heavy metal(loid)s in complementary medicines', Environment International, vol 108 , pp 103 - 118.
  • Zhou, X., Razmovski-Naumovski, V., Kam, A., Chang, D., Li, C., Bensoussan, A. and Chan, K. (2017), 'Synergistic effects of Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination in angiogenesis behavior in EAhy 926 cells', Medicines, vol 4, no 4 .
  • Zhang, L., Li, C., Liang, H. and Reddy, N. (2017), 'Bioactive mushroom polysaccharides : immunoceuticals to anticancer agents', Journal of Nutraceuticals and Food Science, vol 2, no 2:6 .
  • Wang, P., Li, C., Qi, Z., Cui, D. and Ding, S. (2016), 'Acute exercise stress promotes Ref1/Nrf2 signalling and increases mitochondrial antioxidant activity in skeletal muscle', Experimental Physiology, vol 101, no 3 , pp 410 - 420.
  • Jin, H. and Li, C. (2016), 'Molecular mechanisms of cardioprotective actions of tanshinones', Journal of Chemistry, vol 2016 .
  • Zhai, X., Lenon, G., Xue, C. and Li, C. (2016), 'Euonymus alatus : a review on its phytochemistry and antidiabetic activity', Evidence-Based Complementary and Alternative Medicine, vol 2016 .
  • Zhou, X., Razmovski-Naumovski, V., Chang, D., Li, C., Kam, A., Low, M., Bensoussan, A. and Chan, K. (2016), 'Synergistic effects of Danshen (Salvia Miltiorrhiza Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination in inhibiting inflammation mediators in RAW264.7 cells', BioMed Research International, vol 2016 .
  • Wang, P., Li, C., Qi, Z. and Ding, S. (2016), 'Effect of acute incremental load exercise on SOD activity and mRNA in skeletal muscle of mice', Journal of Chengdu Sport University, vol 42, no 3 , pp 116 - 121.
  • van der Kooy, F., Venkataya, B., Pearson, J., Torres, A., Li, C. and Chang, D. (2015), 'Sensitivity of NMR-based metabolomics in drug discovery from medicinal plants', European Journal of Medicinal Plants, vol 5, no 2 , pp 191 - 203.
  • Wang, P., Li, C., Qi, Z., Cui, D. and Ding, S. (2015), 'Acute exercise induced mitochondrial H2O2 production in mouse skeletal muscle : association with p66Shc and FOXO3a signaling and antioxidant enzymes', Oxidative Medicine and Cellular Longevity, vol 2015 .
  • Li, L., Saigo, N., Zhang, Y., Fanna, D., Shepherd, N., Clegg, J., Zheng, R., Hayami, S., Lindoy, L., Aldrich-Wright, J., Li, C., Reynolds, J., Harman, D. and Li, F. (2015), 'A large spin-crossover [Fe4L4]8+ tetrahedral cage', Journal of Materials Chemistry C, vol 3, no 30 , pp 7878 - 7882.
  • Hamid, K., Alqahtani, A., Kim, M., Cho, J., Cui, P., Li, C., Groundwater, P. and Li, G. (2015), 'Tetracyclic triterpenoids in herbal medicines and their activities in diabetes and its complications', Current Topics in Medicinal Chemistry, vol 15, no 23 , pp 2406 - 2430.
  • Reichel, F., Clegg, J., Gloe, K., Gloe, K., Weigand, J., Reynolds, J., Li, C., Aldrich-Wright, J., Kepert, C., Lindoy, L., Yao, H. and Li, F. (2014), 'Self-assembly of an imidazolate-bridged FeIII/CuII heterometallic cage', Inorganic Chemistry, vol 53, no 2 , pp 688 - 690.
  • Gu, S., Yang, A., Li, C., Lu, C. and Xue, C. (2014), 'Topical application of Chinese herbal medicine for Atopic Eczema : a systematic review with a meta-analysis', Dermatology, vol 228, no 4 , pp 294 - 302.
