Doctor Simon Myers

Doctor Simon Myers

Senior Lecturer,
Medical Sciences


Dr. Simon Myers completed his PhD in molecular cell biology at the Heart Research Institute in Sydney, where he investigated altered protein expression and activation during atherosclerosis. He then completed a postdoctoral fellow position in molecular virology and host defence in the Department of Pathology at the University of Sydney (USyd) before moving to Apollo Life Sciences as Team Leader, Senior Research Scientist of Cell Biology program. Simon then moved back into medical research by taking up a Senior Research Fellow position at the ANZAC Research Institute, where he led the Cell Biology Program in the Northcott Neuroscience Laboratory. In 2008 Simon was successful in gaining a senior lectureship in Biochemistry at the University of Western Sydney (UWS).

This information has been contributed by Doctor Myers.


  • PhDMed University of Sydney

Organisational Unit (School / Division)

  • Medical Sciences


Phone: (02) 4620 3383
Location: 21.1.05

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Chapters in Books

  • Salih, A., Wormell, P., Garbutcheon-Singh, K., Harper, B., Myers, S., Geny, D., Hammang, C. and Aldrich-Wright, J. (2011), 'Applications of Fluorescence Spectroscopy and Confocal Microscopy.', Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.

Journal Articles

  • Ruprai, H., Shanu, A., Mawad, D., Hook, J., Killian, K., George, L., Wuhrer, R., Houang, J., Myers, S. and Lauto, A. (2020), 'Porous chitosan adhesives with L-DOPA for enhanced photochemical tissue bonding', Acta Biomaterialia, vol 101 , pp 314 - 326.
  • Ruprai, H., Romanazzo, S., Ireland, J., Kilian, K., Mawad, D., George, L., Wuhrer, R., Houang, J., Ta, D., Myers, S. and Lauto, A. (2019), 'Porous chitosan films support stem cells and facilitate sutureless tissue repair', ACS Applied Materials and Interfaces, vol 11, no 36 , pp 32613 - 32622.
  • Sen, M., Almuslehi, M., Gyengesi, E., Myers, S., Shortland, P., Mahns, D. and Coorssen, J. (2019), 'Suppression of the peripheral immune system limits the central immune response following cuprizone-feeding : relevance to modelling Multiple Sclerosis', Cells, vol 8, no 11 .
  • Ng, N., Wu, M., Myers, S. and Aldrich-Wright, J. (2018), 'The in vitro renal cell toxicity of some unconventional anticancer phenanthroline-based platinum(II) complexes', Journal of Inorganic Biochemistry, vol 179 , pp 97 - 106.
  • Frost, S., Mawad, D., Wuhrer, R., Myers, S. and Lauto, A. (2018), 'Semitransparent bandages based on chitosan and extracellular matrix for photochemical tissue bonding', BioMedical Engineering Online, vol 17, no 1 .
  • Shanu, A., Lauto, A. and Myers, S. (2017), 'The role of human coactosin-like protein in neurodegenerative disorders', Biochemistry and Modern Applications, vol 1, no 1 , pp 20 - 24.
  • Shanu, A., Stimpson, S., Coorssen, J. and Myers, S. (2017), 'Autophagy is up regulated in a neuronal model of Charcot-Marie-Tooth disease that overexpresses dynamin 2 mutant', International Journal of Neuroscience Research, vol 1, no 3 .
  • Nguyen, H., Lauto, A., Shanu, A. and Myers, S. (2016), 'Chloride intracellular channel protein 1 and its role in neurodegenerative disorders and cancerous tumors', Biochemistry and Analytical Biochemistry, vol 5, no 1 .
  • Partridge, M., Gopinath, S., Myers, S. and Coorssen, J. (2016), 'An initial top-down proteomic analysis of the standard cuprizone mouse model of multiple sclerosis', Journal of Chemical Biology, vol 9, no 1 , pp 9 - 18.
  • Frost, S., Mawad, D., Higgins, M., Ruprai, H., Kuchel, R., Tilley, R., Myers, S., Hook, J. and Lauto, A. (2016), 'Gecko-inspired chitosan adhesive for tissue repair', NPG Asia Materials, vol 8 .
  • Stimpson, S., Shanu, A., Coorssen, J. and Myers, S. (2016), 'Identifying unique protein alterations caused by SPTLC1 mutations in a transfected neuronal cell model', World Journal of Neuroscience, vol 6, no 4 , pp 325 - 347.
  • Stimpson, S., Lauto, A., Coorssen, J. and Myers, S. (2016), 'Isolation and identification of ER associated proteins with unique expression changes specific to the V144D SPTLC1 mutations in HSN-I', Biochemistry and Analytical Biochemistry, vol 5, no 1 .
  • Stimpson, S., Coorssen, J. and Myers, S. (2015), 'Mitochondrial protein alterations in a familial peripheral neuropathy caused by the V144D amino acid mutation in the sphingolipid protein, SPTLC1', Journal of Chemical Biology, vol 8, no 1 , pp 25 - 35.
  • Partridge, M., Myers, S., Gopinath, S. and Coorssen, J. (2015), 'Proteomics of a conundrum : thoughts on addressing the aetiology versus progression of multiple sclerosis', Proteomics: Clinical Applications, vol 9, no 9-10 , pp 838 - 843.
  • Stimpson, S., Coorssen, J. and Myers, S. (2015), 'Optimal isolation of mitochondria for proteomic analyses', Analytical Biochemistry, vol 475 , pp 1 - 3.
  • Stimpson, S., Coorssen, J. and Myers, S. (2015), 'Proteome alterations associated with the V144D SPTLC1 mutation that causes hereditary sensory neuropathy-I', Electronic Journal of Biology, vol 11, no 4 , pp 176 - 186.
  • Garbutcheon-Singh, K., Harper, B., Myers, S. and Aldrich-Wright, J. (2014), 'Combination studies of platinum(II)-based metallointercalators with buthionine-S,R-sulfoximine, 3-bromopyruvate, cisplatin or carboplatin', Metallomics, vol 6, no 1 , pp 126 - 131.
  • Myers, S., Malladi, C., Hyland, R., Bautista, T., Boadle, R., Robinson, P. and Nicholson, G. (2014), 'Mutations in the SPTLC1 protein cause mitochondrial structural abnormalities and endoplasmic reticulum stress in lymphoblasts', DNA and Cell Biology, vol 33, no 7 , pp 399 - 407.
  • Marshall, L., Stimpson, S., Hyland, R., Coorssen, J. and Myers, S. (2014), 'Increased lipid droplet accumulation associated with a peripheral sensory neuropathy', Journal of Chemical Biology, vol 7, no 2 , pp 67 - 76.
  • Garbutcheon-Singh, K., Leverett, P., Myers, S. and Aldrich-Wright, J. (2013), 'Cytotoxic platinum(II) intercalators that incorporate 1R,2R-diaminocyclopentane', Dalton Transactions, vol 42, no 4 , pp 918 - 926.
  • Garbutcheon-Singh, K., Myers, S., Harper, B., Ng, N., Dong, Q., Xie, C. and Aldrich-Wright, J. (2013), 'The effects of 56MESS on mitochondrial and cytoskeletal proteins and the cell cycle in MDCK cells', Metallomics, vol 5, no 8 , pp 1061 - 1067.
  • Duong, T., Antao, S., Ellis, N., Myers, S. and Witting, P. (2008), 'Supplementation with a synthetic polyphenol limits oxidative stress and enhances neuronal cell viability in response to hypoxia-re-oxygenation injury', Brain Research, vol 1219, no 0 , pp 8 - 18.
  • Rayner, B., Duong, T., Myers, S. and Whitting, P. (2006), 'Protective effect of a synthetic anti-oxidant on neuronal cell apoptosis resulting from experimental hypoxia re-oxygenation injury', Journal of Neurochemistry, vol 97, no 1 , pp 211 - 221.
  • Nicholson, G. and Myers, S. (2006), 'Intermediate forms of charcot-marie-tooth neuropathy: A review', NeuroMolecular Medicine, vol 8, no 40575 , pp 123 - 130.
  • Kok, C., Kennerson, M., Myers, S. and Nicholson, G. (2004), 'Transcript map of the candidate region for HSNI with cough and gastroesophageal reflux on chromosome 3p and exclusion of candidate genes', Neurogenetics, vol 5, no 3 , pp 197 - 200.

