Herbal medicine for the management of osteoarthritis of the knee

Currently there is no cure or intervention to stop the progression of osteoarthritis. Although pharmaceutical interventions offer effective pain management, they can only be used in the short term due to the potential for serious complications from long term use.

Researchers at NICM Health Research Institute are seeking participants to join a clinical trial investigating the effectiveness and safety of a herbal medicine for the management of osteoarthritis of the knee. Our study will examine if this herbal formulation can reduce knee pain due to osteoarthritis, improve functionality and physical movement, as well as overall wellbeing.

Recruitment is now underway for volunteers to participate in the study.

Who can join?

  • Men and women aged between 40 and 75.
  • Men and women who:
    • have primary osteoarthritis in at least one knee.
    • have mild to moderate knee pain.
    • have a body mass index (BMI) of 35 or less.

What’s involved?

  • Initial phone screening.
  • All meetings conducted remotely through Video calls with online questionnaire's and physical function assessments.
  • Herbal medicine to be taken twice daily (morning and night) during the 12-week study.
  • Complete a daily diary for the duration of the 12-week study.
  • Have two blood tests, one at the beginning and one at the end of the study.

During this study, the use of analgesics or non-steroidal anti-inflammatory drugs will not be allowed, or any other supplement for osteoarthritis such as chondroitin, fish oils, omega 3 and 6, joint repair formulations or avocado soybean unsapponables. However, Paracetamol is allowed if required.

What are the benefits of participating?

  • You may experience less pain, improved function and overall wellbeing.
  • You will be reimbursed up to $30 per visit (maximum three visits) for your travel expenses to the study centre.
  • You will be helping to advance medical research by contributing to a potential new clinically validated formulation for the management of osteoarthritis.

For more details about the study please read the information sheet below before deciding on whether to participate or not in this study.

For more information, please contact:

Christine Murray
Study Principal Investigator

e.      christine.murray@westernsydney.edu.au
p.      0488 228 474

Interested in participating?

Please complete and submit the following information.


This study is supported by Australian Government Research Training Program Scholarship and NICM-Blackmores Institute Scholarship Program. This clinical trial is approved by Western Sydney University Human Research Ethics Committee (Approval Number: H13062).

Chief Investigator: Professor Alan Bensoussan, NICM Health Research Institute