  • Wang, P., Li, C., Qi, Z. and Ding, S. (2014), 'Roles of c-microRNAs in exercised-induced phenotype change of skeletal muscle', China Sport Science, vol 34, no 9 , pp 66 - 71.
  • Jin, H., Xie, X., Ye, J. and Li, C. (2013), 'TanshinoneIIA and cryptotanshinone protect against hypoxia-induced mitochondrial apoptosis in H9c2 cells', PLoS One, vol 8, no 1 .
  • Jin, H. and Li, C. (2013), 'Tanshinone IIA and cryptotanshinone prevent mitochondrial dysfunction in hypoxia-induced H9c2 Cells : association to mitochondrial ROS, intracellular nitric oxide, and calcium levels', Evid Based Complement Alternat Med, vol 2013 , pp 1 - 11.
  • Olarte, A., Mantri, N., Nugent, G., Wohlmuth, H., Li, C., Xue, C. and Pang, E. (2013), 'A gDNA microarray for genotyping Salvia species', Molecular Biotechnology, vol 54, no 3 , pp 770 - 783.
  • Gu, S., Yang,, A., Xue,, C., Li, C., Pang, ., C., Zhang,, W. and Williams,, H. (2013), 'Chinese herbal medicine for atopic eczema : intervention review', Cochrane Database of Systematic Reviews, vol 9 , pp 1 - 131.
  • Niu, L., Mantri, N., Wohlmuth, H., LI, C., Xue, C. and Pang, E. (2013), 'First report of fingerprinting dried herbal products using a subtractive diversity array', Journal of Complementary and Integrative Medicine, vol 10, no 1 , pp 1 - 11.
  • Shigdar, S., Macdonald, J., O'Connor, M., Wang, T., Xiang, D., Al.Shamaileh, H., Qiao, L., Wei, M., Zhou, S., Zhu, Y., Kong, L., Bhattacharya, S., Li, C. and Duan, W. (2013), 'Aptamers as theranostic agents : modifications, serum stability and functionalisation', Sensors, vol 13, no 10 , pp 13624 - 13637.
  • Mantri, N., Olarte, A., Li, C., Xue, C. and Pang, E. (2012), 'Fingerprinting the asterid species using subtracted diversity array reveals novel species-specific sequences', PLoS One, vol 7, no 4 .
  • Zhou, Z., Xie, X., Zhou, S. and Li, C. (2012), 'Mechanism of reversal of high glucose-induced endothelial nitric oxide synthase uncoupling by tanshinone IIA in human endothelial cell line EA.hy926', European Journal of Pharmacology, vol 697, no 1-3 , pp 97 - 105.
  • Yang, L., Zhou, Z., Chen, X., LI, C., Sneed, K., Liang, J. and Zhou, S. (2012), 'Computational and in vitro studies on the inhibitory effects of herbal compounds on human cytochrome P450 1A2', Xenobiotica, vol 42, no 3 , pp 238 - 255.
  • Mo, S., Liu, W., Li, C., Zhou, Z., Luo, H., Chew, H., Liang, J. and Zhou, S. (2012), 'Pharmacophore, QSAR, and binding mode studies of substrates of human cytochrome P450 2D6 (CYP2D6) using molecular docking and virtual mutations and an application to Chinese herbal medicine screening', Current Pharmaceutical Biotechnology, vol 13, no 9 , pp 1640 - 1704.
  • Mo, S., Liu, W., Chen, Y., Luo, H., Sun, L., Chen, X., Zhou, Z., Sneed, K., Li, C., Du, Y., Liang, J. and Zhou, S. (2012), 'Ligand- and protein-based modeling studies of the inhibitors of human cytochrome P450 2D6 and a virtual screening for potential inhibitors from the Chinese herbal medicine, Scutellaria baicalensis (Huangqin, Baikal Skullcap)', Combinatorial Chemistry & High Throughput Screening, vol 15, no 1 , pp 36 - 80.
