Doctor Jerry Zhou
Postdoctoral Research Fellow in Translational Gastroenterology,
School of Medicine
Biography
Dr Jerry Zhou has over 10 years of experience in translational research. His PhD at University of Sydney involved the development of a "lab-on-a chip" with USYD spin-off company Medsaic. Dr Zhou joined Western Sydney University, School of Medicine, in February of 2014 as a postdoctoral research fellow to work in translational gastroenterology. The laboratory, under his management, has grown to produce internationally recognised research on gut microbiome, gastrointestinal motility, nutrition and dietetics, and regenerative therapy as well as collaborations with research teams at John Hunter Hospital, Swinburne University, University of New South Wales, and University of Technology Sydney.
Dr Jerry Zhou is a clinical research fellow at gastrointestinal physiology clinics in the Greater Western Sydney region (at Blacktown and Camden Hospitals). The clinical experience has bridged the divide between clinical and basic science, creating relevant research questions and the translation of research outcomes back into clinical practice.
The Gut Motility Network has grown to incorporate community engagement and promotion of gut motility disorders as core themes. Dr Zhou has established partnerships with advocacy groups Rotary Health Australia, Rotary Devonport and Oesopahgeal Cancer Awareness Group Inc. (OCAGI). He also created and manages university-affiliated website (https://www.westernsydney.edu.au/gimotility) and a patient advocacy group Gastroparesis Australia (http://www.gastroparesisaustralia.com/).
Dr Zhou leads the team in MedTech development, his an active member of National Smart Sensing Network (NSSN) and Health, Education, Research and Enterprise (SPHERE). He completed the Cicada Innovation/NSW Health Medical Device Commercialisation Training Program, winning Product Development Award and People’s Choice Award. He is the inventor and patent holder of In & Out Trainer (an at home anorectal biofeedback therapy device) and nano-endoscopy (an oesophageal cancer screening system). Dr Zhou has successfully securing several competitive grants, philanthropic and industry funding for the commercialisation of these technologies.
This information has been contributed by Doctor Zhou.
Qualifications
- PhD University of Sydney
- BSc University of Sydney
Organisational Unit (School / Division)
- School of Medicine
Committees
- Oesopahgeal Cancer Awareness Group Inc.
- National Smart Sensing Network (NSSN)
- Gastroparesis Australia
- Health, Education, Research and Enterprise (SPHERE)
Contact
| Email: | J.Zhou@westernsydney.edu.au |
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| Phone: | (02) 4620 3865 |
| Mobile: | 0422046095 |
| Location: | 30.2.65 Campbelltown |
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Publications
Chapters in Books
- Belov, L., Hallal, S., Matic, K., Zhou, J., Wissmueller, S., Ahmed, N., Tanjil, S., Mulligan, S., Best, O., Simpson, R. and Christopherson, R. (2017), 'Surface profiling of extracellular vesicles from plasma or ascites fluid using DotScan antibody microarrays', Serum/Plasma Proteomics: Methods and Protocols, Springer 9781493970568.
- Zhou, J., Belov, L., Armstrong, N. and Christopherson, R. (2013), 'Antibody microarrays and multiplexing', Bioinformatics of Human Proteomics, Springer 9789400758100.
- Belov, L., Zhou, J. and Christopherson, R. (2012), 'Colorectal cancer therapeutic antibodies', Encyclopaedia of Cancer, Springer 9783642164828.
Journal Articles
- Foong, D., Mikhael, M., Zhou, J., Zarrouk, A., Liu, X., Schroder, J., Polo, J., Ho, V. and O'Connor, M. (2023), 'Transcriptome and proteome profiling of primary human gastric interstitial cells of Cajal predicts pacemaker networks', Journal of Neurogastroenterology and Motility, vol 29, no 2 , pp 238 - 249.
- Zhou, J., Ho, V. and Javadi, B. (2022), 'New Internet of Medical Things for home-based treatment of anorectal disorders', Sensors, vol 22, no 2 .
- Foong, D., Liyanage, L., Zhou, J., Zarrouk, A., Ho, V. and O'Connor, M. (2022), 'Single-cell RNA sequencing predicts motility networks in purified human gastric interstitial cells of Cajal', Neurogastroenterology and Motility, vol 34, no 7 .
