Donovin Coles

Candidature

PhD Candidate

Thesis title

Controlling Contagion: Identifying and targeting genetic loci in agricultural crops to improve broad-spectrum disease resistance

Research project

Chickpea (Cicer arietinum) is an important staple food source in many countries and a vital source of protein in developing countries whereas canola (Brassica napus) is important both as an edible oil and for biofuel production. Due to an increase in demand, the production of chickpea and canola have almost doubled in the last 20 years. However, a threat to sustaining production are plant pathogens which cause major losses worldwide. Reducing losses due to the diseases caused by pathogens requires a fundamental understanding of how they infect their hosts. Hemibiotrophic pathogens are a group of pathogens that initially colonise plant tissue without causing symptoms and then later switch to a destructive phase associated with mass tissue necrosis. To date, the control mechanisms regulating the balance between the two lifestyles is not well understood. For my PhD research project, I am investigating the mechanisms regulating pathogenesis in two model hemibiotrophs: the oomycete Phytophthora medicaginis (host: chickpea) and the fungal pathogen Leptosphaeria maculans (host: canola). The identification of factors controlling the balance between the biotrophic and necrotrophic life stages may provide novel targets to prevent yield reducing disease caused by these pathogens.

Publication

Naidoo S, Slippers B, Plett JM, Coles D, Oates CN, (2019) 'The Road to Resistance in Forest Trees', Frontiers in Plant Science, vol.10, Article no.273

Supervisors

Dr Jonathan Plett, Dr Henrik Stotz (University of Hertsfordshire), Dr William Cuddy (DPI)