  • Lenon, G., Li, K., Chang, Y., Yang, A., Costa da, C., Li, C., Cohen, M., Mann, N. and Xue, C. (2012), 'Efficacy and safety of a Chinese herbal medicine formula (RCM-104) in the management of simple obesity : a randomized, placebo-controlled clinical trial', Evidence-based Complementary and Alternative Medicine, vol 2012 .
  • Li, C. (2012), 'Novel high through-put approach and molecular modelling in drug discovery from natural products and clinical implications', Current Pharmaceutical Biotechnology, vol 13, no 9 , pp 1631 - 1631.
  • Chen, X., Di, Y., Zhang, J., Zhou, Z., Li, C. and Zhou, S. (2012), 'Interaction of herbal compounds with biological targets : a case study with berberine', Scientific World Journal, vol 2012 .
  • Lenon, G., Li, C., Costa, C., Thien, F., Shen, Y. and Xue, C. (2012), 'Lack of efficacy of a herbal preparation (RCM-102) for seasonal allergic rhinitis : a double blind, randomised, placebo-controlled trial', Asia Pacific Allergy, vol 2, no 3 , pp 187 - 194.
  • Li, C., Sheng, S., Pang, E., May, B. and Xue, C. (2011), 'Plant density-dependent variations in bioactive markers and root yield in Australian-grown Salvia miltiorrhiza Bunge', Chemistry & Biodiversity, vol 8, no 4 , pp 699 - 709.
  • Niu, L., Mantri, N., Li, C., Xue, C. and Pang, E. (2011), 'Array-based techniques for fingerprinting medicinal herbs', Chinese Medicine, vol 6 .
  • Wang, L., Liu, Y., Meng, L., Li, C. and Zhou, S. (2011), 'Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes', Basic and Clinical Pharmacology and Toxicology, vol 108, no 2 , pp 94 - 114.
  • Niu, L., Mantri, N., Li, C., Xue, C., Wohlmuth, H. and Pang, E. (2011), 'Detection of Panax quinquefolius in Panax ginseng using 'subtracted diversity array'', Journal of the Science of Food and Agriculture, vol 91, no 7 , pp 1310 - 1315.
  • Liu, Y., Mo, S., Bi, H., Hu, B., Li, C., Wang, Y., Huang, L., Huang, M., Duan, W., Liu, J., Wei, M. and Zhou, S. (2011), 'Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study', Xenobiotica, vol 41, no 4 , pp 259 - 280.
  • Di, Y., Zhou, Z., Li, C. and Zhou, S. (2011), 'Current and future therapeutic targets of rheumatoid arthritis', Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, vol 10, no 2 , pp 92 - 120.
  • He, S., Li, C., Liu, J., Chan, E., Duan, W. and Zhou, S. (2010), 'Disposition pathways and pharmacokinetics of herbal medicines in humans', Current Medicinal Chemistry, vol 17, no 33 , pp 4072 - 4113.
  • Gu, S., Pang, C., Xue, C., Li, C., Yang, A., Zhang, W. and Williams, H. (2010), 'Chinese herbal medicine for atopic eczema (Protocol)', Cochrane Library, , no 8 , pp 1 - 10.
  • Zheng, Z., Feng, S., Costa, C., Li, C., Lu, D. and Xue, C. (2010), 'Acupuncture analgesia for temporal summation of experimental pain : a randomised controlled study', European Journal of Pain, vol 14, no 7 , pp 725 - 731.
  • Lee, Y., Yang, J., Bae, M., Yoo, W., Ye, S., Xue, C. and Li, C. (2010), 'Anti-oxidant and anti-hypercholesterolemic activities of wasabia japonica', Evidence-based Complementary and Alternative Medicine, vol 7, no 4 , pp 459 - 464.
