Doctor Ahmed Moustafa

Biography

I graduated from Cairo University, with a bachelor’s degree in mathematics and computer science. I have spent almost 10 years in the US (University of Louisiana, University of Arizona, and Rutgers University) conducting computational and neuropsychological studies of schizophrenia and Parkinson’s disease (during my PhD and postdoctoral work). Starting from 2010, I have also started collaborative projects on depression and posttraumatic stress disorder (PTSD). In 2012, I joined UWS, and I am glad to teach and conduct research in the field of cognitive and clinical neuropsychology.

My research interests lie at the intersection of Computational Modeling, Cognitive Neuroscience, and Clinical Neuropsychology. Currently, I am interested in understanding learning and cognitive function in various psychiatric and neurological disorders, including (but not limited to) the following:

  • Schizophrenia
  • Parkinson’s disease
  • Depression
  • Posttraumatic stress disorder (PTSD)
  • ADHD

I plan to study cognitive function in these patients using both computational modeling and behavioral methods. One of research goals is to understand how changes in cognitive function (such as working memory, learning, memory, attention, and language) relate to psychometric measures (such as personality, intelligence, and quality of life) in patients with brain disorders.

I welcome new students who have interests in conducting computational and/or cognitive/behavioral studies, and with any of the above patient groups (or other). If interested, please email me if you have any questions or if you want to arrange a meeting.

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Areas of Research / Teaching Expertise

Cognitive Neuroscience, Computational Modeling of Brain and Behavioral Processes, Neural Networks, Cognitive and Clinical Neuropsychology.

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Grants / Current Projects

How Dopaminergic Medication Impacts Feedback Learning and Decision Making in Parkinson’s Patients.

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Selected Publications

Journal Articles:

Krishna, R.*, Moustafa, A.A*., Eby, A. Skeen , L.C., Myers, C. E. (2012). Learning and generalization in healthy aging: implication for striato-frontal and hippocampal function (opens in a new window) Cognitive and Behavioral Neurology. (* authors contributed equally to this work)

Moustafa, A. A. & Gluck, M. A. (2011). Computational cognitive models of prefrontal-striatal- hippocampal interactions in Parkinson's disease and schizophrenia. (opens in a new window) Neural Networks 24(6):575-591.

Somali. Z., Moustafa, A. A., Keri, S., M., Myers, C.E., Gluck, M. A. (2011). General functioning predicts reward and punishment learning in schizophrenia. Schizophrenia Research, (opens in a new window) 127(1-3):131-6.

Moustafa, A. A., & Gluck, M. A. (2011). A neurocomputational model of dopamine and prefrontal-striatal interactions during multi-cue category learning by Parkinson's patients. Journal of Cognitive Neuroscience, (opens in a new window) 23(1):151-167.

Moustafa, A. A. (2011). A computational model of cognitive deficits in medicated and unmedicated Parkinson’s disease patients. Functional Neurology, Rehabilitation, and Ergonomics (opens in a new window) 1(2):251-270

Moustafa, A. A., Keri, S., Herzallah, M., Myers, C.E., Gluck, M. A. (2010). A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and Cognition, (opens in a new window) 74(2):132-44.

Keri, S, Moustafa, A. A., Myers, C. E., Benedek, G. & Gluck, M. A. (2010). Alpha-synuclein locus duplication impairs reward-learning. Proceedings of the National Academy of Sciences (PNAS), (opens in a new window) 107(36):15992-4.

Herzallah, M., Moustafa, A.A., Misk, A., Myers, C. E., & Gluck, M.A. (2010). Depression impairs acquisition, while anticholinergics impair transfer generalization in Parkinson’s patients. Cognitive and Behavioral Neurology, 23(2), 98-105.

Moustafa, A. A., Myers, C. E., Gluck, M. A. (2009). A neurocomputational model of classical conditioning phenomena: A putative role for the hippocampal region in associative learning. Brain Research, 1276, 180-95.

Bódi, N., Kéri, S. Nagy, H., Moustafa, A. A., Myers, C. E., Dibó, G., Takáts,A., Bereczky, D., Gluck., M. A. (2009). Reward learning and the novelty seeking personality: A between and within-subjects study of the effects of dopamine agonists on young Parkinson's patients. Brain, 132, 2385-2395.

Moustafa, A. A., Cohen, M. X., Sherman, S. J., Frank, M. J . (2008). A role for dopamine in temporal decision making and reward maximization in Parkinsonism. Journal of Neuroscience, 28(47), 12294-12304

Moustafa, A.A., Sherman, S.J. & Frank, M.J. (2008). A dopaminergic basis for working memory, learning and attentional shifting in Parkinsonism. Neuropsychologia, 46, 3144-3156

Moustafa, A. A., & Maida, A. S. (2007). Using TD learning to simulate working memory performance in a model of the prefrontal cortex and basal ganglia. Cognitive Systems Research, 8, 262-281.

Frank, M. J., Moustafa, A. A., Haughey, H. M., Curran, T., & Hutchison, K. E. (2007). Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning. Proc Natl Acad Sci U S A, 104(41), 16311-16316.

Frank, M.J., Samanta, J., Moustafa, A.A. & Sherman, S.J. (2007). Hold your horses: Impulsivity, deep brain stimulation and medication in Parkinsonism. Science, 318, 1309-1312.

Invited Commentary:

Moustafa, A. A. (2011). Levodopa enhances reward learning but impairs reversal learning in Parkinson’s disease patients. Frontiers in Human Neuroscience, 4:240.

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Memberships and Engagement


Society for Neuroscience (SFN)
Cognitive Neuroscience Society (CNS)
Neuroscience Group of Egypt (NGE)
Society for Computational Modeling of Associative Learning
International Brain Research Organization (IBRO)
International Behavioral Neuroscience Society (IBNS)

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