Doctor Cherylea Browne

Senior Lecturer - Human Anatomy,
Physical Sciences

Biography
Contact
Publications
Projects
Supervision
Teaching
Media

Biography

Dr Cherylea Browne is a Senior Lecturer in Human Anatomy within the School of Science, Western Sydney University, and an Adjunct Senior Lecturer within the School of Medical Sciences, Faculty of Medicine, UNSW Sydney. Her research focuses on a rare vestibular disorder called Mal de Debarquement Syndrome and understanding the underlying mechanisms of this disorder to develop novel treatment protocols. Cherylea is also involved in concussion/mild traumatic brain injury research and cochlear gene therapy.

In 2007, Cherylea completed a Bachelor of Medical Science with honours at The University of Sydney. Her honours research in the Sudden Infant Death Syndrome (SIDS) Neuropathology Laboratory involved investigating the effects of post-natal nicotine exposure on autonomic regulation centres in the brainstem. Cherylea then completed a PhD in 2013 at the School of Medicine, Western Sydney University. She investigated the effects of noise-induced hearing loss on central auditory processing. In 2012-2014, Cherylea conducted gene therapy research in the Translational Neuroscience Facility at UNSW Sydney, and subsequently was appointed as Associate Lecturer in the Department of Physiology. Cherylea was appointed as Lecturer in Human Anatomy at the Western Sydney University in early 2014 and continues to maintain a strong research collaboration with the Translational Neuroscience Facility. In 2015, Cherylea was appointed as a Conjoint Lecturer within the School of Medical Sciences, Faculty of Medicine, UNSW Sydney. Cherylea founded the Mal de Debarquement Syndrome (MdDS) Research group in 2017 and collaborates with MdDS experts at Mt Sinai Hospital - New York, United States of America, Prince of Wales Private Hospital - Sydney, Australia, and Antwerp University Hospital - Antwerp, Belgium. Cherylea has conducted various studies on MdDS patients in the hope to elucidate the underlying mechanisms of the disorder. Recently, her research interests have expanded into vestibular and oculomotor deficits in concussion / mild traumatic brain injury with an industry linked project. Cherylea is on the Advisory Medical Board for MdDS Australia and is the coordinator for the NSW Australian Brain Bee Challenge.

Over the past 15 years, Cherylea has taught anatomy and physiology across various disciplines and educational institutions. She is the unit coordinator for Human Anatomy and Physiology 2 (HAP2), and teaches into Human Anatomy and Physiology 1, and Anatomy of the Head and Neck.

This information has been contributed by Doctor Browne.

Qualifications

PhD University of Western Sydney
BMDSC (Hons) University of Sydney

Professional Memberships

Australian Neuroscience Society (2008 - 2009)
Australasian Neuroscience Society (2010 - 2012)
Australasian Neuroscience Society (2016 - 2017)
Association for Research in Otolaryngology (2012 - 2013)

Awards

School of Science and Health CILT Grant (with Dr Manisha Dayal) 2016-05-16
School of Science and Health CILT Grant (with Dr Manisha Dayal and Dr Hayley Green) 2016-05-16
UWS Researcher Development Strategic Initiative Funding 2015-07-03
School of Science and Health Research Seed Grant (ECR Category) 2014-05-21
School of Science and Health CILT Grant (with Dr Manisha Dayal) 2015-05-11
School of Science and Health ECR Grant 2015-04-21
School of Science and Health Research ECR Grant 2016-05-11
School of Science and Health CILT Grant 2016-05-16
Western Sydney University Strategic Initiative Funding - Career Interruption Grant 2018-11-01
Western Sydney University Strategic Initiative Funding - ECR Grant 2017-01-01

Interests

Mal de Debarquement Syndrome
Auditory Neuroscience
Cochlear Implant
Gene Therapy
MdDS
Motion Sickness
Neuritogenesis
Vestibular Neuroscience

Organisational Unit (School / Division)

Physical Sciences

Committees

MdDS Australia
Australian Brain Bee Challenge

Contact

Email:	C.Browne@westernsydney.edu.au
Phone:	(02) 4620 3491
Mobile:
Location:	21.1.12 Campbelltown