Conference Papers

  • Sen, M., Shortland, P., Myers, S., Coorsen, J. and Mahns, D. (2017), 'Treatment with pertussis toxin does not induce a multiple sclerosis-like phenotype in cuprizone-treated mice', Society for Neuroscience. Annual Meeting, Washington, D.C., Wash..

Previous Projects

Title: Identifying common intracellular mechanisms in sensory neuropathies
  • Anonymous Donation
Western Researchers: Simon Myers
Years: 2014-02-19 - 2017-06-30
ID: P00022143
Title: Establishment of a mass spectrometer facility for natural products and proteomics research and teaching at the College of Health and Science within the University of Western Sydney, Campbelltown campus
  • University of Western Sydney
Western Researchers: Nikolaus Sucher, Jens Coorssen, Bill Price, Gerald Muench, Andrew Shalliker, Dennis Chang, Sabine Piller, Simon Myers, Colin Stack and Michelle Moffitt
Years: 2008-09-24 - 2010-09-15
ID: P00016326
Title: Is there a common mechanism shared by distal axonal degenerations?
  • Philip Bushell Foundation
Western Researchers: Simon Myers
Years: 2008-06-25 - 2011-12-24
ID: P00016288
Title: Cell and Protein Analysis Unit
  • University of Western Sydney
Western Researchers: Simon Myers, Jens Coorssen, Sabine Piller, Annemarie Hennessy, Janice Aldrich-Wright, Soon Lee and Gerald Muench
Years: 2009-09-22 - 2010-09-21
ID: P00017371
Title: International Efforts in Translational Medicine
  • University of Western Sydney
Western Researchers: Jens Coorssen, Annemarie Hennessy, Bradley Frankum, Gerald Muench, Joanne Lind, Simon Myers and Soon Lee
Years: 2009-10-28 - 2010-10-27
ID: P00017596
Title: Miltenyi Biotec UWS MMRG PhD Scholarship
  • Miltenyi Biotec Australia Pty Limited
Western Researchers: Simon Myers
Years: 2011-01-01 - 2015-03-31
ID: P00020032


Doctor Myers is available to be a principal supervisor for doctoral projects

Current Supervision

Thesis Title: Investigating SPTLC1 Mutations on Protein and Lipid Profiles in Neuronal Cells
Field of Research:

Western Sydney University

Locked Bag 1797
Penrith NSW 2751

Tel: +61 2 9852 5222

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