  • Yang, A., Allan, G., Li, C. and Xue, C. (2009), 'Effective application of knowledge management in evidence-based Chinese medicine', Evidence-Based Complementary and Alternative Medicine, vol 6, no 3 , pp 393 - 398.
  • Li, C., Sheng, S., Pang, E., May, B. and Xue, C. (2009), 'HPLC profiles and biomarker contents of Australian-grown Salvia miltiorrhiza f. alba roots', Chemistry & Biodiversity, vol 6, no 7 , pp 1077 - 1086.
  • Li, C., Sheng, S., Pang, E., Marriott, P., May, B., Zhou, S., Story, D. and Xue, C. (2009), 'Cultivar variations of Australian-grown Danshen (Salvia miltiorrhiza) : bioactive markers and root yields', Chemistry & Biodiversity, vol 6, no 2 , pp 170 - 181.
  • Sheng, S., Pang, E., Xue, C. and Li, C. (2009), 'Seasonal variations in bioactive marker contents in Australian-grown Salvia miltiorrhiza roots', Chemistry & Biodiversity, vol 6, no 4 , pp 551 - 560.
  • Lenon, G., Xue, C., Story, D., Thien, F. and Li, C. (2009), 'Inhibition of release of inflammatory mediators in rat peritoneal mast cells and murine macrophages by a Chinese herbal medicine formula (RCM-102)', Phytotherapy Research, vol 23, no 9 , pp 1270 - 1275.
  • Jayasinghe, R., Niu, L., Coram, T., Kong, S., Kaganovitch, J., Xue, C., Li, C. and Pang, E. (2009), 'Effectiveness of an innovative prototype subtracted diversity array (SDA) for fingerprinting plant species of medicinal importance', Planta Medica, vol 75, no 10 , pp 1180 - 1185.
  • Yang, A., Li, C., Costa, C., Allan, G., Reece, J. and Xue, C. (2009), 'Assessing quality of case series studies : development and validation of an instrument by herbal medicine CAM researchers', Journal of Alternative & Complementary Medicine, vol 15, no 5 , pp 513 - 522.
  • May, B., Yang, A., Zhang, L., Owens, M., Bennett, L., Head, R., Cobiac, L., Li, C., Hugel, H., Story, D. and Xue, C. (2009), 'Chinese herbal medicine for mild cognitive impairment and age associated memory impairment : a review of randomised controlled trials', Biogerontology, vol 10, no 2 , pp 109 - 123.
  • May, B., Lit, M., Xue, C., Yang, A., Zhang, L., Owens, M., Head, R., Cobiac, L., Li, C., Hugel, H. and Story, D. (2009), 'Herbal medicine for dementia : a systematic review', Phytotherapy Research, vol 23, no 4 , pp 447 - 459.
  • Liu, Y., Li, C. and Zhou, S. (2009), 'Prediction of deleterious functional effects of non-synonymous single nucleotide polymorphisms in human nuclear receptor genes using a bioinformatics approach', Drug Metabolism Letters, vol 3, no 4 , pp 242 - 286.
  • Shen, Y., Li, C., Zhou, S., Pang, E., Story, D. and Xue, C. (2008), 'Chemistry and bioactivity of Flos Magnoliae, a Chinese herb for rhinitis and sinusitis', Current Medicinal Chemistry, vol 15, no 16 , pp 1616 - 1627.
  • Shen, Y., Pang, E., Xue, C., Zhao, Z., Lin, J. and Li, C. (2008), 'Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells', Phytomedicine, vol 15, no 10 , pp 808 - 814.
  • Di, Y., Li, C., Xue, C. and Zhou, S. (2008), 'Clinical drugs that interact with St. John's wort and implication in drug development', Current Pharmaceutical Design, vol 14, no 17 , pp 1723 - 1742.