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Teaching

Previous Teaching Areas

300322 Neuroanatomy, 2012
300751 Anatomy of the Thorax and Abdomen, 2016
300754 Neuroanatomy, 2015
300754 Neuroanatomy, 2016
300825 Introduction to Anatomy, 2012
300892 Medical Science Project, 2015
300897 Anatomy of the Head and Neck, 2015
300897 Anatomy of the Head and Neck, 2016
300910 Advanced Science Project C, 2017
300937 Advanced Science Project A, 2015
300937 Advanced Science Project A, 2018
400868 Human Anatomy and Physiology 1, 2014
400868 Human Anatomy and Physiology 1, 2015
400868 Human Anatomy and Physiology 1, 2016
400868 Human Anatomy and Physiology 1, 2017
400868 Human Anatomy and Physiology 1, 2018
400868 Human Anatomy and Physiology 1, 2020
400868 Human Anatomy and Physiology 1, 2021
400869 Human Anatomy and Physiology 2, 2011
400869 Human Anatomy and Physiology 2, 2012
400869 Human Anatomy and Physiology 2, 2014
400869 Human Anatomy and Physiology 2, 2015
400869 Human Anatomy and Physiology 2, 2016
400869 Human Anatomy and Physiology 2, 2017
400869 Human Anatomy and Physiology 2, 2019
400869 Human Anatomy and Physiology 2, 2020
400869 Human Anatomy and Physiology 2, 2021
400881 Functional Anatomy, 2011
NATS1009 Human Anatomy and Physiology 1, 2022
NATS1010 Human Anatomy and Physiology 2, 2022

Publications

Chapters in Books

Housley, G., Browne, C., Crawford, E., Klugmann, M., Lovell, N. and Pinyon, J. (2016), 'Cochlear implant close-field electroporation', Handbook of Electroporation, Springer 9783319267791.

Journal Articles

Browne, C., Sheeba, S., Astill, T., Baily, A., Deblieck, C., Mucci, V. and Cavaleri, R. (2024), '[In Press] Assessing the synergistic effectiveness of intermittent theta burst stimulation and the vestibular ocular reflex rehabilitation protocol in the treatment of Mal de Debarquement Syndrome : a randomised controlled trial', Journal of Neurology, .
Burlando, B., Mucci, V., Browne, C., Losacco, S., Indovina, I., Marinelli, L., Blanchini, F. and Giordano, G. (2023), 'Mal de Debarquement Syndrome explained by a vestibulo-cerebellar oscillator', Mathematical Medicine and Biology, vol 40, no 1 , pp 96 - 110.
Sheeba, S., Cavaleri, R., Summers, S. and Browne, C. (2023), 'Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms : protocol for a systematic review and meta-analysis', BMJ Open, vol 13, no 1 .
Mucci, V., Demori, I., Browne, C., Deblieck, C. and Burlando, B. (2023), 'Fibromyalgia in pregnancy : neuro-endocrine fluctuations provide insight into pathophysiology and neuromodulation treatment', Biomedicines, vol 11, no 2 .
Mucci, V., Hamid, M., Jacquemyn, Y. and Browne, C. (2022), 'Influence of sex hormones on vestibular disorders', Current Opinion in Neurology, vol 35, no 1 , pp 135 - 141.
Mucci, V., Demori, I., Rapallo, F., Molinari, E., Losacco, S., Marinelli, L., Browne, C. and Burlando, B. (2022), 'Vestibular disability/handicap in Fibromyalgia : a questionnaire study', Journal of Clinical Medicine, vol 11, no 4 .
Browne, C., Fahey, P., Sheeba, S., Sharpe, M., Rosner, M., Feinberg, D. and Mucci, V. (2022), 'Visual disorders and mal de debarquement syndrome : a potential comorbidity questionnaire-based study', Future Science OA, vol 8, no 7 .
Baptiste, Y., Abramovich, S. and Browne, C. (2021), 'Measuring the value of a digital supplemental resource', Advances in Physiology Education, vol 45, no 4 , pp 685 - 693.
Seehusen, C., Mucci, V., Welman, K., Browne, C., Feletti, F. and Provance, A. (2020), 'Review on reported concussion, identification and management in extreme sports', Muscle, Ligaments and Tendons Journal, vol 10, no 2 , pp 290 - 299.
Mucci, V., Indovina, I., Browne, C., Blanchini, F., Giordano, G., Marinelli, L. and Burlando, B. (2020), 'Mal de Debarquement Syndrome : a matter of loops?', Frontiers in Neurology, vol 11 .
Browne, C. (2019), 'Assessing the engagement rates and satisfaction levels of various clinical health science student sub-groups using supplementary elearning resources in an introductory anatomy and physiology unit', Health Education, vol 119, no 1 , pp 2 - 17.
Mucci, V., Canceri, J., Jacquemyn, Y., Ombergen, A., Maes, L., Heyning, P. and Browne, C. (2019), 'Pilot study on patients with Mal de Debarquement syndrome during pregnancy', Future Science, vol 5, no 4 .
Mucci, V., Canceri, J., Brown, R., Dai, M., Yakushin, S., Watson, S., Ombergen, A., Topsakal, V., Heyning, P., Wuyts, F. and Browne, C. (2018), 'Mal de Debarquement Syndrome : a survey on subtypes, misdiagnoses, onset and associated psychological features', Journal of Neurology, vol 265, no 3 , pp 486 - 499.
Mucci, V., Canceri, J., Brown, R., Dai, M., Yakushin, S., Watson, S., Ombergen, A., Jacquemyn, Y., Fahey, P., Heyning, P., Wuyts, F. and Browne, C. (2018), 'Mal de Debarquement syndrome : a retrospective online questionnaire on the influences of gonadal hormones in relation to onset and symptom fluctuation', Frontiers in Neurology, vol 9 .
Mucci, V., Jacquemyn, Y., Ombergen, A., Heyning, P. and Browne, C. (2018), 'A new theory on GABA and calcitonin gene-related peptide involvement in MdDs predisposition factors and pathophysiology', Medical Hypotheses, vol 120 , pp 128 - 134.
Mucci, V., Perkisas, T., Jillings, S., Rompaey, V., Ombergen, A., Fransen, E., Vereeck, L., Wuyts, F., Heyning, P. and Browne, C. (2018), 'Sham-controlled study of optokinetic stimuli as treatment for Mal de Debarquement Syndrome', Frontiers in Neurology, vol 9 .
Canceri, J., Brown, R., Watson, S. and Browne, C. (2018), 'Examination of current treatments and symptom management strategies used by patients with Mal De Debarquement Syndrome', Frontiers in Neurology, vol 9 .
Browne, C., Pinyon, J., Housley, D., Crawford, E., Lovell, N., Klugmann, M. and Housley, G. (2016), 'Mapping of bionic array electric field focusing in plasmid DNA-based gene electrotransfer', Gene Therapy, vol 23, no 4 , pp 369 - 379.
Browne, C., Morley, J. and Parsons, C. (2012), 'Tracking the expression of excitatory and inhibitory neurotransmission-related proteins and neuroplasticity markers after noise induced hearing loss', PLoS One, vol 7, no 3 .
Browne, C., Sharma, N., Waters, K. and Machaalani, R. (2010), 'The effects of nicotine on the alpha-7 and beta-2 nicotinic acetycholine receptor subunits in the developing piglet brainstem', International Journal of Developmental Neuroscience, vol 28, no 1 , pp 1 - 7.