- Suresh, H., Mikhael, M., Ho, V. and Zhou, J. (2022), 'A HPLC-ESI-Q-ToF-MS method for the analysis of monomer constituents in PHGG, gum arabic and psyllium husk prebiotic dietary fibre supplements', International Journal of Food Properties, vol 25, no 1 , pp 1650 - 1667.
- Suresh, H., Zhou, J. and Ho, V. (2021), 'The short-term effects and tolerability of low-viscosity soluble fibre on gastroparesis patients : a pilot clinical intervention study', Nutrients, vol 13, no 12 .
- Zhou, J., Teo, M., Ho, V. and Brannan, J. (2020), 'Prevalence and effects of gastro-oesophageal reflux during spirometry in subjects undergoing reflux assessment', PLoS One, vol 15, no 2 .
- Foong, D., Zhou, J., Zarrouk, A., Ho, V. and O'Connor, M. (2020), 'Understanding the biology of human interstitial cells of Cajal in gastrointestinal motility', International Journal of Molecular Sciences, vol 21, no 12 .
- Zhou, J., Shrestha, P., Qiu, Z., Harman, D., Teoh, W., Al-Sohaily, S., Liem, H., Turner, I. and Ho, V. (2020), 'Distinct microbiota dysbiosis in patients with non-erosive reflux disease and esophageal adenocarcinoma', Journal of Clinical Medicine, vol 9, no 7 .
- Suresh, H., Ho, V. and Zhou, J. (2020), 'Rheological characteristics of soluble fibres during chemically simulated digestion and their suitability for gastroparesis patients', Nutrients, vol 12, no 8 .
- Zhou, J., Jameson, C. and Ho, V. (2019), 'High-amplitude gastric contractions following laparoscopic sleeve gastrectomy', Case Reports in Surgery, vol 2019 .
- Fragakis, A., Zhou, J., Mannan, H. and Ho, V. (2018), 'Association between drug usage and constipation in the elderly population of Greater Western Sydney Australia', International Journal of Environmental Research and Public Health, vol 15, no 2 .
- Brannan, J., Zhou, J., Ho, V. and Teo, M. (2018), 'Gastric-oesphageal (GOR) reflux during spirometry : prevalence and effects (Poster)', Respirology, vol 23, no Suppl. 1 , pp 11 - 11.
- Zhou, J., Sykes, C. and Ho, V. (2018), 'Semi-solid and solid bolus swallows in high-resolution oesophageal manometry for the detection of motility disorders', Open Journal of Gastroenterology, vol 8, no 1 .
- Wong, K., Tang, L., Zhou, J. and Ho, V. (2017), 'Analysis of spatiotemporal pattern and quantification of gastrointestinal slow waves caused by anticholinergic drugs', Organogenesis, vol 13, no 2 , pp 39 - 62.
- Zhou, J., O'Connor, M. and Ho, V. (2017), 'The potential for gut organoid derived interstitial cells of Cajal in replacement therapy', International Journal of Molecular Sciences, vol 18, no 10 .
- Teo, M., Zhou, J., Ho, V. and Brannan, J. (2017), 'Gastro-oesophageal reflux (GOR) during spirometry : prevalence and effects', European Respiratory Journal, vol 50, no Suppl 61 .
- Zhou, J., Belov, L., Chapuis, P., Chan, C., Armstrong, N., Kaufman, K., Solomon, M., Clarke, S. and Christopherson, R. (2015), 'Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories', Journal of Immunological Methods, vol 416 , pp 59 - 68.
- Meng, W., Zhou, J., Elliott, R., Murphy, P., Ho, V. and O'Connor, M. (2015), 'Is there a role for human pluripotent stem cells in modelling interstitial cells of cajal and gut motility disorders?', Current Stem Cell Research & Therapy, vol 10, no 3 , pp 251 - 257.
- Chik, J., Zhou, J., Moh, E., Christopherson, R., Clarke, S., Molloy, M. and Packer, N. (2014), 'Comprehensive glycomics comparison between colon cancer cell cultures and tumours : implications for biomarker studies', Journal of Proteomics, vol 108 , pp 146 - 162.