  • Zhou, S., Wang, L., Di, Y., Xue, C., Duan, W., Li, C. and Li, Y. (2008), 'Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development', Current Medicinal Chemistry, vol 15, no 20 , pp 1981 - 2039.
  • Zhou, S., Di, Y., Chan, E., Du, Y., Chow, V., Xue, C., Lai, X., Wang, J., Li, C., Tian, M. and Duan, W. (2008), 'Clinical pharmacogenetics and potential application in personalized medicine', Current Drug Metabolism, vol 9, no 8 , pp 738 - 784.
  • Lenon, G., Li, C., Xue, C., Thien, F. and Story, D. (2008), 'Inhibition of inducible nitric oxide production and iNOS protein expression in lipopolysaccharide-stimulated rat aorta and Raw 264.7 macrophages by ethanol extract of a Chinese herbal medicine formula (RCM-101) for allergic rhinitis', Journal of Ethnopharmacology, vol 116, no 3 , pp 547 - 553.
  • Che, Y., Potocnik, S., Ellis, A. and Li, C. (2007), 'Effects of TRIM on tension, intracellular calcium and nitrergic transmission in the rat anococcygeus muscle', Nitric Oxide: Biology and Chemistry, vol 16, no 1 , pp 29 - 35.
  • Zhou, S., Xue, C., Yu, X., Li, C. and Wang, G. (2007), 'Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring', Therapeutic Drug Monitoring, vol 29, no 6 , pp 687 - 710.
  • Jayasinghe, R., Kong, S., Coram, T., Kaganovitch, J., Xue, C., Li, C. and Pang, E. (2007), 'Construction and validation of a prototype microarray for efficient and high-throughput genotyping of angiosperms', Plant Biotechnology Journal, vol 5, no 2 , pp 282 - 289.
  • Lenon, G., Li, C., Xue, C., Thien, F. and Story, D. (2007), 'Inhibition of release of vasoactive and inflammatory mediators in airway and vascular tissues and macrophages by a Chinese herbal medicine formula for allergic rhinitis', Evidence-Based Complementary and Alternative Medicine, vol 4, no 2 , pp 209 - 217.
  • Lenon, G., Xue, C., Story, D., Thien, F., McPhee, S. and Li, C. (2007), 'Inhibition of release of inflammatory mediators in primary and cultured cells by a Chinese herbal medicine formula for allergic rhinitis', Chinese Medicine, vol 2 .
  • Zhou, S., Zhou, Z., Li, C., Chen, X., Yu, X., Xue, C. and Herington, A. (2007), 'Identification of drugs that interact with herbs in drug development', Drug Discovery Today, vol 12, no 15-16 , pp 664 - 673.
  • Li, C., Yang, L. and Zhou, S. (2007), 'Interactions between Chinese herbal medicines and drugs', Australian journal of acupuncture and Chinese medicine, vol 2, no 1 , pp 17 - 24.
  • Guan, S., Bi, H., Pan, Y., Chen, X., Zhou, Z., Xue, C., Li, C., Huang, M. and Zhou, S. (2007), 'Determination of cryptotanshinone, a major active component in Salvia miltiorrhiza, in caco-2 monolayers by HPLC with UV detection', Chromatographia, vol 66, no 7-8 , pp 577 - 582.
  • Yu, X., Lin, S., Zhou, Z., Chen, X., Liang, J., Yu, X., Chowbay, B., Wen, J., Duan, W., Chan, E., Li, X., Cao, J., Li, C., Xue, C. and Zhou, S. (2007), 'Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra', Pharmaceutical Research, vol 24, no 9 , pp 1668 - 1690.
