Doctor Sabine Piller

Doctor Sabine Piller

DAP - BMedSc & BMedSc, Adv,
Dean's Unit, School of Science

Senior Lecturer,
Medical Sciences


Dr. Sabine C. Piller was born in Vienna, Austria and lived there for 20 years. Coming from a landlocked country, she was always interested in marine biology and completed a MSc degree in marine physiology at the University of Alabama at Birmingham. After working in the Neurophysiology Department at the University of Vienna, Sabine commenced her PhD studies at the John Curtin School of Medical Research at the Australian National University, where she was instrumental in discovering that a protein from HIV had ion channel forming capabilities. Sabine received the Frank Fenner Medal for the best PhD thesis in 1999 and undertook her postdoctoral studies at the Centre for AIDS Research in Birmingham, Alabama before returning to Australia in 2000 as the recipient of a Young Investigator Award from the Centre for Immunology at the St. Vincent?s Hospital in Sydney. In 2003, Sabine relocated her research group to the Westmead Millennium Institute where she headed the HIV Protein Functions Group. Sabine joined the University of Western Sydney (UWS) in 2008 as a Senior Lecturer in Physiology in the School of Biomedical and Health Sciences and has since established an active research team. Sabine also holds an Adjunct Position in the School of Medicine at UWS.

This information has been contributed by Doctor Piller.


  • PhD The Australian National University

Organisational Unit (School / Division)

  • Dean's Unit, School of Science
  • Medical Sciences


Phone: (02) 4620 3354
Location: 21.1.08

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Journal Articles

  • Plett, K., Raposo, A., Anderson, I., Piller, S. and Plett, J. (2019), 'Protein arginine methyltransferase expression affects ectomycorrhizal symbiosis and the regulation of hormone signaling pathways', Molecular Plant-Microbe Interactions, vol 32, no 10 , pp 1291 - 1302.
  • Raposo, A. and Piller, S. (2018), 'Protein arginine methylation : an emerging regulator of the cell cycle', Cell Division, vol 13, no 1 .
  • Plett, K., Raposo, A., Bullivant, S., Anderson, I., Piller, S. and Plett, J. (2017), 'Root morphogenic pathways in Eucalyptus grandis are modified by the activity of protein arginine methyltransferases', BMC Plant Biology, vol 17 .
  • Barton, M., Morley, J., Stoodley, M., Ng, K., Piller, S., Duong, H., Mawad, D., Mahns, D. and Lauto, A. (2013), 'Laser-activated adhesive films for sutureless median nerve anastomosis', Journal of Biophotonics, vol 6, no 11-12 , pp 938 - 949.
  • Nguyen, N., Ooi, L., Piller, S. and Muench, G. (2013), 'Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a', Molecular Nutrition and Food Research, vol 57, no 11 , pp 1901 - 1907.
  • Barton, M., Piller, S., Mahns, D., Morley, J., Mawad, D., Longo, L. and Lauto, A. (2012), 'In vitro cell compatibility study of rose bengal-chitosan adhesives', Lasers in Surgery and Medicine, vol 44, no 9 , pp 762 - 768.
  • Mirto, L. and Piller, S. (2010), 'Protein arginine methylation: A pivotal factor and a target for novel HIV-therapeutics, other viruses and multiple diseases', HIV Therapy, vol 4, no 1 , pp 65 - 81.
  • Lauto, A., Mawad, D., Barton, M., Gupta, A., Piller, S. and Hook, J. (2010), 'Photochemical tissue bonding with chitosan adhesive films', BioMedical Engineering Online, vol 9 .
  • Caly, L., Jans, D. and Piller, S. (2009), 'Proteolytic cleavage of HIV-1 GFP-Vpr fusions at vovel sites within virions and living cells: Concerns for intracellular trafficking studies', Journal of Fluorescence, vol 19, no 3 , pp 567 - 573.
  • Caly, L., Saksena, N., Piller, S. and Jans, D. (2008), 'Impaired nuclear import and viral incorporation of Vpr derived from a HIV long-term non-progressor', Retrovirology, vol 5 .
  • Hearps, A., Wagstaff, K., Piller, S. and Jans, D. (2008), 'The N-terminal basic domain of the HIV-1 matrix protein does not contain a conventional nuclear localization sequence but is required for DNA binding and protein self-association', Biochemistry, vol 47, no 7 , pp 2199 - 2210.
  • Hearps, A., Pryor, M., Kuusisto, H., Rawlinson, S., Piller, S. and Jans, D. (2007), 'The biarsenical dye lumio exhibits a reduced ability to specifically detect tetracysteine-containing proteins within live cells', Journal of Fluorescence, vol 17, no 6 , pp 593 - 597.
  • Willemsen, N., Hitchen, E., Bodetti, T., Apolloni, A., Warrilow, D., Piller, S. and Harrich, D. (2006), 'Protein methylation is required to maintain optimal HIV-1 infectivity', Retrovirology, vol 3 .
  • Micoli, K., Mamaeva, O., Piller, S., Barker, L., Pan, G., Hunter, E. and McDonald, J. (2006), 'Point mutations in the C-terminus of HIV-1 gp160 reduce apoptosis and calmodulin binding without affecting viral replication', Virology, vol 344, no 2 , pp 468 - 479.
  • Cali, L., Wang, B., Mikhail, M., Gill, M., Beckthold, B., Salemi, M., Jans, D., Piller, S. and Saksena, N. (2005), 'Evidence for host-driven selection of the HIV type 1 vpr gene in vivo during HIV disease progression in a transfusion-acquired cohort', AIDS Research and Human Retroviruses, vol 21, no 8 , pp 728 - 733.
  • Piller, S., Caly, L. and Jans, D. (2003), 'Nuclear import of the pre-integration complex (PIC): The Achilles heel of HIV?', Current Drug Targets, vol 4, no 5 , pp 409 - 429.
  • Krichevsky, A., Graessmann, A., Nissim, A., Piller, S., Zakai, N. and Loyter, A. (2003), 'Antibody fragments selected by phage display against the nuclear localization signal of the HIV-1 Vpr protein inhibit nuclear import in permeabilized and intact cultured cells', Virology, vol 305, no 1 , pp 77 - 92.
  • Jones, D., Suzuki, K. and Piller, S. (2002), 'A 100-amino acid truncation in the cytoplasmic tail of glycoprotein 41 in the reference HIV type 1 strain RF', AIDS Research and Human Retroviruses, vol 18, no 7 , pp 513 - 517.
  • Piller, S., Perrin, M. and Jossen, A. (2001), 'Methods for state-of-charge determination and their applications', Journal of Power Sources, vol 96, no 1 , pp 113 - 120.