Conference Papers

Browne, C., Ratanapongleka, M., Muench, G., Parsons, C. and Morley, J. (2012), 'Alpha Lipoic Acid and noise induced hearing loss : a prevention and treatment trial', Association for Research in Otolaryngology Annual Midwinter Research Meeting, San Diego, Calif..
Parsons, C., Browne, C., Chen, S. and Morley, J. (2011), 'Tracking neuronal changes in the auditory system following noise-induced hearing loss', Association for Research in Otolaryngology. Annual Midwinter Research Meeting, Baltimore, Md..
Browne, C., Morley, J. and Parsons, C. (2011), 'Tracking the expression of GABAA receptor subunit a1, Glutamic-Acid Decarboxylase-67, N-Methyl-D-Aspartate receptor subunit 2A in rat auditory pathway following noise-induced hearing loss', Association for Research in Otolaryngology Annual Midwinter Research Meeting, Baltimore, Md..
Parsons, C., Calford, M., Browne, C. and Morley, J. (2009), 'Tracking tonotopic changes in the auditory system following noise-induced hearing loss', Society for Neuroscience. Meeting, Chicago, Ill..
Browne, C., Morley, J. and Parsons, C. (2009), 'Tracking the expression of GABAA receptor subunit a1 in rat auditory cortex, inferior colliculus and dorsal cochlear nucleus following noise-induced hearing loss', Society for Neuroscience. Meeting, Chicago, Ill..

Other Publications

2022, 'Electroporation System for Controlled Localized Therapeutics Delivery', Patent

Cherylea’s research interests include;

Mal de Debarquement Syndrome (MdDS)

Specifically, understanding the basic clinical features, the underlying hormonal aspects and autonomic nervous system maladaptation in MdDS patients. For more information go to the Mal de Debarquement Research Group page.

What is Mal de Debarquement Syndrome?- YouTube Video created by Dr Cherylea Browne.

Email Dr Browne for research student opportunities.

Want to support our next research project? Click here to find out more: https://crowd.science/campaigns/research-into-the-pathophysiology-and-therapy-options-of-mal-de-debarquement-syndrome/

Molecular Gene Therapy

Specifically, the development of enhanced of neural interfaces by utilising 'close-field' electroporation to enable electro-gene transfer of therapeutic genes.For more information, go to the Translational Neuroscience Facility - Sensori-motor Group page

Vestibular and Occulomotor Deficits in Post-Concussion Syndrome

https://www.researchgate.net/profile/Cherylea_Browne