  • Su, Q., He, F., Guan, S., Lu, Y., Gu, L., Huang, Z., Chen, X., Huang, M., Li, C., Chowbay, B. and Zhou, S. (2007), 'High performance liquid chromatography with ultraviolet detection for the determination of SYUIQ-5, a novel telomerase inhibitor for cancer therapy : application to an enzyme kinetic study in rat liver microsomes', Journal of Chromatography B, vol 854, no 1-2 , pp 332 - 337.
  • Cheung, T., Xue, C., Leung, K., Chan, K. and Li, C. (2006), 'Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products - A consequence of inappropriate nomenclature and imprecise labelling?', Clinical Toxicology, vol 44, no 4 , pp 371 - 378.
  • Inthavong, K., Tian, Z., Li, H., Tu, J., Yang, W., Xue, C. and Li, C. (2006), 'A numerical study of spray particle deposition in a human nasal cavity', Aerosol Science and Technology, vol 40, no 11 , pp 1034 - 1045.
  • Xue, C., Li, C., Hugel, H. and Story, D. (2006), 'Does acupuncture or Chinese herbal medicine have a role in the treatment of allergic rhinitis?', Current Opinion in Allergy and Clinical Immunology, vol 6, no 3 , pp 175 - 179.
  • Xue, C., English, R., Zhang, J., Costa, C. and Li, C. (2004), 'The effect of acupuncture on allergic rhinitis : a randomized controlled clinical trial', American Journal of Chinese Medicine, vol 30, no 1 , pp 1 - 11.
  • Xue, C., Thien, F., Zhang, J., Costa, C. and Li, C. (2003), 'Treatment for seasonal allergic rhinitis by Chinese herbal medicine : a randomized placebo controlled trial', Alternative Therapies in Health and Medicine, vol 9, no 5 , pp 80 - 87.
  • Karagiannis, J., Reid, J., Darby, I., Roche, P., Rand, M. and Li, C. (2003), 'Impaired nitric oxide function in the basilar artery of the obese Zucker rat', Journal of Cardiovascular Pharmacology, vol 42, no 4 , pp 497 - 505.
  • Li, C., Karagiannis, J. and Rand, M. (1999), 'Comparison of the redox forms of nitrogen monoxide with the nitrergic transmitter in the rat anococcygeus muscle', British Journal of Pharmacology, vol 127, no 4 , pp 826 - 834.
  • Li, C. and Rand, M. (1999), 'Effects of hydroxocobalamin and carboxy-PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles', British Journal of Pharmacology, vol 127, no 1 , pp 172 - 176.
  • Rand, M. and Li, C. (1995), 'Nitric oxide as a neurotransmitter in peripheral nerves : nature of transmitter and mechanism of transmission', Annual Review of Physiology, vol 57 , pp 659 - 682.
  • Rand, M. and Li, C. (1995), 'Discrimination by the NO-trapping agent, carboxy-PTIO, between NO and the nitrergic transmitter but not between NO and EDRF', British Journal of Pharmacology, vol 116, no 2 , pp 1906 - 1910.
  • Li, C. and Rand, M. (1991), 'Evidence that part of the NANC relaxant response of guinea-pig trachea to electrical field stimulation is mediated by nitric oxide', British Journal of Pharmacology, vol 102, no 1 , pp 91 - 94.
  • Li, C. and Rand, M. (1990), 'Nitric oxide and vasoactive intestinal polypeptide mediate non-adrenergic, non-cholinergic inhibitory transmission to smooth muscle of the rat gastric fundus', European Journal of Pharmacology, vol 191, no 3 , pp 303 - 309.