Conference Papers

  • Lauto, A., Mawad, D., Barton, M., Piller, S. and Longo, L. (2011), 'Chitosan adhesive films for photochemical tissue bonding', Annual Congress of the International Academy Laser Medicine and Surgery, Florence, Italy.
  • Lauto, A., Mawad, D., Barton, M., Piller, S. and Longo, L. (2011), 'Chitosan adhesive films for photochemical tissue bonding', Annual Congress of the International Academy Laser Medicine and Surgery, Florence, Italy.

Previous Projects

Title: Establishment of a mass spectrometer facility for natural products and proteomics research and teaching at the College of Health and Science within the University of Western Sydney, Campbelltown campus
  • University of Western Sydney
Western Researchers: Nikolaus Sucher, Jens Coorssen, Bill Price, Gerald Muench, Andrew Shalliker, Dennis Chang, Sabine Piller, Simon Myers, Colin Stack and Michelle Moffitt
Years: 2008-09-24 - 2010-09-15
ID: P00016326
Title: Cell and Protein Analysis Unit
  • University of Western Sydney
Western Researchers: Simon Myers, Jens Coorssen, Sabine Piller, Annemarie Hennessy, Janice Aldrich-Wright, Soon Lee and Gerald Muench
Years: 2009-09-22 - 2010-09-21
ID: P00017371


Doctor Piller is available to be a principal supervisor for doctoral projects

Current Supervision

Thesis Title: The Functional Role of Methylated Proteins in Neurons
Field of Research:
Thesis Title: Impacts of AMPK Activators and Metal Stressors on Energy Levels of Neuro 2a Cells
Field of Research: General Medicine

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