School of Science research seminar

Event Name
School of Science research seminar
12 June 2020
12:30 pm - 01:30 pm

Address (Room): Zoom Meeting ID: 484 163 7742


Zoom Meeting ID: 484 163 7742 Emily Bryan, Kate Redgrove, Bettina Mihalas, Jessie Sutherland, Alison Carey, Charles Armitage, Logan K Trim, Avinash Kollipara, Robert McLachlan, Kenneth W Beagley, Eileen McLaughlin School of Biomedical Sciences and Institute of Health & Biomedical Innovation, Queensland University of Technology, School of Environmental and Life Sciences, Faculty of Science, The University of Newcastle, School of Science, Western Sydney University, Australia. Hiding in plain sight - chlamydial infection in the male Abstract: The incidence of Chlamydia infection, in both females and males, is increasing world-wide. Male infections have been associated clinically with urethritis, epididymitis and orchitis, believed to be caused by ascending infection, although the impact of infection on male fertility remains controversial. Using a mouse model of male chlamydial infection, we have demonstrated long lasting chronic infection in the testes resulting in germ cell DNA damage, impaired spermatogenesis, autoimmune disease, intergenerational effects on offspring and a haematogenous route of infection. Concomitant studies in human male infertility patients has revealed a hitherto unexpectedly high incidence of active chlamydial infection in asymptomatic men undergoing testicular biopsy for fertility assessment and assisted reproduction treatments, associated with a wide range of spermatogenic defects.

Web page:

Name: Patrice Castignolles

Phone: 0413 021 562

School / Department: Science