- Belov, L., Zhou, J. and Christopherson, R. (2011), 'Cell surface markers in colorectal cancer prognosis', International Journal of Molecular Sciences, vol 12, no 1 , pp 78 - 113.
- Zhou, J., Belov, L., Solomon, M., Chan, C., Clarke, S. and Christopherson, R. (2011), 'Colorectal cancer cell surface protein profiling using an antibody microarray and fluorescence multiplexing', Journal of Visualized Experiments, , no 55Article Number e3322 .
- Zhou, J., Belov, L., Huang, P., Shin, J., Solomon, M., Chapuis, P., Bokey, E. and Chan, C. (2010), 'Surface antigen profiling of colorectal cancer using antibody microarrays with fluorescence multiplexing', Journal of Immunological Methods, vol 355, no 40575 , pp 40 - 51.
Conference Papers
- Shin, J., Zhou, J., Belov, L., Zhang, M., Hong, A., Solomon, M., Christopherson, R. and Lee, S. (2009), 'Comparison of Radiosensitivity and Cell Membrane Proteome between Microsatellite stable and unstable colorectal cancers - an In Vitro study with A 122 antibody microarray', RCPA Pathology Update, Sydney.
Current Projects
| Title: | Prebiotic effects of partially hydrolysed guar gum in individuals with gastropareses |
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| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2022-06-23 - 2025-06-23 |
| ID: | P00028592 |
| Title: | Prebiotic effects of partially hydrolysed guar gum in irritable bowel syndrome patients |
| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2022-04-30 - 2023-10-31 |
| ID: | P00027868 |
Previous Projects
| Title: | Effect of low viscosity soluble fibre on gastroparesis symptoms in patients with gastroparesis |
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| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2016-08-26 - 2021-12-01 |
| ID: | P00023596 |
| Title: | The effects of aging and anticholinergic treatment on gastrointestinal motility |
| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2014-09-16 - 2015-12-16 |
| ID: | P00022356 |
| Title: | Characterising the role of interstitial cells of Cajal (ICC) in human stem cell-derived gut organoids |
| Funder: |
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| Western Researchers: | Michael O'Connor, Jerry Zhou and Vincent Ho |
| Years: | 2018-03-05 - 2021-03-05 |
| ID: | P00024921 |
| Title: | Continuous optical and pH monitoring device for the distal oesophagus |
| Funder: |
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| Western Researchers: | Jerry Zhou, Vincent Ho and Gu Fang |
| Years: | 2019-09-16 - 2021-03-31 |
| ID: | P00026057 |
| Title: | Clinical trial of a new Internet-of-Medical-Things device for home-based treatment of anorectal disorders |
| Funder: |
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| Western Researchers: | Jerry Zhou, Vincent Ho and Bahman Javadi Jahantigh |
| Years: | 2021-09-01 - 2022-07-31 |
| ID: | P00027428 |
| Title: | A pilot study on the effects of mushroom juice consumption in individuals with irritable bowel disorders |
| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2021-02-01 - 2022-09-30 |
| ID: | P00026948 |
| Title: | Comparative gastric transit study in gastroparesis and slow transit constipation |
| Funder: |
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| Western Researchers: | Jerry Zhou and Vincent Ho |
| Years: | 2021-05-24 - 2023-03-31 |
| ID: | P00027305 |
Supervision
Current Supervision
| Thesis Title: | Breath test screening for the early detection of Oesophageal Cancer |
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| Field of Research: | |
| Thesis Title: | Proteotyping microorganisms in human distal oesaphagus under normal and disease conditions |
| Field of Research: | |
| Thesis Title: | Developing a New Evidence-Based E-Learning Program to Improve the Knowledge of Junior Nurses and Nursing Students and their Attitudes Towards Caring for Patients with Colorectal Cancer |
| Field of Research: | |
| Thesis Title: | Characterising the role of interstitial cells of Cajal (ICC) in human stem cell-derived gut organoids |
| Field of Research: | |
| Thesis Title: | Effect of Low Viscosity Soluble Fiber on Gastroparesis Symptoms in Patients with Gastroparesis |
| Field of Research: | |
| Thesis Title: | Continuous Endoscopy: Optical and pH Monitoring of the Distal Oesophagus |
| Field of Research: |
Media
| Title: | The Conversation |
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| Description: | Curious Kids article |