Conference Papers

  • Kaur, K., Bhuyan, D., Li, C. and Li, F. (2020), 'Modification of curcumin and investigation of its bioactivity', Keystone Symposia: Advances in Cancer Immunotherapy, Online.
  • Bhuyan, D. and Li, C. (2020), 'Antiviral compounds from plants : current trends and future directions', International e-Conference on Nutrients Acquisition by Plants and Plant Based Remedies against Viral Diseases, Assam, India.
  • Wen, J., Inthavong, K., Tian, Z., Tu, J., Xue, C. and Li, C. (2007), 'Airflow patterns in both sides of a realistic human nasal cavity for laminar and turbulent conditions', Australasian Fluid Mechanics Conference, Gold Coast, Qld..

Dr Li has established an international reputation in the fields of complementary medicine research. He has conceptualised and managed various research projects with national and international institutions and industries. His current research interests include chemistry and the bioactivity of natural products and traditional medicines used for treating cardiovascular, cancer, aging and inflammatory conditions. His work involves investigations at various levels from molecular mechanisms to clinical trials.

Areas of Research

Chemical profile and bioactivity of natural products and traditional medicines

Synergy of natural products and food ingredientsDrug discovery

Safety of complementary medicines

This information has been contributed by Professor Li.

Current Projects

Title: Mechanism of synergy of ingredients in natural products and functional foods
Funder:
  • Australian Research Council (ACRG)
  • Integria Healthcare (Australia) Pty Ltd
Western Researchers: Chun Guang Li, Gerald Muench and Vijay Jayasena
Years: 2017-11-16 - 2021-05-15
ID: P00023810
Title: Annual Update of the Nomenclature Compendium for commonly used Chinese herbal medicines
Funder:
  • Australian Health Practitioner Regulation Agency
Western Researchers: Chun Guang Li, Phoebe Zhou and Xiaoshu Zhu
Years: 2018-04-30 - 2022-04-30
ID: P00024727
Title: Combined effects of curcumin and resveratrol on endothelial cell survival against oxidative stress
Funder:
  • NSW Government Health
Western Researchers: Phoebe Zhou and Chun Guang Li
Years: 2019-07-19 - 2022-07-15
ID: P00025954
Title: An investigation of the entourage effect: Synergistic anti-inflammatory interactions between cannabinoids and terpenes in Cannabis
Funder:
  • Cymra Life Sciences Ltd
Western Researchers: Mitchell Low, Deep Bhuyan, Justin Sinclair and Chun Guang Li
Years: 2020-06-29 - 2021-06-29
ID: P00026672
Title: Future Food Systems [Via UNSW]
Funder:
  • Department of Industry, Innovation and Science (CRC)
Western Researchers: Ian Anderson, David Tissue, Priti Krishna, Zhonghua Chen, Oula Ghannoum, Chris Cazzonelli, Mitchell Low, Chun Guang Li, Donald Mcneill and James Cook
Years: 2019-06-30 - 2029-06-01
ID: P00025995

Previous Projects

Title: Synthesis and testing of novel tanshinone analogues
Funder:
  • University of Western Sydney
Western Researchers: Chun Guang Li and Frank Van Der Kooy
Years: 2013-12-09 - 2015-06-30
ID: P00021807
Title: Developing an industry standard for propolis activity
Funder:
  • Department of Industry, Innovation and Science (non ACRG)
  • Homart Pharmaceuticals Pty Ltd
Western Researchers: Chun Guang Li
Years: 2014-07-19 - 2015-05-19
ID: P00022296
Title: Anti-inflammatory activity and synergistic potential of herbal medicines
Funder:
  • University of Western Sydney
  • Integria Healthcare (Australia) Pty Ltd
Western Researchers: Chun Guang Li and Alan Bensoussan
Years: 2015-02-02 - 2016-05-30
ID: P00022377
Title: NICM-BTRT Chinese Medicine Substances: Niu Huang
Funder:
  • Beijing Tong Ren Tang Chinese Medicine Corporation Ltd
Western Researchers: Alan Bensoussan and Chun Guang Li
Years: 2016-07-08 - 2019-12-31
ID: P00024322
Title: NICM- Nomenclature Compendium -Extension 2016
Funder:
  • Australian Health Practitioner Regulation Agency
Western Researchers: Alan Bensoussan, Xiaoshu Zhu and Chun Guang Li
Years: 2016-10-13 - 2017-02-28
ID: P00024344
Title: NICM- Homart Pharmaceuticals Pty Ltd
Funder:
  • Homart Pharmaceuticals Pty Ltd
Western Researchers: Chun Guang Li
Years: 2015-11-11 - 2016-11-23
ID: P00024192

Supervision

Professor Li is available to be a principal supervisor for doctoral projects

Current Supervision

Thesis Title: Ageing-Related Changes in the Senses - Can They Be Delayed by Anti-Aging Medications?
Field of Research:
Thesis Title: In Vivo and In Vitro Assessment of Effluc Transporter Blocking Activity of Crucitin and Genstin and their Antineoplastic Role in Combination with Doxorubicin in Hela Cancer Model of the Mice
Field of Research:
Thesis Title: An Investigation into Efficacy and Action of the Adaptogenic Herbal Remedy Eleutherococcus Senticosus in Treating and Preventing Overtraining Syndrome in Ironman Triathletes
Field of Research:
Thesis Title: The Investigation of the Chemical Variability of Selected Medicinal Herbs and their Associated Pharmacological Effects in Vivo
Field of Research:

Previous Supervision

Thesis Title: Synergistic Behaviour of Salvia and Notoginseng Species in Vascular Diseases
Field of Research: Traditional Chinese Medicine; Biochemistry And Cell Biology; Other Health; Pharmacology
Thesis Title: Finite Nano-scale Metallosupramolecular Assemblies: Design, Synthesis and Applications
Field of Research: Natural And Physical Sciences

Western Sydney University

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Penrith NSW 2751

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